Regulation of parkin and PINK1 by neddylation

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

(2011) Dawn M. Wenzel et al.   NATURE

Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

(2011) Caroline Fernandes et al.   Molecular Brain

A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1

(2010) Hitoshi Murata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Genetics of Parkinson Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases

(2010) Meike Broemer et al.   MOLECULAR CELL

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

(2009) Hui Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification

(2009) Danny T. Huang et al.   MOLECULAR CELL

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies

(2009) Selvaraju Veeriah et al.   NATURE GENETICS

The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes

(2009) N. Meyer-Schaller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in the GIGYF2 (TNRC15) Gene at the PARK11 Locus in Familial Parkinson Disease

(2008) Corinne Lautier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

(2008) Coro Paisan-Ruiz et al.   ANNALS OF NEUROLOGY

Novel substrates and functions for the ubiquitin-like molecule NEDD8: Figure 1

(2008) Dimitris P. Xirodimas   BIOCHEMICAL SOCIETY TRANSACTIONS

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

(2008) David M. Duda et al.   CELL

Ribosomal proteins are targets for the NEDD8 pathway

(2008) Dimitris P Xirodimas et al.   EMBO REPORTS

Can overexpression of parkin provide a novel strategy for neuroprotection in Parkinson's disease?

(2008) Ayse Ulusoy et al.   EXPERIMENTAL NEUROLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Dcn1 Functions as a Scaffold-Type E3 Ligase for Cullin Neddylation

(2008) Thimo Kurz et al.   MOLECULAR CELL

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

(2008) H. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA