Recognition and Cleavage of Related to Ubiquitin 1 (Rub1) and Rub1-Ubiquitin Chains by Components of the Ubiquitin-Proteasome System

Structural and biochemical studies of the open state of Lys48-linked diubiquitin

(2012) Ming-Yih Lai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation

(2012) Susanne Bandau et al.   BMC BIOLOGY

Stress, specificity and the NEDD8 proteome

(2012) David P. Lane   CELL CYCLE

The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

(2012) Orsolya Leidecker et al.   CELL CYCLE

Regulation of parkin and PINK1 by neddylation

(2012) Y. S. Choo et al.   HUMAN MOLECULAR GENETICS

Rpn1 and Rpn2 Coordinate Ubiquitin Processing Factors at Proteasome

(2012) Rina Rosenzweig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neddylation positively regulates the ubiquitin E3 ligase activity of parkin

(2012) Ji Won Um et al.   JOURNAL OF NEUROSCIENCE RESEARCH

NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway

(2012) Willem den Besten et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

(2011) Roland Hjerpe et al.   BIOCHEMICAL JOURNAL

Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1

(2011) Tara A Gomez et al.   BMC BIOLOGY

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

(2011) Yu Ye et al.   EMBO REPORTS

Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease

(2011) Eric B. Dammer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome

(2011) Zanlin Yu et al.   MOLECULAR BIOLOGY OF THE CELL

The TFIIH Subunit Tfb3 Regulates Cullin Neddylation

(2011) Gwenaël Rabut et al.   MOLECULAR CELL

Constructing and decoding unconventional ubiquitin chains

(2011) Christian Behrends et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin: Same Molecule, Different Degradation Pathways

(2010) Michael J. Clague et al.   CELL

Another Tier for Caspase Regulation: IAPs as NEDD8 E3 Ligases

(2010) Sigi Benjamin et al.   DEVELOPMENTAL CELL

Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases

(2010) Meike Broemer et al.   MOLECULAR CELL

De novo structure generation using chemical shifts for proteins with high-sequence identity but different folds

(2010) Yang Shen et al.   PROTEIN SCIENCE

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

The mechanism of poly-NEDD8 chain formation in vitro

(2009) Yu Ohki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization

(2009) J. Merlet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The ubiquitin receptor Rad23: At the crossroads of nucleotide excision repair and proteasomal degradation

(2009) Nico P. Dantuma et al.   DNA REPAIR

Regulation of nucleolar signalling to p53 through NEDDylation of L11

(2009) Anders Sundqvist et al.   EMBO REPORTS

60th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkage

(2009) Yun-Seok Choi et al.   FEBS LETTERS

The proteasomal system

(2009) Tobias Jung et al.   MOLECULAR ASPECTS OF MEDICINE

Together, Rpn10 and Dsk2 Can Serve as a Polyubiquitin Chain-Length Sensor

(2009) Daoning Zhang et al.   MOLECULAR CELL

Targeting proteins for degradation

(2009) Erin K Schrader et al.   Nature Chemical Biology

Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains

(2009) Joshua J Sims et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An improved SUMmOn-based methodology for the identification of ubiquitin and ubiquitin-like protein conjugation sites identifies novel ubiquitin-like protein chain linkages

(2009) Stanley M. Jeram et al.   PROTEOMICS

Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1†‡

(2008) Judith Souphron et al.   BIOCHEMISTRY

Ribosomal proteins are targets for the NEDD8 pathway

(2008) Dimitris P Xirodimas et al.   EMBO REPORTS

Function and regulation of protein neddylation. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Gwénaël Rabut et al.   EMBO REPORTS

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

A Targeted Proteomic Analysis of the Ubiquitin-Like Modifier Nedd8 and Associated Proteins

(2008) Jeffrey Jones et al.   JOURNAL OF PROTEOME RESEARCH

Proteasome subunit Rpn13 is a novel ubiquitin receptor

(2008) Koraljka Husnjak et al.   NATURE

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2

(2008) Danny T Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Drosophila cbl Is Essential for Control of Cell Death and Cell Differentiation during Eye Development

(2008) Yuan Wang et al.   PLoS One

Consistent blind protein structure generation from NMR chemical shift data

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lost to translation: when autophagy targets mature ribosomes

(2008) Isabelle Beau et al.   TRENDS IN CELL BIOLOGY

Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin Chains

(2007) Daoning Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY