Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

(2012) Sandro Keller et al.   ANALYTICAL CHEMISTRY

The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation

(2012) Rebekah R. Bartelt et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

On the Distribution of Protein Refractive Index Increments

(2011) Huaying Zhao et al.   BIOPHYSICAL JOURNAL

Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation

(2011) Rémi Lasserre et al.   JOURNAL OF CELL BIOLOGY

The SLP-76 Src Homology 2 Domain Is Required for T Cell Development and Activation

(2011) J. C. Burns et al.   JOURNAL OF IMMUNOLOGY

Functional Cooperation between the Proteins Nck and ADAP Is Fundamental for Actin Reorganization

(2011) M. H. Pauker et al.   MOLECULAR AND CELLULAR BIOLOGY

Vav1-Mediated Scaffolding Interactions Stabilize SLP-76 Microclusters and Contribute to Antigen-Dependent T Cell Responses

(2011) N. R. Sylvain et al.   Science Signaling

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

(2010) Mira Barda-Saad et al.   EMBO JOURNAL

Identification of Phosphorylation-Dependent Interaction Partners of the Adapter Protein ADAP using Quantitative Mass Spectrometry: SILAC vs18O-Labeling

(2010) Sabine Lange et al.   JOURNAL OF PROTEOME RESEARCH

Using Lamm-Equation modeling of sedimentation velocity data to determine the kinetic and thermodynamic properties of macromolecular interactions

(2010) Chad A. Brautigam   METHODS

T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering

(2010) A. Hashimoto-Tane et al.   MOLECULAR AND CELLULAR BIOLOGY

Adhesion and Degranulation Promoting Adapter Protein (ADAP) Is a Central Hub for Phosphotyrosine-Mediated Interactions in T Cells

(2010) Marc Sylvester et al.   PLoS One

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

(2010) L. Balagopalan et al.   Cold Spring Harbor Perspectives in Biology

Aggregation of Membrane Proteins by Cytosolic Cross-Linkers: Theory and Simulation of the LAT-Grb2-SOS1 System

(2009) Ambarish Nag et al.   BIOPHYSICAL JOURNAL

The Adapter Protein SLP-76 Mediates "Outside-In" Integrin Signaling and Function in T Cells

(2009) R. G. Baker et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphotyrosine-dependentin vitroreconstitution of recombinant LAT-nucleated multiprotein signalling complexes on liposomes

(2009) Dhaval Sangani et al.   MOLECULAR MEMBRANE BIOLOGY

SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility

(2009) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Cell Costimulation via the Integrin VLA-4 Inhibits the Actin-Dependent Centralization of Signaling Microclusters Containing the Adaptor SLP-76

(2008) Ken Nguyen et al.   IMMUNITY

SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion

(2008) Hongyan Wang et al.   TRENDS IN CELL BIOLOGY