Stem-Cell Challenges in the Treatment of Alzheimer's Disease: A Long Way from Bench to Bedside
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Title
Stem-Cell Challenges in the Treatment of Alzheimer's Disease: A Long Way from Bench to Bedside
Authors
Keywords
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Journal
MEDICINAL RESEARCH REVIEWS
Volume 34, Issue 5, Pages 957-978
Publisher
Wiley
Online
2014-02-05
DOI
10.1002/med.21309
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Note: Only part of the references are listed.- Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models
- (2013) Jin Young Shin et al. Autophagy
- To Be Immunogenic, or Not to Be: That’s the iPSC Question
- (2013) Shin Kaneko et al. Cell Stem Cell
- Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells
- (2013) Prajna Guha et al. Cell Stem Cell
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- Intracerebral Transplantation of Adipose-Derived Mesenchymal Stem Cells Alternatively Activates Microglia and Ameliorates Neuropathological Deficits in Alzheimer's Disease Mice
- (2013) Tuo Ma et al. CELL TRANSPLANTATION
- Bone Marrow-Derived Mesenchymal Stem Cells Contribute to the Reduction of Amyloid-β Deposits and the Improvement of Synaptic Transmission in a Mouse Model of Pre-Dementia Alzheimer’s Disease
- (2013) Jae-sung Bae et al. Current Alzheimer Research
- How stem cells speak with host immune cells in inflammatory brain diseases
- (2013) Stefano Pluchino et al. GLIA
- Human adipose tissue-derived mesenchymal stem cells improve cognitive function and physical activity in ageing mice
- (2013) Dongsun Park et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
- (2013) Ryoko Araki et al. NATURE
- Medial ganglionic eminence–like cells derived from human embryonic stem cells correct learning and memory deficits
- (2013) Yan Liu et al. NATURE BIOTECHNOLOGY
- Long-term immunomodulatory effect of amniotic stem cells in an Alzheimer's disease model
- (2013) Kyung-Sul Kim et al. NEUROBIOLOGY OF AGING
- Improvement of cognitive function and physical activity of aging mice by human neural stem cells over-expressing choline acetyltransferase
- (2013) Dongsun Park et al. NEUROBIOLOGY OF AGING
- Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model
- (2013) Hui Yang et al. Stem Cell Research & Therapy
- Regenerative therapy for neuronal diseases with transplantation of somatic stem cells
- (2013) Hiroshi Kanno World Journal of Stem Cells
- The function of BMP4 during neurogenesis in the adult hippocampus in Alzheimer's disease
- (2012) Haiwei Xu et al. AGEING RESEARCH REVIEWS
- Experimental research Enhanced connexin 43 expression following neural stem cell transplantation in a rat model of traumatic brain injury
- (2012) Bo Yu et al. Archives of Medical Science
- Neural stem cells: therapeutic potential for neurodegenerative diseases
- (2012) G. Gincberg et al. BRITISH MEDICAL BULLETIN
- Human Neural Stem Cells Genetically Modified to Express Human Nerve Growth Factor (NGF) Gene Restore Cognition in the Mouse with Ibotenic Acid-Induced Cognitive Dysfunction
- (2012) Hong J. Lee et al. CELL TRANSPLANTATION
- Stem Cell Therapy for Alzheimers Disease
- (2012) Omar M.E. Abdel-Salam CNS & Neurological Disorders-Drug Targets
- Brain Environment and Alzheimer’s Disease Mutations Affect the Survival, Migration and Differentiation of Neural Progenitor Cells
- (2012) Virve Karkkainen et al. Current Alzheimer Research
- Where, when, and in what form does sporadic Alzheimerʼs disease begin?
- (2012) Heiko Braak et al. CURRENT OPINION IN NEUROLOGY
- Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery
- (2012) Jiho Jang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Recent preclinical evidence advancing cell therapy for Alzheimer's disease
- (2012) Cesar V. Borlongan EXPERIMENTAL NEUROLOGY
- Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction
- (2012) Dongsun Park et al. EXPERIMENTAL NEUROLOGY
- Alzheimer's disease in a dish: promises and challenges of human stem cell models
- (2012) J. E. Young et al. HUMAN MOLECULAR GENETICS
- In vitro differentiation of human umbilical cord mesenchymal stem cells (hUCMSCs), derived from Wharton's jelly, into choline acetyltransferase (ChAT)-positive cells
- (2012) Lei Zhang et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer’s disease
- (2012) Lezanne Ooi et al. JOURNAL OF NEURAL TRANSMISSION
- Embryonic stem cell trials for macular degeneration: a preliminary report
- (2012) Steven D Schwartz et al. LANCET
- Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research
- (2012) Takuya Yagi et al. PLoS One
- The Preventive and Therapeutic Effects of Intravenous Human Adipose-Derived Stem Cells in Alzheimer’s Disease Mice
- (2012) Saeromi Kim et al. PLoS One
- A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome
- (2012) Y. Shi et al. Science Translational Medicine
- Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1
- (2012) Debora Giunti et al. STEM CELLS
- Concise Review: Can Stem Cells be Used to Treat or Model Alzheimer's Disease?
- (2012) Wesley W. Chen et al. STEM CELLS
- Soluble CCL5 Derived from Bone Marrow-Derived Mesenchymal Stem Cells and Activated by Amyloid β Ameliorates Alzheimer's Disease in Mice by Recruiting Bone Marrow-Induced Microglia Immune Responses
- (2012) Jong Kil Lee et al. STEM CELLS
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- (2011) Miroslav Pohanka BIOMEDICAL PAPERS-OLOMOUC
- Neuroregeneration in neurodegenerative disorders
- (2011) Ana M Enciu et al. BMC Neurology
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- (2011) Robert H. Andres et al. BRAIN
- In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics
- (2011) Michael A. Bonaguidi et al. CELL
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- (2011) J-Y Kim et al. CELL DEATH AND DIFFERENTIATION
- Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Cognitive Function of Kainic Acid-Induced Learning and Memory Deficit Animals
- (2011) Dongsun Park et al. CELL TRANSPLANTATION
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Risk factors in the development of stem cell therapy
- (2011) Carla A Herberts et al. Journal of Translational Medicine
- Adult hippocampal neurogenesis and its role in Alzheimer's disease
- (2011) Yangling Mu et al. Molecular Neurodegeneration
- Immunogenicity of induced pluripotent stem cells
- (2011) Tongbiao Zhao et al. NATURE
- BDNF-, IGF-1- and GDNF-Secreting Human Neural Progenitor Cells Rescue Amyloid β-Induced Toxicity in Cultured Rat Septal Neurons
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- Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
- (2011) Naoki Yahata et al. PLoS One
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- (2011) Eun-Gyung Cho et al. PLoS One
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- (2011) Christopher J. Bissonnette et al. STEM CELLS
- Teratomas from pluripotent stem cells: A clinical hurdle
- (2010) Chui-Yee Fong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy
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- Hypoxic preconditioning increases gap-junctional graft and host communication
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- (2010) J. Jaderstad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Control of Transplantable Human ESC-Derived Neurons Via Optogenetic Targeting
- (2010) Jason P. Weick et al. STEM CELLS
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- (2010) Albrecht Stroh et al. STEM CELLS
- Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures
- (2009) Mark H. Chin et al. Cell Stem Cell
- Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in Alzheimerian rats
- (2009) Farshad Homayouni Moghadam et al. DIFFERENTIATION
- Soluble CD40 ligand in dementia
- (2009) B. Giunta et al. DRUGS OF THE FUTURE
- A method for rapid derivation and propagation of neural progenitors from human embryonic stem cells
- (2009) Mathilda Zetterström Axell et al. JOURNAL OF NEUROSCIENCE METHODS
- Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
- (2009) M. Blurton-Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Current progress and prospects of induced pluripotent stem cells
- (2009) LingYi Chen et al. Science in China. Series C, Life sciences / Chinese Academy of Sciences
- Genome-Wide Association Studies in Alzheimer Disease
- (2008) Stephen C. Waring et al. ARCHIVES OF NEUROLOGY
- Decreased hippocampal cell proliferation correlates with increased expression of BMP4 in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease
- (2008) Dabing Li et al. HIPPOCAMPUS
- Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged and Alzheimer patients
- (2008) L. Wu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- BDNF improves the effects of neural stem cells on the rat model of Alzheimer's disease with unilateral lesion of fimbria-fornix
- (2008) A.G. Xuan et al. NEUROSCIENCE LETTERS
- Effects of engrafted neural stem cells in Alzheimer's disease rats
- (2008) A.G. Xuan et al. NEUROSCIENCE LETTERS
- Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model
- (2008) Jong Kil Lee et al. NEUROSCIENCE LETTERS
- Embryonic stem cell-derived neural precursor cells improve memory dysfunction in Aβ(1–40) injured rats
- (2008) Jun Tang et al. NEUROSCIENCE RESEARCH
- Peripherally Administered Human Umbilical Cord Blood Cells Reduce Parenchymal and Vascular β-Amyloid Deposits in Alzheimer Mice
- (2008) William V. Nikolic et al. STEM CELLS AND DEVELOPMENT
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