Integrated approach toward the discovery of glyco-biomarkers of inflammation-related diseases

Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

(2014) S. Schoonbroodt et al.   JOURNAL OF IMMUNOLOGY

Development of an antibody-lectin enzyme immunoassay for fucosylated α-fetoprotein

(2012) Hiroaki Korekane et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands

(2011) Prakash Radhakrishnan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Systems glycobiology: biochemical reaction networks regulating glycan structure and function

(2011) S. Neelamegham et al.   GLYCOBIOLOGY

Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array

(2011) Francis Jacob et al.   INTERNATIONAL JOURNAL OF CANCER

Brain-specific Expression ofN-Acetylglucosaminyltransferase IX (GnT-IX) Is Regulated by Epigenetic Histone Modifications

(2011) Yasuhiko Kizuka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

History and recent progress in evaluation of the fucosylated alpha-fetoprotein fraction

(2011) Yutaka Aoyagi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Association of fucosyltransferase 8 (FUT8) polymorphism Thr267Lys with pulmonary emphysema

(2011) Miki Yamada et al.   JOURNAL OF HUMAN GENETICS

Biomarkers: Warning signs

(2011) Ruth Williams   NATURE

Perspective: In search of biomarkers

(2011) Neil S. Buckholtz   NATURE

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid  -peptides in human cerebrospinal fluid

(2011) A. Halim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

A sensitive assay to measure biomarker glycosylation demonstrates increased fucosylation of prostate specific antigen (PSA) in patients with prostate cancer compared with benign prostatic hyperplasia

(2010) Miriam V. Dwek et al.   CLINICA CHIMICA ACTA

Multilectin Assay for Detecting Fibrosis-Specific Glyco-Alteration by Means of Lectin Microarray

(2010) A. Kuno et al.   CLINICAL CHEMISTRY

Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC

(2010) Kazuki Nakajima et al.   GLYCOBIOLOGY

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identifying and validating biomarkers for Alzheimer's disease

(2010) Christian Humpel   TRENDS IN BIOTECHNOLOGY

Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease

(2010) Jayaji M Moré et al.   BMC Pulmonary Medicine

Genomics Meets Glycomics—The First GWAS Study of Human N-Glycome Identifies HNF1α as a Master Regulator of Plasma Protein Fucosylation

(2010) Gordan Lauc et al.   PLoS Genetics

The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows

(2010) Toshiaki Katayama et al.   Journal of Biomedical Semantics

Engineering a versatile tandem repeat-type α2-6sialic acid-binding lectin

(2009) Rikio Yabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Common Coding Variants of the HNF1A Gene Are Associated With Multiple Cardiovascular Risk Phenotypes in Community-Based Samples of Younger and Older European-American Adults

(2009) Alexander P. Reiner et al.   Circulation-Cardiovascular Genetics

Detection of Hepatocellular Carcinoma Using Glycomic Analysis

(2009) R. Goldman et al.   CLINICAL CANCER RESEARCH

A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics

(2009) Hisashi Narimatsu et al.   FEBS Journal

Protective effect of N-glycan bisecting GlcNAc residues on  -amyloid production in Alzheimer's disease

(2009) K. Akasaka-Manya et al.   GLYCOBIOLOGY

 1,2-Fucosylated and  -N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer

(2009) K. Fukushima et al.   GLYCOBIOLOGY

Strategy for Glycoproteomics: Identification of Glyco-Alteration Using Multiple Glycan Profiling Tools†

(2009) Hiromi Ito et al.   JOURNAL OF PROTEOME RESEARCH

Identification of an inducible factor secreted by pancreatic cancer cell lines that stimulates the production of fucosylated haptoglobin in hepatoma cells

(2008) Megumi Narisada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sugar Chains of Cerebrospinal Fluid Transferrin as a New Biological Marker of Alzheimer’s Disease

(2008) Miyako Taniguchi et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Site-specific analysis of N-glycans on haptoglobin in sera of patients with pancreatic cancer: A novel approach for the development of tumor markers

(2008) Miyako Nakano et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Glycan Structures in Animal Tissues

(2008) Alison V. Nairn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

(2008) Sanjay Sethi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation

(2008) James N. Arnold et al.   PROTEOMICS

Frontiers in glycomics: Bioinformatics and biomarkers in disease An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11–13, 2006)

(2007) Nicolle H. Packer et al.   PROTEOMICS