The diversity of receptor recognition in cholesterol-dependent cytolysins

Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59

(2013) Steven Johnson et al.   Cell Reports

Export Requirements of Pneumolysin in Streptococcus pneumoniae

(2012) K. E. Price et al.   JOURNAL OF BACTERIOLOGY

Listeriolysin O: the Swiss army knife of Listeria

(2012) Mélanie Anne Hamon et al.   TRENDS IN MICROBIOLOGY

The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly

(2012) Kelley J. Dowd et al.   PLoS Pathogens

Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor

(2011) HISASHI OHKUNI et al.   APMIS

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mapping the Intermedilysin-Human CD59 Receptor Interface Reveals a Deep Correspondence with the Binding Site on CD59 for Complement Binding Proteins C8α and C9

(2011) Stephanie E. Wickham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes

(2011) Stephen Vadia et al.   PLoS Pathogens

Role of pneumococcal pneumolysin in the induction of an inflammatory response in human epithelial cells

(2010) In-Hwa Yoo et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

MKP1 regulates the induction of inflammatory response by pneumococcal pneumolysin in human epithelial cells

(2010) Hee-Sung Shin et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1  Secretion in Macrophages Infected with Listeria monocytogenes

(2010) S. R. Dewamitta et al.   INFECTION AND IMMUNITY

Specific Behavior of IntracellularStreptococcus pyogenesThat Has Undergone Autophagic Degradation Is Associated with Bacterial Streptolysin O and Host Small G Proteins Rab5 and Rab7

(2010) Atsuo Sakurai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

(2010) A. J. Farrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Streptococcus pneumoniaeevades human dendritic cell surveillance by pneumolysin expression

(2009) Marie Littmann et al.   EMBO Molecular Medicine

Intermedilysin-Receptor Interactions during Assembly of the Pore Complex

(2009) Stephanie LaChapelle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF- B Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor

(2009) J. Harder et al.   JOURNAL OF IMMUNOLOGY

Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59

(2009) Timothy R. Hughes et al.   MOLECULAR IMMUNOLOGY

Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice

(2009) Mark C. Dessing et al.   PLoS One

Characterization of a Streptococcal Cholesterol-Dependent Cytolysin with a Lewis y and b Specific Lectin Domain†

(2008) Stephen Farrand et al.   BIOCHEMISTRY

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE

Critical Involvement of Pneumolysin in Production of Interleukin-1  and Caspase-1-Dependent Cytokines in Infection with Streptococcus pneumoniae In Vitro: a Novel Function of Pneumolysin in Caspase-1 Activation

(2008) S. Shoma et al.   INFECTION AND IMMUNITY

Functional and Phylogenetic Characterization of Vaginolysin, the Human-Specific Cytolysin from Gardnerella vaginalis

(2008) S. E. Gelber et al.   JOURNAL OF BACTERIOLOGY

Streptolysin O Promotes Group AStreptococcusImmune Evasion by Accelerated Macrophage Apoptosis

(2008) Anjuli M. Timmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY