Bacterial Pathogens Commandeer Rab GTPases to Establish Intracellular Niches

Rab GTPases and microtubule motors

(2012) Conor P. Horgan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mycobacterium avium-triggered diseases: pathogenomics

(2012) Dmitriy Ignatov et al.   CELLULAR MICROBIOLOGY

Adenylating Enzymes in Mycobacterium tuberculosis as Drug Targets

(2012) Benjamin P. Duckworth et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Reversible phosphocholination of Rab proteins byLegionella pneumophilaeffector proteins

(2012) Philip R Goody et al.   EMBO JOURNAL

Role of Rab family GTPases and their effectors in melanosomal logistics

(2012) N. Ohbayashi et al.   JOURNAL OF BIOCHEMISTRY

Structure ofSalmonellaEffector Protein SopB N-terminal Domain in Complex with Host Rho GTPase Cdc42

(2012) Brianne J. Burkinshaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ASalmonella typhimurium-translocated Glycerophospholipid:Cholesterol Acyltransferase Promotes Virulence by Binding to the RhoA Protein Switch Regions

(2012) Doris L. LaRock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multistep activation of the Helicobacter pylori effector CagA

(2012) Anne Müller   JOURNAL OF CLINICAL INVESTIGATION

Mycobacterium tuberculosis-Specific Phagosome Proteome and Underlying Signaling Pathways

(2012) Ying He et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative Proteomics Reveals That Only a Subset of the Endoplasmic Reticulum Contributes to the Phagosome

(2012) François-Xavier Campbell-Valois et al.   MOLECULAR & CELLULAR PROTEOMICS

The Bimodal Lifestyle of Intracellular Salmonella in Epithelial Cells: Replication in the Cytosol Obscures Defects in Vacuolar Replication

(2012) Preeti Malik-Kale et al.   PLoS One

Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor

(2012) L. K. Oesterlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secretive Bacterial Pathogens and the Secretory Pathway

(2012) Hubert Hilbi et al.   TRAFFIC

Rabs and other small GTPases in ciliary transport

(2011) Yi Shan Lim et al.   BIOLOGY OF THE CELL

Multi-genome identification and characterization of chlamydiae-specific type III secretion substrates: the Inc proteins

(2011) Pierre Dehoux et al.   BMC GENOMICS

Salmonella effectors: important players modulating host cell function during infection

(2011) Terence A. Agbor et al.   CELLULAR MICROBIOLOGY

Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors

(2011) Jianning Ge et al.   CELLULAR MICROBIOLOGY

Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer

(2011) Natalia A. Kaniuk et al.   CELLULAR MICROBIOLOGY

Disruption of Wnt Planar Cell Polarity Signaling by Aberrant Accumulation of the MetAP-2 Substrate Rab37

(2011) Thomas B. Sundberg et al.   CHEMISTRY & BIOLOGY

Rab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities

(2011) JO Agola et al.   CLINICAL GENETICS

Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1

(2011) Cláudia Rosa-Ferreira et al.   DEVELOPMENTAL CELL

Dynamic modification of microtubule-dependent transport by effector proteins of intracellular Salmonella enterica

(2011) Roopa Rajashekar et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Identification and modelling of a PPM protein phosphatase fold in theLegionella pneumophiladeAMPylase SidD

(2011) Daniel J. Rigden   FEBS LETTERS

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

Pathogens and polymers: Microbe–host interactions illuminate the cytoskeleton

(2011) Cat M. Haglund et al.   JOURNAL OF CELL BIOLOGY

Recent advances in Chlamydia subversion of host cytoskeletal and membrane trafficking pathways

(2011) Marci A. Scidmore   MICROBES AND INFECTION

The macro domain protein family: Structure, functions, and their potential therapeutic implications

(2011) Weidong Han et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Protein LidA from Legionella is a Rab GTPase supereffector

(2011) S. Schoebel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella

(2011) S. Spano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Rab GTPases Regulating Phagosome Maturation Are Differentially Recruited to Mycobacterial Phagosomes

(2011) Shintaro Seto et al.   TRAFFIC

Salmonella-induced tubular networks

(2011) Nina Schroeder et al.   TRENDS IN MICROBIOLOGY

Species-Specific Interactions of Src Family Tyrosine Kinases Regulate Chlamydia Intracellular Growth and Trafficking

(2011) C. A. Elwell et al.   mBio

Salmonella – At Home in the Host Cell

(2011) Preeti Malik-Kale et al.   Frontiers in Microbiology

Subversion of Mucosal Barrier Polarity by Pseudomonas Aeruginosa

(2011) Joanne Engel et al.   Frontiers in Microbiology

Type IVB Secretion Systems of Legionella and Other Gram-Negative Bacteria

(2011) Hiroki Nagai et al.   Frontiers in Microbiology

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella

(2011) Hubert Hilbi et al.   Frontiers in Microbiology

Bacterial Contact-Dependent Delivery Systems

(2010) Christopher S. Hayes et al.   Annual Review of Genetics

Rab11-FIP3 binds dynein light intermediate chain 2 and its overexpression fragments the Golgi complex

(2010) Conor P. Horgan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression, Purification, and Characterization of a Recombinant Neutral Ceramidase fromMycobacterium tuberculosis

(2010) Nozomu OKINO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Specific chlamydial inclusion membrane proteins associate with active Src family kinases in microdomains that interact with the host microtubule network

(2010) Jeffrey Mital et al.   CELLULAR MICROBIOLOGY

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

Bacterial Invasion: Entry through the Exocyst Door

(2010) Virginie Braun et al.   CURRENT BIOLOGY

Protein export systems ofMycobacterium tuberculosis: novel targets for drug development?

(2010) Meghan E Feltcher et al.   Future Microbiology

Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors

(2010) R. Bulgin et al.   INFECTION AND IMMUNITY

The ADP-Ribosylation Domain of Pseudomonas aeruginosa ExoS Is Required for Membrane Bleb Niche Formation and Bacterial Survival within Epithelial Cells

(2010) A. A. Angus et al.   INFECTION AND IMMUNITY

Rab32 Modulates Apoptosis Onset and Mitochondria-associated Membrane (MAM) Properties

(2010) Michael Bui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential recruitment of CD63 and Rab7-interacting-lysosomal-protein to phagosomes containingMycobacterium tuberculosisin macrophages

(2010) Shintaro Seto et al.   MICROBIOLOGY AND IMMUNOLOGY

Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia

(2010) Leigh A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of phagosomal proteomes: From latex-bead to bacterial phagosomes

(2010) Qingbo Li et al.   PROTEOMICS

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin-1-Dependent Vacuolar Membrane Exchanges

(2010) Audrey Dumont et al.   TRAFFIC

The Virulence Protein SopD2 Regulates Membrane Dynamics of Salmonella-Containing Vacuoles

(2010) Nina Schroeder et al.   PLoS Pathogens

Dissection of Rab7 localization on Mycobacterium tuberculosis phagosome

(2009) Shintaro Seto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SCAMP3 is a component of theSalmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking

(2009) Luís Jaime Mota et al.   CELLULAR MICROBIOLOGY

The Phagosomal Proteome in Interferon-γ-Activated Macrophages

(2009) Matthias Trost et al.   IMMUNITY

Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium

(2009) Olga Shevchuk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

Rabex-5 Is a Rab22 Effector and Mediates a Rab22-Rab5 Signaling Cascade in Endocytosis

(2009) Huaiping Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

RabGDI Displacement by DrrA from Legionella Is a Consequence of Its Guanine Nucleotide Exchange Activity

(2009) Stefan Schoebel et al.   MOLECULAR CELL

Pathogen trafficking pathways and host phosphoinositide metabolism

(2009) Stefan S. Weber et al.   MOLECULAR MICROBIOLOGY

Modulation of membrane traffic between endoplasmic reticulum, ERGIC and Golgi to generate compartments for the replication of bacteria and viruses

(2009) Roberto Pierini et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Proteome Analysis of Legionella Vacuoles Purified by Magnetic Immunoseparation Reveals Secretory and Endosomal GTPases

(2009) Simon Urwyler et al.   TRAFFIC

Rab10 Regulates Phagosome Maturation and Its Overexpression RescuesMycobacterium-Containing Phagosomes Maturation

(2009) Carla M. P. Cardoso et al.   TRAFFIC

Rab6 and Rab11 Regulate Chlamydia trachomatis Development and Golgin-84-Dependent Golgi Fragmentation

(2009) Anette Rejman Lipinski et al.   PLoS Pathogens

Rab GTPases and their roles in brain neurons and glia

(2008) Ee Ling Ng et al.   BRAIN RESEARCH REVIEWS

v-Src and c-Src, nonpalmitoylated Src-family kinases, induce perinuclear accumulation of lysosomes through Rab7 in a kinase activity-independent manner

(2008) Kousuke Kasahara et al.   CANCER LETTERS

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

Contributions of proteomics to understanding phagosome maturation

(2008) Lindsay D. Rogers et al.   CELLULAR MICROBIOLOGY

Large-scale identification ofLegionella pneumophilaDot/Icm substrates that modulate host cell vesicle trafficking pathways

(2008) Matthew Heidtman et al.   CELLULAR MICROBIOLOGY

CagA ofHelicobacter pylorialters the expression and cellular distribution of host proteins involved in cell signaling

(2008) Zaher Zeaiter et al.   FEMS MICROBIOLOGY LETTERS

Co-evolution and exploitation of host cell signaling pathways by bacterial pathogens

(2008) Stephanie R. Shames et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

Rab18 and Rab43 have key roles in ER-Golgi trafficking

(2008) S. Y. Dejgaard et al.   JOURNAL OF CELL SCIENCE

The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

(2008) E. Schonteich et al.   JOURNAL OF CELL SCIENCE

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

The Salmonella virulence protein SifA is a G protein antagonist

(2008) L. K. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ankyrin Repeat Proteins Comprise a Diverse Family of Bacterial Type IV Effectors

(2008) X. Pan et al.   SCIENCE

Characterization of a Listeria monocytogenes Protein Interfering with Rab5a

(2008) Carmen Alvarez-Dominguez et al.   TRAFFIC

Dynamic Remodeling of the Endosomal System During Formation ofSalmonella-Induced Filaments by IntracellularSalmonella enterica

(2008) Roopa Rajashekar et al.   TRAFFIC

Endosomal trafficking of Src tyrosine kinase

(2008) Emma Sandilands et al.   TRENDS IN CELL BIOLOGY

SNARE Protein Mimicry by an Intracellular Bacterium

(2008) Cédric Delevoye et al.   PLoS Pathogens