Article
Nanoscience & Nanotechnology
Lisa M. Stabryla, Kathryn A. Johnston, Nathan A. Diemler, Vaughn S. Cooper, Jill E. Millstone, Sarah-Jane Haig, Leanne M. Gilbertson
Summary: Bacterial motility can be a significant predictor of AgNP resistance, guiding the development of nanoenabled antimicrobials. The study of bacterial resistance to AgNPs is still in its early stages, with limited understanding of the underlying mechanisms. The resistance to subinhibitory concentrations of AgNPs in Escherichia coli K-12 MG1655 strain was found to be associated with a cusS mutation, potentially enhancing silver ion efflux and suggesting a role for flagellum-based motility in the resistance mechanism.
NATURE NANOTECHNOLOGY
(2021)
Article
Ecology
Alise R. Muok, Dennis Claessen, Ariane Briegel
Summary: Streptomyces spores can utilize the motility machinery of other soil bacteria to be transported to plant tissues by interacting with the flagella of both gram-positive and gram-negative bacteria. This highlights the capability of nonmotile bacteria to use the motility machinery of other microbes to complete necessary stages of their lifecycle.
Article
Environmental Sciences
Y. Perez-Jimenez, I De-la-Rosa-Gomez, D. Alcantara, M. T. Olguin
Summary: The effect of chloride ions on the antimicrobial activity of silver composites was investigated. The adsorption of chloride ions by a composite formed by chitosan and natural zeolite with supported silver nanoparticles obtained by gamma irradiation was also considered. The presence of chloride ions in the solution was found to increase the cell decay time, while without chloride ions, the microbial mortality rate reached 100% within two hours.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Elham Avirdi, Hugues Kamdem Paumo, Boniface Pone Kamdem, Madhur Babu Singh, Kamlesh Kumari, Lebogang Katata-Seru, Indra Bahadur
Summary: This study reports the experimental research of citrate-mediated reduction of silver ions in three different ionic liquids, resulting in Ag-ILs nanoparticles with significant antibacterial activity. The nanoparticles were characterized using various analytical techniques and computational calculations.
Article
Multidisciplinary Sciences
Junior Bernardo Molina-Hernandez, Antonio Aceto, Tonino Bucciarelli, Domenico Paludi, Luca Valbonetti, Katiuscia Zilli, Luca Scotti, Clemencia Chaves-Lopez
Summary: This study demonstrates that hand-made synthesized silver ultra nanoclusters are highly effective bactericides and anti-biofilm agents, eradicating biofilms at low concentrations. The researchers suggest that disrupting the chemical constitution of crosslinks may be a key mechanism in the antibacterial effects of the nanoparticles.
SCIENTIFIC REPORTS
(2021)
Article
Pharmacology & Pharmacy
Aiman Batool, Mercy Bore, Jingwen Wu, Chaoyu Li, Hongjuan Zeng
Summary: The combination of silver nanoparticles and cefazolin can enhance the antibacterial effectiveness of cefazolin, exhibiting strong antibacterial activity against Escherichia coli and Staphylococcus aureus.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Eman Hassanen, Eman A. Morsy, Ahmed M. Hussien, Khaled Y. Farroh, Merhan E. Ali
Summary: The study investigated the bactericidal effect of copper, silver, and chitosan nanoparticles against E. coli infection in broilers, and found that Ch-Ag NPs not only had the best antibacterial effects, but also acted as a growth promoter in broilers without leaving any residues in edible organs.
BIOSCIENCE REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Noura El-Kattan, Ahmed N. Emam, Ahmed S. Mansour, Mostafa A. Ibrahim, Ashraf B. Abd El-Razik, Kamilia A. M. Allam, Nadia Youssef Riad, Samir A. Ibrahim
Summary: According to WHO warnings, the antibiotic resistance crisis is a severe health issue in the 21st century. This study used green-synthesized silver and zinc oxide nanoparticles to combat multi-drug resistant bacteria, showing promising antimicrobial activity.
Article
Biochemistry & Molecular Biology
Zhilei Li, Lang He, Xia Wang, Qingwen Huo, Guosong Zheng, Dekun Kong, Yinhua Lu, Haiyang Xia, Guoqing Niu
Summary: Sideromycins are a unique subset of siderophores that combine a siderophore and an antimicrobial agent. This study deciphered the biosynthetic pathway of the ferrichrome-type siderophore in Streptomyces sp. ATCC 700974 and identified the involved genes. The findings provide important insights into the synthesis of albomycin and the role of multiple siderophores in Streptomyces sp. ATCC 700974.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Padikkamannil Abishad, Jess Vergis, Varsha Unni, Vemula Prasastha Ram, Pollumahanti Niveditha, Jyothsana Yasur, Sanis Juliet, Lijo John, Kullaiya Byrappa, Prejit Nambiar, Nitin Vasantrao Kurkure, Sukhadeo Baliram Barbuddhe, Deepak Bhiwa Rawool
Summary: This study successfully synthesized green silver nanoparticles using probiotic strain Lactobacillus acidophilus, which demonstrated antibacterial and antibiofilm activity against multi-drug-resistant enteroaggregative Escherichia coli (MDR-EAEC) strains. Additionally, the green synthesized AgNPs showed antioxidant properties.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Article
Biotechnology & Applied Microbiology
Soha Elshaer, Mona I. Shaaban
Summary: This study evaluated the effects of biologically synthesized silver and copper nanoparticles on bacterial attachment and viability of dormant cells within the biofilm matrix. The nanoparticles significantly reduced bacterial attachment and viable cells in the biofilm matrix, and eradicated mature biofilms formed by various Gram-negative pathogens. Furthermore, they also reduced the expression of biofilm-associated genes. Therefore, these nanoparticles could be used as adjuvant therapy in the eradication of antibiotic resistance and biofilm matrix associated with Gram-negative bacterial infection.
Article
Chemistry, Applied
Li Wang, Govindasami Periyasami, Ali Aldalbahi, Vincenzo Fogliano
Summary: The study compared the effects of chitosan and PVA-based BSNPs films on the growth of Pseudomonas fluorescens, showing that PVA-based BSNPs film exhibited stronger antimicrobial effects. This is attributed to the higher amount of silver ions released from the PVA film into the hydrogel.
Article
Biochemistry & Molecular Biology
Nishal M. Egodawaththa, Amy L. Knight, Jingxuan Ma, D. Andrew Knight, Eric Guisbert, Nasri Nesnas
Summary: Silver nanoparticles conjugated with organic ligands have been successfully synthesized and demonstrated significant antimicrobial activity and antibacterial capabilities against E. coli. The synthesis of functionalized silver nanoparticles is critical for the further development of silver-nanoconjugated antibacterial agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Acoustics
Shen Yang, Zijin Yuan, Jude Juventus Aweya, Shiying Huang, Shanggui Deng, Linfan Shi, Mingjing Zheng, Yueling Zhang, Guangming Liu
Summary: This study found that the in silico predicted antimicrobial peptide TGH2 combined with low-intensity ultrasound significantly reduced the minimum inhibitory concentration of Escherichia coli and enhanced bactericidal effect, as shown by transmission electron microscopy and circular dichroism for structural analysis.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Monica Paesa, Fernando Almazan, Cristina Yus, Victor Sebastian, Manuel Arruebo, Luis M. Gandia, Santiago Reinoso, Ismael Pellejero, Gracia Mendoza
Summary: This study investigates the antimicrobial performance of polyoxometalate-stabilized gold nanoparticles against Escherichia coli and Staphylococcus aureus, finding that one particular composite exhibits excellent bactericidal efficiency without harming mammalian cells.
Article
Biochemistry & Molecular Biology
Deene Manikprabhu, K. Lingappa
BIOINORGANIC CHEMISTRY AND APPLICATIONS
(2013)
Article
Microbiology
S. Amena, N. Vishalakshi, M. Prabhakar, A. Dayanand, K. Lingappa
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2010)
Article
Biotechnology & Applied Microbiology
Deene Manik Prabhu, Syed Raziuddin Quadri, Juan Cheng, Lan Liu, Wei Chen, Ying Yang, Wael N. Hozzein, Kattimani Lingappa, Wen-Jun Li
JOURNAL OF ANTIBIOTICS
(2015)
Article
Metallurgy & Metallurgical Engineering
Deene Manikprabhu, K. Lingappa
ACTA METALLURGICA SINICA-ENGLISH LETTERS
(2013)
Article
Biology
Deene Manikprabhu, K. Lingappa
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2013)
Article
Biotechnology & Applied Microbiology
Ananda Sindhe, K. Lingappa
Summary: This study isolated and screened microorganisms from different samples in the Kalyan-Karnataka region, India for their naringinase production. Among the isolated strains, 42 were fungi and 8 were bacteria, with KLA-80 showing the highest naringinase activity (559 U/ml) and identified as Aspergillus flavus through BLAST analysis.
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Sarfaraz Ahmed, Prabhurajeshwar, Lingappa Kattimani
Summary: Lactose is the main sugar in milk and serves as the main energy source for infants. Lactose intolerance can cause symptoms like diarrhea and abdominal cramping, and an estimated 30% of the population in developing countries may suffer from this condition. Lactic acid bacteria may aid in digesting lactose in fermented dairy products, potentially benefiting those with lactose intolerance.
RESEARCH JOURNAL OF BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
K. G. Siddalingeshwara, K. Lingappa, T. Vishwanatha, T. Pramod
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2014)
Article
Biotechnology & Applied Microbiology
M. Prabhakar, K. Lingappa
RESEARCH JOURNAL OF BIOTECHNOLOGY
(2011)
Article
Biotechnology & Applied Microbiology
S. Amena, K. Lingappa, N. Vishalakshi, M. Prabhakar, A. Dayanand
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2010)
Article
Biotechnology & Applied Microbiology
N. Vishalakshi, K. Lingappa, S. Amena, M. Prabhakar, A. Dayanand
INDIAN JOURNAL OF BIOTECHNOLOGY
(2009)
Article
Engineering, Multidisciplinary
K. Lingappa, T. Pramod, Syed Imtiaz Ali
JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH
(2007)
Article
Biotechnology & Applied Microbiology
A. Shivalee, K. Lingappa, Divatar Mahesh
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY
(2018)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)