Zinc finger proteins as templates for metal ion exchange and ligand reactivity. Chemical and biological consequences

The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation

(2010) Aaron Klug   Annual Review of Biochemistry

Inhibition of HIV-1 Replication by a Bis-Thiadiazolbenzene-1,2-Diamine That Chelates Zinc Ions from Retroviral Nucleocapsid Zinc Fingers

(2010) C. Pannecouque et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Zinc Finger Transcription Factor Zn3-Sp1 Reactions with Cd2+

(2010) Rajendra Kothinti et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Antiretroviral drugs

(2010) Erik De Clercq   CURRENT OPINION IN PHARMACOLOGY

Cysteine Oxidation Enhanced by Iron in Tristetraprolin, A Zinc Finger Peptide

(2010) Seung Jae Lee et al.   INORGANIC CHEMISTRY

Cysteine proteases as targets for metal-based drugs

(2010) Simon P. Fricker   Metallomics

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Zinc Fingers as Biologic Redox Switches?

(2009) Klaus-D. Kröncke et al.   ANTIOXIDANTS & REDOX SIGNALING

Comparison ofcisandtrans-Platinum Mononucleobase Compounds with DNA and Protein Models

(2009) Joseph V. Strukl et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein

(2009) Volodymyr Shvadchak et al.   BIOCHIMIE

Coordination Dynamics of Zinc in Proteins

(2009) Wolfgang Maret et al.   CHEMICAL REVIEWS

Structural Adaptability of Zinc Binding Sites: Different Structures in Partially, Fully, and Heavy-Metal Loaded States

(2009) Uwe Heinz et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Correlation of113Cd NMR and111mCd PAC Spectroscopies Provides a Powerful Approach for the Characterization of the Structure of CdII-Substituted ZnIIProteins

(2009) Olga Iranzo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

(2009) Alberto Bindoli et al.   COORDINATION CHEMISTRY REVIEWS

RING Finger E3 Ubiquitin Ligases: Structure and Drug Discovery

(2009) Christos Chasapis et al.   CURRENT PHARMACEUTICAL DESIGN

Reactions of palladium and gold complexes with zinc-thiolate chelates using electrospray mass spectrometry and X-ray diffraction: molecular identification of [Pd(bme-dach)], [Au(bme-dach]+ and [ZnCl(bme-dach)]2Pd

(2009) Queite A. de Paula et al.   DALTON TRANSACTIONS

PARP inhibitors in cancer therapy: Two modes of attack on the cancer cell widening the clinical applications

(2009) Yvette Drew et al.   DRUG RESISTANCE UPDATES

Towards Antitumor Activetrans-Platinum Compounds

(2009) Sheena M. Aris et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Development of Five-Coordinate Zinc Mono- and Dithiolates as S-Donor Metalloligands: Formation of a Zn−W Coordination Polymer

(2009) Elky Almaraz et al.   INORGANIC CHEMISTRY

Biological Responses to Arsenic Compounds

(2009) Leonidas C. Platanias   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel targets for anti-retroviral therapy

(2009) Sanjay Bhattacharya et al.   JOURNAL OF INFECTION

Zinc finger proteins as templates for metal ion exchange: Substitution effects on the C-finger of HIV nucleocapsid NCp7 using M(chelate) species (M=Pt, Pd, Au)

(2009) Queite A. de Paula et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Twenty-Six Years of Anti-HIV Drug Discovery: Where Do We Stand and Where Do We Go?

(2009) Youcef Mehellou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate

(2009) A. S. Harney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current status of cadmium as an environmental health problem

(2009) Lars Järup et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Historical perspectives on cadmium toxicology

(2009) Gunnar F. Nordberg   TOXICOLOGY AND APPLIED PHARMACOLOGY

Interaction of trivalent antimony with a CCHC zinc finger domain: potential relevance to the mechanism of action of antimonial drugs

(2008) Cynthia Demicheli et al.   CHEMICAL COMMUNICATIONS

Monomethylarsonous Acid Destroys a Tetrathiolate Zinc Finger Much More Efficiently than Inorganic Arsenite: Mechanistic Considerations and Consequences for DNA Repair Inhibition

(2008) Katarzyna Pia̧tek et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Zinc metalloproteins as medicinal targets

(2008) A. I. Anzellotti et al.   CHEMICAL SOCIETY REVIEWS

New Redesigned Zinc-Finger Proteins: Design Strategy and Its Application

(2008) Shigeru Negi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Poly(ADP-ribose)polymerase-1 (PARP-1) in carcinogenesis: potential role of PARP inhibitors in cancer treatment

(2008) Andreína Peralta-Leal et al.   Clinical & Translational Oncology

Metabolism and the Paradoxical Effects of Arsenic: Carcinogenesis and Anticancer

(2008) Xing Cui et al.   CURRENT MEDICINAL CHEMISTRY

DNA repair gets physical: Mapping an XPA-binding site on ERCC1

(2008) Deborah L. Croteau et al.   DNA REPAIR

Arsenic trioxide

(2008) Mark R Litzow   EXPERT OPINION ON PHARMACOTHERAPY

The Alkylation Mechanism of Zinc-Bound Thiolates Depends upon the Zinc Ligands

(2008) Delphine Picot et al.   INORGANIC CHEMISTRY

Effects of Nucleobase Metalation on Frontier Molecular Orbitals: Potential Implications for π-Stacking Interactions with Tryptophan

(2008) Atilio I. Anzellotti et al.   INORGANIC CHEMISTRY

Spectroscopic Evidence for the Formation of Goldfingers

(2008) Matthew A. Franzman et al.   INORGANIC CHEMISTRY

Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide

(2008) Yong Hwan Han et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Physical Basis of Structural and Catalytic Zn-Binding Sites in Proteins

(2008) Yu-ming Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (−)Primer Binding Site During Reverse Transcription

(2008) Sarah Bourbigot et al.   JOURNAL OF MOLECULAR BIOLOGY

Thiolate Bridging and Metal Exchange in Adducts of a Zinc Finger Model and PtIIComplexes: Biomimetic Studies of Protein/Pt/DNA Interactions

(2008) Elky Almaraz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting the Viral Nucleocapsid Protein in Anti-HIV-1 Therapy

(2008) Yves Mely et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif

(2008) A. Arora et al.   RNA

The Expanding Role of Arsenic in Acute Promyelocytic Leukemia

(2008) Martin S. Tallman   SEMINARS IN HEMATOLOGY

New insights into the chemical structure and composition of the pentavalent antimonial drugs, meglumine antimonate and sodium stibogluconate

(2007) Frédéric Frézard et al.   JOURNAL OF INORGANIC BIOCHEMISTRY