Phosphotyrosine Signaling Proteins that Drive Oncogenesis Tend to be Highly Interconnected

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling

(2011) Andre Scott Jung et al.   CELL CYCLE

A Conserved Residue in the Yeast Bem1p SH3 Domain Maintains the High Level of Binding Specificity Required for Function

(2011) Maryna Gorelik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid Phospho-Turnover by Receptor Tyrosine Kinases Impacts Downstream Signaling and Drug Binding

(2011) Laura B. Kleiman et al.   MOLECULAR CELL

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Controllability of complex networks

(2011) Yang-Yu Liu et al.   NATURE

Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy

(2011) I. Letunic et al.   NUCLEIC ACIDS RESEARCH

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

(2011) Lydia W.T. Cheung et al.   Cancer Discovery

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Tarp regulates earlyChlamydia-induced host cell survival through interactions with the human adaptor protein SHC1

(2010) Adrian Mehlitz et al.   JOURNAL OF CELL BIOLOGY

SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity

(2010) Bernard A. Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantifying protein–protein interactions in high throughput using protein domain microarrays

(2010) Alexis Kaushansky et al.   Nature Protocols

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

Tyrosine-Phosphorylated Caveolin-1 Blocks Bacterial Uptake by Inducing Vav2-RhoA-Mediated Cytoskeletal Rearrangements

(2010) Jan Peter Boettcher et al.   PLOS BIOLOGY

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

(2009) William E Tidyman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

(2009) William W Chen et al.   Molecular Systems Biology

System-wide Investigation of ErbB4 Reveals 19 Sites of Tyr Phosphorylation that Are Unusually Selective in Their Recruitment Properties

(2008) Alexis Kaushansky et al.   CHEMISTRY & BIOLOGY

A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R

(2008) Alexis Kaushansky et al.   Molecular BioSystems

Protein-protein interaction networks and biology—what's the connection?

(2008) Luke Hakes et al.   NATURE BIOTECHNOLOGY

An empirical framework for binary interactome mapping

(2008) Kavitha Venkatesan et al.   NATURE METHODS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Drug development of MET inhibitors: targeting oncogene addiction and expedience

(2008) Paolo M. Comoglio et al.   NATURE REVIEWS DRUG DISCOVERY

Linear Motif Atlas for Phosphorylation-Dependent Signaling

(2008) M. L. Miller et al.   Science Signaling