Glycoprotein Disease Markers and Single Protein-omics

Quantitative Structural Characterization of Local N-Glycan Microheterogeneity in Therapeutic Antibodies by Energy-Resolved Oxonium Ion Monitoring

(2012) Atsuhiko Toyama et al.   ANALYTICAL CHEMISTRY

Top-Down Approach for the Direct Characterization of Low Molecular Weight Heparins Using LC-FT-MS

(2012) Lingyun Li et al.   ANALYTICAL CHEMISTRY

Integrated approach toward the discovery of glyco-biomarkers of inflammation-related diseases

(2012) Takashi Angata et al.   Annals of the New York Academy of Sciences

Glycan array analysis of the antigen repertoire targeted by tumor-binding antibodies

(2012) Jeffrey C. Gildersleeve et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Increased Levels of Tetra-antennary N-Linked Glycan but Not Core Fucosylation Are Associated with Hepatocellular Carcinoma Tissue

(2012) A. Mehta et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Glycosylation of prostate specific antigen and its potential diagnostic applications

(2012) Tijl Vermassen et al.   CLINICA CHIMICA ACTA

Using lectins to harvest the plasma/serum glycoproteome

(2012) Susan Fanayan et al.   ELECTROPHORESIS

Identifying cancer biomarkers by mass spectrometry-based glycomics

(2012) Yehia Mechref et al.   ELECTROPHORESIS

The bisecting GlcNAc in cell growth control and tumor progression

(2012) Hazuki E. Miwa et al.   GLYCOCONJUGATE JOURNAL

Ovarian Cancer Screening

(2012) Steven J. Skates   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB

(2012) Hiroyuki Kaji et al.   JOURNAL OF PROTEOME RESEARCH

Semi-Automated Identification of N-Glycopeptides by Hydrophilic Interaction Chromatography, nano-Reverse-Phase LC–MS/MS, and Glycan Database Search

(2012) Petr Pompach et al.   JOURNAL OF PROTEOME RESEARCH

A lectin-coupled, targeted proteomic mass spectrometry (MRM MS) platform for identification of multiple liver cancer biomarkers in human plasma

(2012) Yeong Hee Ahn et al.   Journal of Proteomics

Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers

(2012) Jean-Luc Chaubard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycomic and Proteomic Profiling of Pancreatic Cyst Fluids Identifies Hyperfucosylated Lactosamines on theN-linked Glycans of Overexpressed Glycoproteins

(2012) Benjamin F. Mann et al.   MOLECULAR & CELLULAR PROTEOMICS

Determination of site-specific glycan heterogeneity on glycoproteins

(2012) Daniel Kolarich et al.   Nature Protocols

Site-specific chemical protein conjugation using genetically encoded aldehyde tags

(2012) David Rabuka et al.   Nature Protocols

Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation

(2012) Katie Partyka et al.   PROTEOMICS

Quantification of glycopeptides by multiple reaction monitoring liquid chromatography/tandem mass spectrometry

(2012) Ehwang Song et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Ultrasensitive Characterization of Site-Specific Glycosylation of Affinity-Purified Haptoglobin from Lung Cancer Patient Plasma Using 10 μm i.d. Porous Layer Open Tubular Liquid Chromatography−Linear Ion Trap Collision-Induced Dissociation/Electron Transfer Dissociation Mass Spectrometry

(2011) Dongdong Wang et al.   ANALYTICAL CHEMISTRY

The Tn Antigen-Structural Simplicity and Biological Complexity

(2011) Tongzhong Ju et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Screening for ovarian cancer in the general population

(2011) Aleksandra Gentry-Maharaj et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Development of recombinant Aleuria aurantia lectins with altered binding specificities to fucosylated glycans

(2011) Patrick R. Romano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The human epithelial carcinoma antigen recognized by monoclonal antibody AE3 is expressed on a sulfoglycolipid in addition to neoplastic mucins

(2011) Angelina S. Palma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer

(2011) V. Padler-Karavani et al.   CANCER RESEARCH

Clinical utility of highly sensitive Lens culinaris agglutinin-reactive alpha-fetoprotein in hepatocellular carcinoma patients with alpha-fetoprotein

(2011) Hidenori Toyoda et al.   CANCER SCIENCE

hCG, five independent molecules

(2011) Laurence A. Cole   CLINICA CHIMICA ACTA

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family

(2011) E. P. Bennett et al.   GLYCOBIOLOGY

Identification of new cancer biomarkers based on aberrant mucin glycoforms byin situproximity ligation

(2011) Rita Pinto et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

(2011) Catharina Steentoft et al.   NATURE METHODS

Galectin-1-Binding Glycoforms of Haptoglobin with Altered Intracellular Trafficking, and Increase in Metastatic Breast Cancer Patients

(2011) Michael C. Carlsson et al.   PLoS One

Identification of blood-protein carriers of the CA 19-9 antigen and characterization of prevalence in pancreatic diseases

(2011) Tingting Yue et al.   PROTEOMICS

Glycan labeling strategies and their use in identification and quantification

(2010) L. R. Ruhaak et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Cancer Biomarkers Defined by Autoantibody Signatures to Aberrant O-Glycopeptide Epitopes

(2010) H. H. Wandall et al.   CANCER RESEARCH

Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints

(2010) Dorota F. Zielinska et al.   CELL

Serum tumor markers and their utilization in the management of germ-cell tumors in adult males

(2010) Mohamed Salem et al.   Expert Review of Anticancer Therapy

Mass Spectrometry Based Glycoproteomics—From a Proteomics Perspective

(2010) Sheng Pan et al.   MOLECULAR & CELLULAR PROTEOMICS

The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF

(2010) M E Behrens et al.   ONCOGENE

Specific posttranslational modification regulates early events in mammary carcinoma formation

(2010) H.-B. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Location, location, location: new insights into O-GalNAc protein glycosylation

(2010) David J. Gill et al.   TRENDS IN CELL BIOLOGY

Metabolism, Cell Surface Organization, and Disease

(2009) James W. Dennis et al.   CELL

Differences in Recognition of the 1st WHO International Reference Reagents for hCG-Related Isoforms by Diagnostic Immunoassays for Human Chorionic Gonadotropin

(2009) C. M. Sturgeon et al.   CLINICAL CHEMISTRY

Microarrays in Glycoproteomics Research

(2009) Tingting Yue et al.   CLINICS IN LABORATORY MEDICINE

Mass spectrometry in the analysis of N-linked and O-linked glycans

(2009) Simon J North et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma

(2009) Jorge A. Marrero et al.   GASTROENTEROLOGY

A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data

(2009) Frederick J Krambeck et al.   GLYCOBIOLOGY

Quantitative Analysis of an Aberrant Glycoform of TIMP1 from Colon Cancer Serum by L-PHA-Enrichment and SISCAPA with MRM Mass Spectrometry

(2009) Yeong Hee Ahn et al.   JOURNAL OF PROTEOME RESEARCH

Tandem18O Stable Isotope Labeling for Quantification of N-Glycoproteome

(2009) Ze Liu et al.   JOURNAL OF PROTEOME RESEARCH

A Perspective on Challenges and Issues in Biomarker Development and Drug and Biomarker Codevelopment

(2009) S. E. Taube et al.   JNCI-Journal of the National Cancer Institute

GlycoFibroTest Is a Highly Performant Liver Fibrosis Biomarker Derived from DNA Sequencer-based Serum Protein Glycomics

(2009) Dieter Vanderschaeghe et al.   MOLECULAR & CELLULAR PROTEOMICS

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

(2009) Thomas J. Boltje et al.   Nature Chemistry

Identification of candidate biomarkers with cancer-specific glycosylation in the tissue and serum of endometrioid ovarian cancer patients by glycoproteomic analysis

(2009) Karen L. Abbott et al.   PROTEOMICS

Altered Glycosylation of Proteins in Cancer: What Is the Potential for New Anti-Tumour Strategies

(2008) S. Brooks et al.   Anti-Cancer Agents in Medicinal Chemistry

Lectin‐based electrophoretic analysis of the expression of the 35 kDa inter‐α‐trypsin inhibitor heavy chain H4 fragment in sera of patients with five different malignancies

(2008) Emida Mohamed et al.   ELECTROPHORESIS

N-Glycans in cancer progression

(2008) K. S Lau et al.   GLYCOBIOLOGY

On-line separations combined with MS for analysis of glycosaminoglycans

(2008) Joseph Zaia   MASS SPECTROMETRY REVIEWS

Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation

(2008) James N. Arnold et al.   PROTEOMICS

Liquid chromatography/tandem mass spectrometric method for the quantification of eight proteolytic fragments of ITIH4with biomarker potential in human plasma and serum

(2008) Irene van den Broek et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Sweet and sour: the impact of sugars on disease

(2008) A. Alavi et al.   RHEUMATOLOGY