Metal imaging in neurodegenerative diseases

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

(2017) Joanna F. Collingwood et al.   JOURNAL OF ALZHEIMERS DISEASE

Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis

(2017) Sandro Altamura et al.   JOURNAL OF ALZHEIMERS DISEASE

A Copper-Lowering Strategy Attenuates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2017) Joseph F. Quinn et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

(2017) Mark A. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

Bis (thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease

(2017) Michelle T. Fodero-Tavoletti et al.   JOURNAL OF ALZHEIMERS DISEASE

A turning point for Alzheimer's disease?

(2012) Jack C. de la Torre   BIOFACTORS

Late-onset Patients with Sporadic Amyotrophic Lateral Sclerosis in Japan have a Higher Progression Rate of ALSFRS-R at the Time of Diagnosis

(2012) Yuji Tanaka et al.   INTERNAL MEDICINE

The distribution profile and oxidation states of biometals in APP transgenic mouse brain: dyshomeostasis with age and as a function of the development of Alzheimer's disease

(2012) Huajian Wang et al.   Metallomics

Alzheimer’s Disease in the Retina: Imaging Retinal Aß Plaques for Early Diagnosis and Therapy Assessment

(2012) Yosef Koronyo et al.   Neurodegenerative Diseases

Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model

(2012) T. Hirayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular imaging with optical coherence tomography using ligand-conjugated microparticles that detect activated endothelial cells: Rational design through target quantification

(2011) Andrew Jefferson et al.   ATHEROSCLEROSIS

Calreticulin Inhibits Prion Protein PrP-(23–98) Aggregationin Vitro

(2011) Noriyuki SHIRAISHI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

One Octarepeate Expansion to the Human Prion Protein Alters Both the Zn2+and Cu2+Coordination Environments within the Octarepeate Domain

(2011) Jason Shearer et al.   INORGANIC CHEMISTRY

The Role of Molecular Imaging in the Diagnosis and Management of Neuropsychiatric Disorders

(2011) Lie-Hang Shen et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Prion protein expression level alters regional copper, iron and zinc content in the mouse brain

(2011) M. Jake Pushie et al.   Metallomics

Evaluation of striatal oxidative stress in patients with Parkinson's disease using [62Cu]ATSM PET

(2011) Masamichi Ikawa et al.   NUCLEAR MEDICINE AND BIOLOGY

Imaging methods for elemental, chemical, molecular, and morphological analyses of single cells

(2010) Cyril Petibois   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Fourier Transform Infrared Imaging Showing Reduced Unsaturated Lipid Content in the Hippocampus of a Mouse Model of Alzheimer’s Disease

(2010) Andreana C. Leskovjan et al.   ANALYTICAL CHEMISTRY

Characterizing iron deposition in Parkinson's disease using susceptibility-weighted imaging: An in vivo MR study

(2010) Jiuquan Zhang et al.   BRAIN RESEARCH

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

The transition metals copper and iron in neurodegenerative diseases

(2010) Susana Rivera-Mancía et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice

(2010) L. Wang et al.   HUMAN MOLECULAR GENETICS

Copper and Zinc Metallation Status of Copper-Zinc Superoxide Dismutase from Amyotrophic Lateral Sclerosis Transgenic Mice

(2010) Herman L. Lelie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Trace metal imaging with high spatial resolution: Applications in biomedicine

(2010) Zhenyu Qin et al.   Metallomics

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Early Detection of Alzheimer’s Disease with PET Imaging

(2010) V. Berti et al.   Neurodegenerative Diseases

Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease

(2010) Andreana C. Leskovjan et al.   NEUROIMAGE

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations

(2010) D. Baumer et al.   NEUROLOGY

Pigmented creatine deposits in Amyotrophic Lateral Sclerosis central nervous system tissues identified by synchrotron Fourier Transform Infrared microspectroscopy and X-ray fluorescence spectromicroscopy

(2010) M.Z. Kastyak et al.   NEUROSCIENCE

Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

(2010) James A. Duce et al.   PROGRESS IN NEUROBIOLOGY

New mass spectrometric tools in brain research

(2010) J. Sabine Becker et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

(2009) Eric G. Solon et al.   AAPS Journal

Manganese Accumulates within Golgi Apparatus in Dopaminergic Cells as Revealed by Synchrotron X-ray Fluorescence Nanoimaging

(2009) Asunción Carmona et al.   ACS Chemical Neuroscience

Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: A systematic review

(2009) Nadia A. Sutedja et al.   Amyotrophic Lateral Sclerosis

A novel approach to the identification and quantitative elemental analysis of amyloid deposits—Insights into the pathology of Alzheimer’s disease

(2009) Reshmi Rajendran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantitative imaging of metals in tissues

(2009) Martina Ralle et al.   BIOMETALS

Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential

(2009) Laetitia Mony et al.   BRITISH JOURNAL OF PHARMACOLOGY

In Situ Imaging of Metals in Cells and Tissues

(2009) Reagan McRae et al.   CHEMICAL REVIEWS

Copper in the brain and Alzheimer’s disease

(2009) Ya Hui Hung et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer’s disease

(2009) Sakae Yumoto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis?

(2009) Donna W. Lee et al.   JOURNAL OF NEUROCHEMISTRY

Cerebral bioimaging of Cu, Fe, Zn, and Mn in the MPTP mouse model of Parkinson’s disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)

(2009) Andreas Matusch et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Bio-metals imaging and speciation in cells using proton and synchrotron radiation X-ray microspectroscopy

(2009) R. Ortega et al.   Journal of the Royal Society Interface

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Zinc in the physiology and pathology of the CNS

(2009) Stefano L. Sensi et al.   NATURE REVIEWS NEUROSCIENCE

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

(2009) Pier Giorgio Mastroberardino et al.   NEUROBIOLOGY OF DISEASE

Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease

(2009) Andreana C. Leskovjan et al.   NEUROIMAGE

Mapping metals in Parkinson's and normal brain using rapid-scanning x-ray fluorescence

(2009) Bogdan F Gh Popescu et al.   PHYSICS IN MEDICINE AND BIOLOGY

Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques

(2008) A. Carmona et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The chemistry of copper binding to PrP: is there sufficient evidence to elucidate a role for copper in protein function?

(2008) Paul Davies et al.   BIOCHEMICAL JOURNAL

Imaging neurodegeneration in Parkinson's disease

(2008) Nicola Pavese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer’s disease

(2008) Yi Li et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Nano-imaging of trace metals by synchrotron X-ray fluorescence into dopaminergic single cells and neurite-like processes

(2008) Asuncion Carmona et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

A potential pathogenetic role of iron in Alzheimer's disease

(2008) Laura Silvestri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Study of Cu chemical state inside single neurons from Parkinson's disease and control substantia nigra using the micro-XANES technique

(2008) Joanna Chwiej et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Quantitative elemental bio-imaging of Mn, Fe, Cu and Zn in 6-hydroxydopamine induced Parkinsonism mouse models

(2008) Dominic Hare et al.   Metallomics

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

(2008) Paul Edison et al.   NEUROBIOLOGY OF DISEASE

Midbrain iron content in early Parkinson disease: A potential biomarker of disease status

(2008) W. R. W. Martin et al.   NEUROLOGY

Challenges in Applying Photoemission Electron Microscopy to Biological Systems

(2008) Dana N. Peles et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-synuclein and its role in metal binding: Relevance to Parkinson's disease

(2007) Josephine A. Wright et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats

(2007) M. Morello et al.   NEUROTOXICOLOGY

Brain iron pathways and their relevance to Parkinson's disease

(2003) D Berg et al.   JOURNAL OF NEUROCHEMISTRY

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

(2003) Craig S. Atwood et al.   JOURNAL OF NEUROCHEMISTRY