Article
Chemistry, Analytical
Yi Duan, Chuanliang Wang, Xuhui Geng, Guiqiu Wang, Yafeng Guan
Summary: A highly sensitive optical fiber-based laser-induced fluorescence (LIF) detector was developed for in-vitro parathyroid gland (PG) identification. By designing a special optical fiber probe and adding a dichroic mirror module, the sensitivity was increased and the noise was reduced, leading to more accurate detection results.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Electrical & Electronic
Jiacheng Sun, Tao Wang, Zeinab Jafari, Fei Gao, Xiao Lin, Hongsheng Chen, Gaofeng Wang, Israel De Leon
Summary: Plasmonic lasers provide a paradigm-changing approach for generating coherent light at the nanoscale, with high sensitivity to the surrounding environment for potential use in high-performance sensing devices. The proposed plasmonic laser architecture based on a high-Q plasmonic crystal shows excellent surface sensing properties, surpassing previously reported high-performance plasmonic biosensor architectures.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Article
Biophysics
Qiao Zhao, Yongchun Pan, Xiaowei Luan, Yanfeng Gao, Xiaozhi Zhao, Yinghui Liu, Yuzhen Wang, Yujun Song
Summary: The research utilized nanotechnology to activate the trans-cleavage activity of CRISPR/Cas12a, establishing a universal signal transduction strategy for detecting protein biomarkers with higher sensitivity and wider range than traditional methods.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Yongjun Bian, Mengwei Li, Zhaojie Wu, Jian Weng, Ru Zeng, Liping Sun
Summary: Researchers have developed an ultrasensitive fluorescent biosensor using sporopollenin capsules as a substrate for isothermal amplification. This biosensor can detect miRNA with a low detection limit and a wide linear range, and it shows high selectivity and minimal interference from serum proteins.
Article
Biophysics
Yongqiang Shi, Lei Lin, Yuzhen Wei, Wenting Li, Pengcheng Nie, Yong He, Xuping Feng
Summary: A novel ratiometric aptasensor was developed using CQDs@ZIF8 and Apt-AuNPs for highly sensitive detection of ABA. The sensor showed increased sensitivity and selectivity in detecting ABA levels in rice seeds, offering a new strategy for ultra-sensitive measurement of biomolecules.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Engineering, Electrical & Electronic
Chien-Ming Chen, Ya-Li Tsai
Summary: A novel fluorescence-based bioassay for rapid and cost-effective detection of rat creatinine concentration was developed. The fluorescence intensity was used to calculate the creatinine concentration, and a fluorescence sensing system was established.
IEEE SENSORS JOURNAL
(2022)
Article
Engineering, Environmental
Yongqiang Shi, Qicong Wu, Wenting Li, Lei Lin, Fangfang Qu, Chenjia Shen, Yuzhen Wei, Pengcheng Nie, Yong He, Xuping Feng
Summary: A flower-shaped fluorescent probe for hydrogen peroxide (H2O2) and levofloxacin (LVF) sensing was developed based on MoOx QDs@Co/Zn-MOFs with porous structure, showing promising results for trace H2O2 and LVF monitoring in eco-environment. The combination of MoOx QDs and Co/Zn-MOFs exhibited peroxidase-like properties and greatly enhanced synergistic catalytic capabilities. The probe efficiently catalyzed H2O2 to produce ·OH and was able to detect LVF with low detection limits.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Wei Wang, Pengyin Deng, Xiqing Liu, Yuqin Ma, Yongsheng Yan
Summary: A hydrophobicity fluorescence sensor based on CsPbBr3 QDs and Boron Nitride was constructed for sensitive detection of tetracycline abuse, with a linear range of 0-0.44 mg L-1 and a detection limit of 6.5 μg L-1. The sensor successfully recognized tetracycline in honey and milk samples, providing an ideal for designing CsPbBr3 QDs-based fluorescence sensors.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Martin Paul, Robert Tannenberg, Georg Tscheuschner, Marco Ponader, Michael G. Weller
Summary: The article introduces an immunoassay sensor based on a monolithic affinity column, which can detect trace amounts of cocaine in a short time with high sensitivity and rapid detection capability. This technology has important application value in drug smuggling control and other fields.
Article
Chemistry, Analytical
Hak-Sung Jung, Junsang Cho, Keir C. Neuman
Summary: Latent fingerprints are crucial evidence in crime scenes, and an efficient method for detecting them is important in forensic science. This study introduces a new method using stable CsPbBr3 perovskite nanocrystals to develop latent fingerprints on diverse surfaces, providing high resolution images with unique friction ridge arrangements.
ANALYTICA CHIMICA ACTA
(2021)
Article
Multidisciplinary Sciences
Youhee Heo, Kwanwoo Shin, Min Cheol Park, Ji Yoon Kang
Summary: This report introduces a method for enhancing the sensitivity of chemifluorescence-based ELISA, using photooxidation-induced fluorescence amplification (PIFA). PIFA utilizes autocatalytic photooxidation to amplify the fluorescent product, improving detection sensitivity. The method requires minimal modifications to the fluorescence reader and is compatible with conventional ELISA assays.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Yao Mi, Yufei Ma
Summary: This paper presents an ultra-highly sensitive ammonia sensor using the LITES technique, achieving a minimum detection limit (MDL) of approximately 5.85 ppm by optimizing the wavelength modulation depth.
Article
Chemistry, Analytical
Jinlan Yang, Jingwen Huang, Jing Huang, Li Yang
Summary: The development of optical fiber-based biosensors is driven by the increasing demand for simple, rapid, and miniaturized analytical devices for accurate and sensitive detection of biomolecules. This study presents a micro-structured optical fiber (MSOF)-based biosensor for ultra-sensitive analysis of O-GlcNAc transferase (OGT). The biosensor shows an ultralow limit-of-detection and has demonstrated feasibility for clinical application in sensitive diagnosis of OGT.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Physical
Lingjun Zhang, Jianfeng Sun, Yurui Fang, Yingzhou Huang, Hengyu Guo, Zhong Lin Wang
Summary: This study introduces an ultrasensitive SERS detection system using electrokinetic preconcentration with a triboelectric nanogenerator, which significantly enhances the efficiency of enriching target molecules on the substrate.
Article
Chemistry, Analytical
Myeong-Jun Lee, Ji-Ae Song, Jin-Ha Choi, Jeong-Hyeop Shin, Ji-Woon Myeong, Ki-Ppeum Lee, Taehwan Kim, Ki-Eob Park, Byung-Keun Oh
Summary: Hydrogen peroxide (H2O2) has been widely studied in various fields and several types of fluorescent protein-stabilized gold nanoclusters have been developed for its detection. However, the sensitivity of these methods is low. To overcome this, a horseradish peroxidase-encapsulated fluorescent bio-nanoparticle (HEFBNP) was developed, which showed high sensitivity and selectivity in detecting H2O2.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)