PINCH Proteins Regulate Cardiac Contractility by Modulating Integrin-Linked Kinase-Protein Kinase B Signaling

Targeted Next-Generation Sequencing for the Molecular Genetic Diagnostics of Cardiomyopathies

(2011) Benjamin Meder et al.   Circulation-Cardiovascular Genetics

Integrin-linked kinase: a Scaffold protein unique among its ilk

(2011) Lina Dagnino   Journal of Cell Communication and Signaling

JunB-CBF  signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure

(2010) B. Meder et al.   JOURNAL OF CELL SCIENCE

PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1α

(2010) Iris Eke et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrin-Linked Kinase Is a Functional Mn2+-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation

(2010) Mykola Maydan et al.   PLoS One

Targeted Ablation of PINCH1 and PINCH2 From Murine Myocardium Results in Dilated Cardiomyopathy and Early Postnatal Lethality

(2009) Xingqun Liang et al.   CIRCULATION

A Single Serine in the Carboxyl Terminus of Cardiac Essential Myosin Light Chain-1 Controls Cardiomyocyte Contractility In Vivo

(2009) Benjamin Meder et al.   CIRCULATION RESEARCH

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

(2009) Sara A Wickström et al.   EMBO JOURNAL

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

(2009) David Hassel et al.   NATURE MEDICINE