4.6 Article

Surface modification of poly(L-lactide) and polycaprolactone bioresorbable polymers using RF plasma discharge with sputter deposition of a hydroxyapatite target

Journal

MATERIALS LETTERS
Volume 132, Issue -, Pages 281-284

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2014.06.115

Keywords

Polymers; Biomaterials; Magnetron sputter deposition; Calcium-phosphate

Funding

  1. Russian Foundation for Basic Research [13-08-98052, 13-08-90743]
  2. Federal Target Program [14.577.21.0036]
  3. Griffith

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Surface modification of poly(L lactide) (L-PLA) and polycaprolactone (PCL) bioresorbable polymers by radio-frequency thermal glow discharge plasma is reported. Improved biocompatibility of L-PLA and PCL materials was obtained by employing hydroxyapatite target sputtering in Ar+ plasma as evidenced by the change of L-PLA and PCL properties from highly hydrophobic to hydrophilic, with absolute wettability obtained for both materials, and enhanced cell line EA-hy 926 attachment to modified surfaces. Surface roughness and surface free energy were found to increase significantly for both polymers under prolonged plasma exposure and, a longer chain aliphatic PCL were found to display a marginally better post plasma-treated biocompatibility compared to L-PLA. (C) 2014 Elsevier B.V. All rights reserved.

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