Article
Chemistry, Analytical
Wen Zeng, Zenghui Hu, Jin Luo, Xiandeng Hou, Xiaoming Jiang
Summary: The method proposed a highly sensitive determination of trace antimony using cobalt ion enhanced PCVG for sample introduction into AFS or ICP-MS. By optimizing the experimental conditions, including enhancement ions, acid medium, UV irradiation, working gas, and potential interference, the method achieved low detection limits and satisfactory recoveries in the analysis of real water samples.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Yongchun Liu, Jie Zou, Bin Luo, Hairong Yu, Zhigang Zhao, Hui Xia
Summary: Using natural plant extracts as auxiliary matrix or photocatalysts can enhance the efficiency and sensitivity of photochemical vapor generation atomic fluorescence spectrometry for trace mercury determination, while reducing biological toxicity and secondary pollution. This green and sensitive method provides an experimental basis for expanding the photochemical vapor generation system.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Lanlan Li, Qirui Huang, Jing Xiao, Jiamin Feng, Shu Zhang, Hong Luo, Zhirong Zou, Xiaoli Xiong
Summary: In this study, Fe3O4 served as both an adsorbent and photocatalyst in the photochemical vapor generation-atomic fluorescence spectrometry (PVG-AFS) determination of Bi(III) after preconcentration. The effects of formic and acetic acid concentration, UV irradiation time, Fe3O4 concentration, and interferences from co-existing ions were investigated. Results showed that the AFS intensity was slightly enhanced by the mixed acid solution, but a significant enhancement was observed when Fe3O4 was used as a photocatalyst. Fe3O4 can decompose in the mixed acid solution, generating Fe3+ which acts as a sensitizer for improving Bi(III) efficiency. Under optimized conditions, the LOD of the proposed PVG-AFS system with or without preconcentration (5 mL sample) were 0.44 ng/mL and 0.07 ng/mL, respectively. The PVG-AFS system was successfully applied to the determination of water samples and demonstrated good accuracy and applicability with recoveries ranging from 94% to 104%.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Jaromir Vyhnanovsky, Dilek Yildiz, Barbora Stadlerova, Stanislav Musil
Summary: The study achieved photochemical vapor generation of bismuth with optimal conditions determined through investigating the influence of sensitizers and reaction medium flow rate. Combining PVG with atomic fluorescence spectrometry can provide low limits of detection at a low operation cost.
MICROCHEMICAL JOURNAL
(2021)
Review
Instruments & Instrumentation
Yafei Zhen, Hanjiao Chen, Meng Zhang, Jing Hu, Xiandeng Hou
Summary: The study presents a method for enhancing the sensitive determination of rhenium by improving PVG efficiency using Cd2+ and Co2+, leading to a lower LOD under specific conditions.
APPLIED SPECTROSCOPY REVIEWS
(2022)
Article
Chemistry, Analytical
Eva Jenikova, Eliska Novakova, Jakub Hranicek, Stanislav Musil
Summary: Photochemical vapor generation (PVG) of Te4+ was achieved using a simple reactor and investigated for its application in the determination of Te in water samples. The study explored the composition of the reaction medium, the irradiation time, and the effects of sensitizers and interferents. The results showed that PVG could be used for sensitive determination of Te in water samples under optimized conditions.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Yuheng Lu, Chenghui Li, Yunfei Tian, Jing Hu, Xiandeng Hou
Summary: The highly sensitive detection of trace tellurium (Te(IV)) in real samples with complicated matrix was achieved by using a new method based on photochemical vapor generation-atomic fluorescence spectrometry (PVG-AFS) and Co-MOF-74 as an adsorbent and Co2+ ion sensitizer. The synthesized Co-MOF-74 showed excellent adsorption capability for Te(IV) within a short time. After conversion to volatile compounds under UV irradiation, the Te(IV) was detected by AFS. The proposed method exhibited a limit of detection of 0.08 ng/mL for Te(IV) after a 50-fold preconcentration and was successfully applied to the analysis of various natural water samples with satisfactory spike recoveries.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Haiyan Yang, Kejun Li, Yanping Wang, Xin Yuan, Mei Zhang
Summary: A simple and label-free method was developed for hydrogen peroxide (H2O2) assay by chemical vapor generation-atomic fluorescence spectrometry. The method is based on the inhibition of the atomic fluorescence signal of As(III) by L-Cysteine (L-Cys) and the oxidation of L-Cys to cystine by H2O2 and I-. The proposed method has the advantages of simplicity and cost-effectiveness.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Lanlan Li, Chenxi Jiang, Jing Xiao, Hong Luo, Shu Zhang, Zhirong Zou, Ke Huang
Summary: Selenium, mercury and arsenic are widely distributed in the environment, and their toxicity depends on their concentration and forms. Accurate monitoring of these elements is necessary. Photochemical vapor generation (PVG) is a promising method for analytical atomic spectrometry, and it has been applied to determine selenium, mercury and arsenic with various separation techniques. This review summarizes the applications of PVG-analytical atomic spectrometry in selenium, mercury and arsenic speciation analysis.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Review
Chemistry, Analytical
Guanghui Niu, Alexander Knodel, Sebastian Burhenn, Sebastian Brandt, Joachim Franzke
Summary: The development of miniature, sensitive, high throughput, and in-situ analytical instruments using dielectric barrier discharge (DBD) has become a hot topic in modern analytical chemistry. DBD offers advantages such as easy operation, simple configuration, ambient working temperature and pressure, low power consumption, and miniature dimension. Its applications in analytical atomic spectrometry include serving as excitation or atomization sources in AES, AAS, and AFS, as well as functioning as a vapor generation system.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Yubin Su, Yao Lin, Rui Yang, Liangbo He, Jiahui Yang, Xiaoming Jiang, Chengbin Zheng
Summary: A versatile high-throughput photochemical reactor was developed for the rapid and sensitive determination of mercury, nickel, and selenium. By coupling photochemical vapor generation (PVG) to atomic fluorescence spectrometry (AFS) or point discharge optical emission spectrometry (μPD-OES), the reactor achieved high throughput, high sensitivity, and eliminated interference from transition metal ions. The practicality of the reactor was demonstrated through successful detection in various certified reference materials.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Liang Dong, Hanjiao Chen, Yongyan Ning, Yaowen He, Ying Yu, Ying Gao
Summary: Photochemical vapor generation (PVG) is an alternative sample introduction method in atomic spectrometry, and the addition of transition metals can enhance its efficiency. This study introduced vanadium species as novel sensitizers in PVG and applied it for the determination of tellurium.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Linda Sagapova, Stanislav Musil, Barbora Kodrikova, Milan Svoboda, Jan Kratzer
Summary: By studying the effect of modifiers, it was found that the Cr3+/KCn and Ti4+/KCn environments exhibited higher CVG efficiency and sensitivity, while the Co2+/ascorbic acid/thiourea environment showed lower efficiency.
ANALYTICA CHIMICA ACTA
(2021)
Article
Engineering, Multidisciplinary
Cagdas Buyukpinar, Suleyman Bodur, Elif Yazici, Zeynep Tekin, Nevim San, Okan Tarik Komesli, Sezgin Bakirdere
Summary: An eco-friendly and accurate analytical protocol was proposed for the determination of trace levels of cadmium in this study. By combining PVG and T-SQT-AT techniques, the analytical performance of the system was enhanced, with good recovery results obtained in tap water and daphne tea samples.
Article
Biochemical Research Methods
Ying Yu, Jiaju Hu, Xinyi Zhao, Jiangchuan Liu, Ying Gao
Summary: Photochemical vapor generation (PVG) of germanium (Ge) was first reported in this work. The synergistic effect from cobalt/chloride ions and air-liquid interfaces was found to enhance the PVG of Ge. The study also investigated the PVG mechanism of Ge and explored its potential applications.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Instruments & Instrumentation
Ziyan Li, Rui Liu, Yi Lv
Summary: This review discusses the progress of ICPMS in multiplex bioassay, including various biomarkers and methodological innovations. The limitations are summarized and prospects are proposed for the emergence of more powerful and application-oriented analytical methods.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Chemistry, Analytical
Chaoqun Wang, Hongjie Song, Xin Zhao, Rui Liu, Yi Lv
Summary: Biomimetic DNA walking machines have shown success in exploring the microscopic world and sensitive biosensing of disease biomarkers. This study presents multiplexing three-dimensional DNA walking machines for lung cancer-associated miRNA detection based on HR-ICPMS, demonstrating satisfactory analysis capabilities for complex biological samples.
ANALYTICAL CHEMISTRY
(2022)
Review
Instruments & Instrumentation
Sirui Pu, Yi Pan, Lichun Zhang, Yi Lv
Summary: The emission of volatile sulfur compounds (VSCs) poses risks to the environment, product quality, and human health. Establishing sensitive and convenient analytical methods for VSCs detection is of great importance. Chemiluminescence (CL) and cataluminescence (CTL) offer promising techniques for VSCs detection due to their fast response, high sensitivity, and simplicity. CL analysis has been widely applied in various fields using auxiliary CL methods and sulfur chemiluminescence detector (SCD), while CTL detection is prosperous in the construction of gas sensors, including the exploration of sensing materials and detection modes.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Spectroscopy
Ziqiang Deng, Jianyu Hu, Rui Liu, Yi Lv
Summary: The CRISPR/Cas biosensing method proposed in this study allows for highly sensitive and specific detection of Tobramycin (TOB) through the combination of aptamer recognition and element labeling strategy. This method has been successfully applied in the analysis of actual water samples.
ATOMIC SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yan Li, Zili Huang, Ziyan Li, Caixia Li, Rui Liu, Yi Lv
Summary: The occurrence of cancers often involves abnormal expression of biomarkers. This study proposes a simple and sensitive mass spectrometric method for multiplex detection of nucleic acids and proteins, which could be potentially useful for rapid cancer screening.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jiaxi Hu, Cheng Chen, Xiaobin Xie, Lichun Zhang, Hongjie Song, Yi Lv
Summary: In response to the increasing threat of explosive-based terrorism and environmental concerns, a reliable and easy-to-use cataluminescence sensor system has been developed for the rapid and accurate detection of six types of military explosive vapors. The sensor device and detection platform constructed in this research provide a new sensing principle for the efficient identification of explosives.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Qiuyan Li, Shuguang Yan, Hongjie Song, Yingying Su, Mingxia Sun, Yi Lv
Summary: In this study, a Ce(IV)-MOF structure with high selectivity and stability in chemiluminescence reaction was fabricated, leading to the successful establishment of a simple, stable, and sensitive fluorescent sensing platform for SO32-.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Suqin Xiong, Shuguang Yan, Mingxia Sun, Hongjie Song, Lichun Zhang, Jiaxi Hu, Yi Lv
Summary: This study modulated the nitrogen vacancy content in g-C3N4 by changing the temperature of secondary calcination. It was found that nitrogen vacancy significantly enhanced the cataluminescence intensity of ammonium sulfide. Furthermore, a CN-600-based sensor with excellent selectivity and stability was developed for the detection of ammonium sulfide.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Mingxia Sun, Hongjie Song, Haiyi Liu, Yingying Su, Xiaobo Xie, Yi Lv
Summary: This study proposes a mild chemiluminescence system for detecting sulfite under neutral conditions. By activating sulfite and enhancing the generation of SO3-, a strong chemiluminescence signal is generated with the aid of APDI NSs. The developed method provides a sensitive and selective platform for sulfite detection.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zixuan Zhan, Li Chai, Haihui Yang, Yongcheng Dai, Zeliang Wei, Denian Wang, Yi Lv
Summary: In this study, a unique two-photon fluorescent probe (ER-ONOO-) was developed to detect ONOO- in aqueous solution with high sensitivity, high selectivity, and ultrafast response time. The probe successfully evaluated the levels of ONOO- at the endoplasmic reticulum (ER) in a hypoxia-induced endothelial injury model. Furthermore, it was able to monitor the changes in organ fluorescence through ONOO- variation in different stages of a cecum ligation and puncture (CLP) mouse model. The study confirmed the involvement of endoplasmic reticulum stress and oxidative stress in the CLP model, providing a reliable tool for studying ONOO- fluctuation in sepsis and offering new insights into the pathogenic and therapeutic mechanisms involved.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yao Lin, Yuyang Li, Hongqi Chang, Simin Ye, Yi Ye, Lin Yang, Linchuan Liao, Hao Dai, Zeliang Wei, Yurong Deng, Jinyi Zhang, Chengbin Zheng
Summary: The excessive consumption of THC poses severe health risks and public safety concerns. However, the quantification of THC using simple and cost-effective tools remains challenging. In this study, researchers developed a label-free ratiometric fluorescent sensor based on THC1.2/ThT and red CdTe quantum dots for the instant monitoring of THC and its metabolite THC-COOH.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yongcheng Dai, Jing Zhou, Chudong Wei, Li Chai, Xiaobo Xie, Rui Liu, Yi Lv
Summary: This study established a multiplexing LC-MS workflow for simultaneous detection of nitric oxide (NO) and various metabolites in cells. The method, based on a novel iridium signature mass spectrometric probe, showed high accuracy and sensitivity in detecting NO. It also revealed the effects of different NO concentrations on cellular metabolites.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yanyan Zhang, Mingxia Sun, Xiaohan Yuan, Chudong Wei, Yingying Su, Yi Lv
Summary: In recent years, the use of advanced oxidation processes (AOPs) based on peracetic acid (PAA) has gained attention for its high oxidative potential and low byproduct formation. However, there is still a need to study the activation of PAA and the degradation mechanism to develop more efficient and stable PAA-based AOPs. This study investigates a new PAA-based AOP activated by metal-organic framework-derived cobalt phosphide (CoP) and accompanied by chemiluminescence (CL) behavior. The CoP/PAA system showed efficient degradation of RhB, with a degradation rate 23.7 times higher than that of the conventional Co3O4/PAA system, and the degradation process was confirmed to be driven by O-1(2).
Article
Chemistry, Analytical
Xiaohan Yuan, Shuguang Yan, Chudong Wei, Yanyan Zhang, Yingying Su, Yi Lv
Summary: In this study, nitrogen-doped carbon dots (N-CDs) were found to significantly enhance the chemiluminescence (CL) intensity of the Ce (IV)-Na2S system. The mechanism was explored and discussed through experiments with free radical scavengers, CL spectra, and X-ray photoelectron spectroscopy (XPS). The enhancement is mainly attributed to the chemiluminescence resonance energy transfer (CRET) between (1O2)2*/Ce (III)* and N-CDs, where mono-dispersed N-CDs catalyze the production of more 1O2 on their surface. The new CL system was successfully utilized for the detection of H2S with a linear range of 20-200 nM and a limit of detection (LOD) of 0.32 nM. The system also demonstrated good recovery rates in different water samples, making it a promising platform for practical applications.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Ziyan Li, Jing Zhou, Chaoqun Wang, Rui Liu, Jianyu Hu, Yi Lv
Summary: The study presents a triplevalent tetrahedral DNA nanostructure (tTDN) with three overhang isotope probes capable of multiplex simultaneous analysis for accurate and cost-effective detection of different variants of SARS-CoV-2. Using the TDN scaffold and MNAzyme system, the study successfully identified and screened four different variants of concern (VOC) associated with α, β, δ, and Ο, with common mutations in the S gene.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
