Ablation of Promyelocytic Leukemia Protein (PML) Re-patterns Energy Balance and Protects Mice from Obesity Induced by a Western Diet

Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells

(2012) Xiwen Cheng et al.   BMC GENOMICS

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

(2012) C. Flannery et al.   DIABETES

LKB1 and AMPK: central regulators of lymphocyte metabolism and function

(2012) Julianna Blagih et al.   IMMUNOLOGICAL REVIEWS

Targeting Promyelocytic Leukemia Protein: A Means to Regulating PML Nuclear Bodies

(2012) Erin L. Reineke et al.   International Journal of Biological Sciences

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

(2012) Ellen Van Damme et al.   International Journal of Biological Sciences

Promyelocytic Leukemia Protein (PML) Regulates Endothelial Cell Network Formation and Migration in Response to Tumor Necrosis Factor α (TNFα) and Interferon α (IFNα)

(2012) Xiwen Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A metabolic prosurvival role for PML in breast cancer

(2012) Arkaitz Carracedo et al.   JOURNAL OF CLINICAL INVESTIGATION

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice

(2011) Myung K. Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitogen-activated Protein Kinase Extracellular Signal-regulated Kinase 2 Phosphorylates and Promotes Pin1 Protein-dependent Promyelocytic Leukemia Protein Turnover

(2011) Jun Hee Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

(2011) Claudio Mauro et al.   NATURE CELL BIOLOGY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

The Randle cycle revisited: a new head for an old hat

(2009) Louis Hue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice

(2009) Shian-Huey Chiang et al.   CELL

Histone Deacetylase 7 Promotes PML Sumoylation and Is Essential for PML Nuclear Body Formation

(2008) C. Gao et al.   MOLECULAR AND CELLULAR BIOLOGY

Signal-dependent Regulation of Transcription by Histone Deacetylase 7 Involves Recruitment to Promyelocytic Leukemia Protein Nuclear Bodies

(2008) Chengzhuo Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Resistance to diet-induced obesity in mice with a single substituted chromosome

(2008) David A. Buchner et al.   PHYSIOLOGICAL GENOMICS