Deletion of Cysteine Cathepsins B or L Yields Differential Impacts on Murine Skin Proteome and Degradome

Comparative Large Scale Characterization of PlantversusMammal Proteins Reveals Similar and IdiosyncraticN-α-Acetylation Features

(2012) Willy V. Bienvenut et al.   MOLECULAR & CELLULAR PROTEOMICS

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

(2011) Stefan Tholen et al.   BIOLOGICAL CHEMISTRY

Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites

(2011) Oliver Schilling et al.   BIOLOGICAL CHEMISTRY

Periostin in fibrillogenesis for tissue regeneration: periostin actions inside and outside the cell

(2011) Akira Kudo   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein alpha-N-acetylation studied by N-terminomics

(2011) Petra Van Damme et al.   FEBS Journal

Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S

(2011) Martin L. Biniossek et al.   JOURNAL OF PROTEOME RESEARCH

Protective role of cathepsin L in mouse skin carcinogenesis

(2011) Fernando Benavides et al.   MOLECULAR CARCINOGENESIS

Interactions between cancer stem cells and their niche govern metastatic colonization

(2011) Ilaria Malanchi et al.   NATURE

TopFIND, a knowledgebase linking protein termini with function

(2011) Philipp F Lange et al.   NATURE METHODS

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates

(2011) Oded Kleifeld et al.   Nature Protocols

Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry

(2011) Oliver Schilling et al.   Nature Protocols

Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis

(2011) Hsien-Yi Lin et al.   PLoS One

Impaired turnover of autophagolysosomes in cathepsin L deficiency

(2010) Julia Dennemärker et al.   BIOLOGICAL CHEMISTRY

WaveletQuant, an improved quantification software based on wavelet signal threshold de-noising for labeled quantitative proteomic analysis

(2010) Fan Mo et al.   BMC BIOINFORMATICS

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea

(2010) Patrick L. J. M. Zeeuwen et al.   FASEB JOURNAL

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

(2010) V. Gocheva et al.   GENES & DEVELOPMENT

Dermokine as a novel biomarker for early-stage colorectal cancer

(2010) Tomoyuki Tagi et al.   JOURNAL OF GASTROENTEROLOGY

Profiling ofN-Acetylated Protein Termini Provides In-depth Insights into the N-terminal Nature of the Proteome

(2010) Andreas O. Helbig et al.   MOLECULAR & CELLULAR PROTEOMICS

Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics

(2010) Anna Prudova et al.   MOLECULAR & CELLULAR PROTEOMICS

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

(2010) L Sevenich et al.   ONCOGENE

VEGF-A Induces Angiogenesis by Perturbing the Cathepsin-Cysteine Protease Inhibitor Balance in Venules, Causing Basement Membrane Degradation and Mother Vessel Formation

(2009) S.-H. Chang et al.   CANCER RESEARCH

The Biology of Cystatin M/E and its Cognate Target Proteases

(2009) Patrick L.J.M. Zeeuwen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

(2009) Paul J Boersema et al.   Nature Protocols

MEROPS: the peptidase database

(2009) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

(2009) J Dennemärker et al.   ONCOGENE

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

(2009) T. Arnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

(2009) Sandra Goetze et al.   PLOS BIOLOGY

Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy

(2008) Xin Zheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ProteoWizard: open source software for rapid proteomics tools development

(2008) Darren Kessner et al.   BIOINFORMATICS

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression

(2008) Lydiane Funkelstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling

(2008) Qizhu Tang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions

(2008) Cuiping Pan et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

(2008) O Vasiljeva et al.   ONCOGENE

Sequence requirements for Nα‐terminal acetylation of yeast proteins by NatA

(2008) Michel Perrot et al.   YEAST