Metallomics for drug development: an integrated CE-ICP-MS and ICP-MS approach reveals the speciation changes for an investigational ruthenium(iii) drug bound to holo-transferrin in simulated cancer cytosol

X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019)

(2013) Alfred A. Hummer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Redox activation of metal-based prodrugs as a strategy for drug delivery

(2012) Nora Graf et al.   ADVANCED DRUG DELIVERY REVIEWS

Proteomic and Metallomic Strategies for Understanding the Mode of Action of Anticancer Metallodrugs

(2012) Chiara Gabbiani et al.   Anti-Cancer Agents in Medicinal Chemistry

Element Speciation Analysis Using Capillary Electrophoresis: Twenty Years of Development and Applications

(2012) Andrei R. Timerbaev   CHEMICAL REVIEWS

Analytical Approaches for Assaying Metallodrugs in Biological Samples: Recent Methodological Developments and Future Trends

(2012) Andrei Timerbaev et al.   CURRENT DRUG METABOLISM

Distinct cellular fates for KP1019 and NAMI-A determined by X-ray fluorescence imaging of single cells

(2012) Jade B. Aitken et al.   Metallomics

Advances of CE-ICP-MS in speciation analysis related to metalloproteomics of anticancer drugs

(2012) Andrei R. Timerbaev et al.   TALANTA

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

(2011) Alberta Bergamo et al.   DALTON TRANSACTIONS

Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019

(2011) Caroline Bartel et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Metall(prote)omic studies by capillary electrophoresis using separation capillary as an in-line reactor

(2011) Andrei R. Timerbaev et al.   Metallomics

Recent progress in the application of analytical techniques to anticancer metallodrug proteomics

(2011) A.R. Timerbaev et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Ruthenium-based chemotherapeutics: are they ready for prime time?

(2010) Emmanuel S. Antonarakis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study

(2009) Frederike Lentz et al.   ANTI-CANCER DRUGS

A categorization of metal anticancer compounds based on their mode of action

(2009) Teresa Gianferrara et al.   DALTON TRANSACTIONS

Recent developments in ruthenium anticancer drugs

(2009) Aviva Levina et al.   Metallomics

Capillary electrophoresis coupled to mass spectrometry for biospeciation analysis: critical evaluation

(2009) A.R. Timerbaev   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma

(2008) Michael Groessl et al.   ELECTROPHORESIS

Application of capillary electrophoresis–inductively coupled plasma mass spectrometry to comparative studying of the reactivity of antitumor ruthenium(III) complexes differing in the nature of counter-ion toward human serum proteins

(2008) Kasia Połeć-Pawlak et al.   JOURNAL OF CHROMATOGRAPHY A

CE-ICP-MS for studying interactions between metals and biomolecules

(2008) Xue-Bo Yin et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY