Neuropeptides SP and CGRP Diminish the Moraxella catarrhalis Outer Membrane Vesicle- (OMV-) Triggered Inflammatory Response of Human A549 Epithelial Cells and Neutrophils

Virulence factors of Moraxella catarrhalis outer membrane vesicles are major targets for cross-reactive antibodies and have adapted during evolution

(2018) Daria Augustyniak et al.   Scientific Reports

Exposure to cigarette smoke extract and lipopolysaccharide modifies cytoskeleton organization in bronchial epithelial cells

(2017) Claudia D'Anna et al.   EXPERIMENTAL LUNG RESEARCH

CGRP attenuates hyperoxia-induced oxidative stress-related injury to alveolar epithelial type II cells via the activation of the Sonic hedgehog pathway

(2017) Hong-Xing Dang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Moraxella catarrhalis vaccine to protect against otitis media and exacerbations of COPD: An update on current progress and challenges

(2017) Antonia C. Perez et al.   Human Vaccines & Immunotherapeutics

A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ

(2017) Ji Eun Lim et al.   Scientific Reports

Bactericidal, opsonophagocytic and anti-adhesive effectiveness of cross-reactive antibodies against Moraxella catarrhalis

(2015) Daria Augustyniak et al.   Pathogens and Disease

Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

(2014) Mark D. Turner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroimmunological communication via CGRP promotes the development of a regulatory phenotype in TLR4-stimulated macrophages

(2014) Mariona Baliu-Piqué et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of Substance P on type II alveolar epithelial cells exposed to hyperoxia and its regulation of the Sonic hedgehog signaling pathway

(2014) CONG LIU et al.   Molecular Medicine Reports

Oxidative stress and free radicals in COPD – implications and relevance for treatment

(2014) Wolfgang Domej et al.   International Journal of Chronic Obstructive Pulmonary Disease

Direct and Indirect Antimicrobial Activities of Neuropeptides and their Therapeutic Potential

(2013) Daria Augustyniak et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Antiinflammatory Activities of CGRP Modulating Innate Immune Responses in Health and Disease

(2013) Bernhard Holzmann   CURRENT PROTEIN & PEPTIDE SCIENCE

Innate immune properties of selected human neuropeptides against Moraxella catarrhalis and nontypeable Haemophilus influenzae

(2012) Daria Augustyniak et al.   BMC IMMUNOLOGY

ß-Defensins: Multifunctional Modulators of Infection, Inflammation and More?

(2012) Fiona Semple et al.   Journal of Innate Immunity

Beta Defensin-2 Is Reduced in Central but Not in Distal Airways of Smoker COPD Patients

(2012) Elisabetta Pace et al.   PLoS One

Modulation of immune responses by the neuropeptide CGRP

(2011) Bernhard Holzmann   AMINO ACIDS

Calcitonin gene-related peptide– and vascular endothelial growth factor–positive inflammatory cells in late-phase allergic skin reactions in atopic subjects

(2011) A. Barry Kay   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Acinetobacter baumannii Secretes Cytotoxic Outer Membrane Protein A via Outer Membrane Vesicles

(2011) Jong Sook Jin et al.   PLoS One

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells

(2010) Viveka Schaar et al.   CELLULAR MICROBIOLOGY

Neuropeptides: keeping the balance between pathogen immunity and immune tolerance

(2010) Elena Gonzalez-Rey et al.   CURRENT OPINION IN PHARMACOLOGY

TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure

(2010) Elisabetta Pace et al.   HUMAN IMMUNOLOGY

Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells

(2010) Bernhard B. Singer et al.   PLoS One

Moraxella catarrhalisacquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease

(2009) Ganapathi I Parameswaran et al.   BMC INFECTIOUS DISEASES

The Neuropeptide Calcitonin Gene-related Peptide Causes Repression of Tumor Necrosis Factor-α Transcription and Suppression of ATF-2 Promoter Recruitment in Toll-like Receptor-stimulated Dendritic Cells

(2009) Felicitas Altmayr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Neutrophils Kill Streptococcus pneumoniae via Serine Proteases

(2009) A. J. Standish et al.   JOURNAL OF IMMUNOLOGY

Differential Modulation of TNF-α–Induced Apoptosis by Neisseria meningitidis

(2009) Ala-Eddine Deghmane et al.   PLoS Pathogens

Evaluation of the effect of human  -defensins on neutrophil apoptosis

(2008) I. Nagaoka et al.   INTERNATIONAL IMMUNOLOGY

CEACAM1 inhibits Toll-like receptor 2–triggered antibacterial responses of human pulmonary epithelial cells

(2008) Hortense Slevogt et al.   NATURE IMMUNOLOGY

Outer membrane protein UspA1 and lipooligosaccharide are involved in invasion of human epithelial cells by Moraxella catarrhalis

(2007) Violeta Spaniol et al.   MICROBES AND INFECTION