A Phosphatidylinositol 3-Kinase-Pax3 Axis Regulates Brn-2 Expression in Melanoma

Novel Somatic Mutations to PI3K Pathway Genes in Metastatic Melanoma

(2012) Austin Y. Shull et al.   PLoS One

Differential PAX3 functions in normal skin melanocytes and melanoma cells

(2011) Sandra Medic et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oncogenic BRAF Induces Melanoma Cell Invasion by Downregulating the cGMP-Specific Phosphodiesterase PDE5A

(2011) Imanol Arozarena et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway

(2011) A E Thurber et al.   ONCOGENE

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny

(2011) Y Cheli et al.   ONCOGENE

The role of mitogen- and stress-activated protein kinase pathways in melanoma

(2011) Pablo Lopez-Bergami   Pigment Cell & Melanoma Research

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor

(2011) Glen M. Boyle et al.   Pigment Cell & Melanoma Research

Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis

(2010) C Nogueira et al.   ONCOGENE

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene

(2010) Dominique Kobi et al.   Pigment Cell & Melanoma Research

The discovery of the microphthalmia locus and its gene, Mitf

(2010) Heinz Arnheiter   Pigment Cell & Melanoma Research

PI3Kγ activation by CXCL12 regulates tumor cell adhesion and invasion

(2009) María Monterrubio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

(2009) S. Pinner et al.   CANCER RESEARCH

Phosphatidylinositol-3-Kinase as a Therapeutic Target in Melanoma

(2009) S. A. Aziz et al.   CLINICAL CANCER RESEARCH

Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model

(2009) C. Michailidou et al.   Disease Models & Mechanisms

Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription

(2009) Tania Christova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Fifteen-year quest for microphthalmia-associated transcription factor target genes

(2009) Yann Cheli et al.   Pigment Cell & Melanoma Research

The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma

(2009) SubbaRao V. Madhunapantula et al.   Pigment Cell & Melanoma Research

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

(2008) J. Goodall et al.   CANCER RESEARCH

PAX3 expression in primary melanomas and nevi

(2008) Rebecca S Plummer et al.   MODERN PATHOLOGY

POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis

(2008) Anthony L. Cook et al.   Pigment Cell & Melanoma Research

Pigmentation PAX-ways: the role of Pax3 in melanogenesis, melanocyte stem cell maintenance, and disease

(2008) Jennifer D. Kubic et al.   Pigment Cell & Melanoma Research

Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF

(2008) Claudia Wellbrock et al.   PLoS One