Characterization of Nuclear Localization Signal in the N Terminus of CUL4B and Its Essential Role in Cyclin E Degradation and Cell Cycle Progression

DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress

(2009) V. Leung-Pineda et al.   CANCER RESEARCH

CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis

(2009) Liren Liu et al.   MOLECULAR CELL

Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage

(2009) Zhaojian Liu et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Proliferation defects and genome instability in cells lacking Cul4A

(2009) D Kopanja et al.   ONCOGENE

Sp1 and CREB regulate basal transcription of the human SNF2L gene

(2008) Yu Xia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis

(2008) D. L. Waning et al.   BLOOD

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

(2008) G. A. Miranda-Carboni et al.   GENES & DEVELOPMENT

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

(2008) T. Abbas et al.   GENES & DEVELOPMENT

The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

(2008) Y. Kim et al.   GENES & DEVELOPMENT

CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1Cdt2Pathway during S Phase and after UV Irradiation

(2008) Hideo Nishitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cullin-RING ubiquitin ligases: global regulation and activation cycles

(2008) Dimple R Bosu et al.   Cell Division