E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation

Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis

(2012) Liren Liu et al.   CELL RESEARCH

Lack of Cul4b, an E3 Ubiquitin Ligase Component, Leads to Embryonic Lethality and Abnormal Placental Development

(2012) Baichun Jiang et al.   PLoS One

Cul4A is essential for spermatogenesis and male fertility

(2011) Dragana Kopanja et al.   DEVELOPMENTAL BIOLOGY

Cullin 4B Protein Ubiquitin Ligase Targets Peroxiredoxin III for Degradation

(2011) Xi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-Linked Mental Retardation Gene CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Component WDR5 and Regulates Neuronal Gene Expression

(2011) Tadashi Nakagawa et al.   MOLECULAR CELL

The cullin protein family

(2011) Antonio Sarikas et al.   GENOME BIOLOGY

Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks

(2010) Claudia Kerzendorfer et al.   HUMAN MOLECULAR GENETICS

DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress

(2009) V. Leung-Pineda et al.   CANCER RESEARCH

The multiple levels of regulation by p53 ubiquitination

(2009) J T Lee et al.   CELL DEATH AND DIFFERENTIATION

Characterization of Nuclear Localization Signal in the N Terminus of CUL4B and Its Essential Role in Cyclin E Degradation and Cell Cycle Progression

(2009) Yongxin Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis

(2009) Liren Liu et al.   MOLECULAR CELL

CRL4s: the CUL4-RING E3 ubiquitin ligases

(2009) Sarah Jackson et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

(2008) T. Abbas et al.   GENES & DEVELOPMENT

The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

(2008) Y. Kim et al.   GENES & DEVELOPMENT

Cullin-RING ubiquitin ligases: global regulation and activation cycles

(2008) Dimple R Bosu et al.   Cell Division