Transcription Factors KLF1 and KLF2 Positively Regulate Embryonic and Fetal β-Globin Genes through Direct Promoter Binding

Compound heterozygosity for KLF1 mutations associated with remarkable increase of fetal hemoglobin and red cell protoporphyrin

(2011) S. Satta et al.   HAEMATOLOGICA

A Dominant Mutation in the Gene Encoding the Erythroid Transcription Factor KLF1 Causes a Congenital Dyserythropoietic Anemia

(2010) Lionel Arnaud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf

(2010) J. Isern et al.   BLOOD

Crosstalk between histone modifications maintains the developmental pattern of gene expression on a tissue-specific locus

(2010) Alison M. Hosey et al.   Epigenetics

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

Mammalian Krüppel-Like Factors in Health and Diseases

(2010) Beth B. McConnell et al.   PHYSIOLOGICAL REVIEWS

Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor

(2010) M. Siatecka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A spectrum of gene regulatory phenomena at mammalian β-globin gene lociThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2009) George Fromm et al.   Biochemistry and Cell Biology

Histone hyperacetylation within the  -globin locus is context-dependent and precedes high-level gene expression

(2009) G. Fromm et al.   BLOOD

KLF2 Transcription-Factor Deficiency in T Cells Results in Unrestrained Cytokine Production and Upregulation of Bystander Chemokine Receptors

(2009) Michael A. Weinreich et al.   IMMUNITY

The Higher Structure of Chromatin in the LCR of the β-Globin Locus Changes during Development

(2009) Xiangdong Fang et al.   JOURNAL OF MOLECULAR BIOLOGY

BRG1 directly regulates nucleosome structure and chromatin looping of the α globin locus to activate transcription

(2009) Shin-Il Kim et al.   NUCLEIC ACIDS RESEARCH

Joining the loops: β-Globin gene regulation

(2008) Daan Noordermeer et al.   IUBMB LIFE

A Network of Krüppel-like Factors (Klfs)

(2008) Sally A. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetylation of EKLF Is Essential for Epigenetic Modification and Transcriptional Activation of the  -Globin Locus

(2008) T. Sengupta et al.   MOLECULAR AND CELLULAR BIOLOGY

Failure of Terminal Erythroid Differentiation in EKLF-Deficient Mice Is Associated with Cell Cycle Perturbation and Reduced Expression of E2F2

(2008) A. M. Pilon et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetics of β-globin gene regulation

(2008) Christine M. Kiefer et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A core Klf circuitry regulates self-renewal of embryonic stem cells

(2008) Jianming Jiang et al.   NATURE CELL BIOLOGY

CTCF-dependent enhancer-blocking by alternative chromatin loop formation

(2008) C. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA