Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects

Nutritional Biomarkers in Alzheimer's Disease: The Association between Carotenoids, n-3 Fatty Acids, and Dementia Severity

(2017) Wei Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

de novo computational enzyme design

(2014) Alexandre Zanghellini   CURRENT OPINION IN BIOTECHNOLOGY

The role of reorganization energy in rational enzyme design

(2014) Monika Fuxreiter et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Computational tools for designing and engineering enzymes

(2014) Jiri Damborsky et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The P450-type carotene hydroxylase PuCHY1 fromPorphyrasuggests the evolution of carotenoid metabolism in red algae

(2014) Li-En Yang et al.   Journal of Integrative Plant Biology

New and Rare Carotenoids Isolated from Marine Bacteria and Their Antioxidant Activities

(2014) Kazutoshi Shindo et al.   Marine Drugs

Effects of abiotic stressors on lutein production in the green microalga Dunaliella salina

(2014) Weiqi Fu et al.   Microbial Cell Factories

A High-Throughput Colorimetric Screening Assay for Terpene Synthase Activity Based on Substrate Consumption

(2014) Maiko Furubayashi et al.   PLoS One

Reconstruction of the Carotenoid Biosynthetic Pathway of Cronobacter sakazakii BAA894 in Escherichia coli

(2014) Wei Zhang et al.   PLoS One

Screening Factors Influencing the Production of Astaxanthin from Freshwater and Marine Microalgae

(2013) Elda Nurafnie Binti Ibnu Rasid et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Production and glucosylation of C50 and C40 carotenoids by metabolically engineered Corynebacterium glutamicum

(2013) Sabine A. E. Heider et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lycopene production in recombinant strains of Escherichia coli is improved by knockout of the central carbon metabolism gene coding for glucose-6-phosphate dehydrogenase

(2013) Yan Zhou et al.   BIOTECHNOLOGY LETTERS

Chromosomal evolution of Escherichia coli for the efficient production of lycopene

(2013) Yun-Yan Chen et al.   BMC BIOTECHNOLOGY

Evolutionary origins, molecular cloning and expression of carotenoid hydroxylases in eukaryotic photosynthetic algae

(2013) Hongli Cui et al.   BMC GENOMICS

Biosynthetic Pathway and Health Benefits of Fucoxanthin, an Algae-Specific Xanthophyll in Brown Seaweeds

(2013) Koji Mikami et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CAROTENOID CLEAVAGE DIOXYGENASE 7 modulates plant growth, reproduction, senescence, and determinate nodulation in the model legume Lotus japonicus

(2013) Junwei Liu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Engineering central metabolic modules of Escherichia coli for improving β-carotene production

(2013) Jing Zhao et al.   METABOLIC ENGINEERING

Improving carotenoids production in yeast via adaptive laboratory evolution

(2013) Luis H. Reyes et al.   METABOLIC ENGINEERING

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Combining Genotype Improvement and Statistical Media Optimization for Isoprenoid Production in E. coli

(2013) Congqiang Zhang et al.   PLoS One

Randomized BioBrick Assembly: A Novel DNA Assembly Method for Randomizing and Optimizing Genetic Circuits and Metabolic Pathways

(2013) Sean C. Sleight et al.   ACS Synthetic Biology

High-Level Production of the Industrial Product Lycopene by the Photosynthetic Bacterium Rhodospirillum rubrum

(2012) Guo-Shu Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enhancement of carotenoid biosynthesis in the green microalga Dunaliella salina with light-emitting diodes and adaptive laboratory evolution

(2012) Weiqi Fu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of bulk chemicals via novel metabolic pathways in microorganisms

(2012) Jae Ho Shin et al.   BIOTECHNOLOGY ADVANCES

Pathway engineering strategies for production of beneficial carotenoids in microbial hosts

(2012) Victor M. Ye et al.   BIOTECHNOLOGY LETTERS

Scavenging Capacity of Marine Carotenoids against Reactive Oxygen and Nitrogen Species in a Membrane-Mimicking System

(2012) Eliseu Rodrigues et al.   Marine Drugs

The future of metabolic engineering and synthetic biology: Towards a systematic practice

(2012) Vikramaditya G. Yadav et al.   METABOLIC ENGINEERING

Carotenoid-based phenotypic screen of the yeast deletion collection reveals new genes with roles in isoprenoid production

(2012) Bilge Özaydın et al.   METABOLIC ENGINEERING

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

RNA processing enables predictable programming of gene expression

(2012) Lei Qi et al.   NATURE BIOTECHNOLOGY

Modular control of multiple pathways using engineered orthogonal T7 polymerases

(2012) Karsten Temme et al.   NUCLEIC ACIDS RESEARCH

On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase

(2012) Patrick Schaub et al.   PLoS One

Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli

(2011) Yeong-Su Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Optimized compatible set of BioBrick™ vectors for metabolic pathway engineering

(2011) Jacob E. Vick et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Pathway engineering for functional isoprenoids

(2011) Norihiko Misawa   CURRENT OPINION IN BIOTECHNOLOGY

Goldacre Review: Carotenoids in nature: insights from plants and beyond

(2011) Christopher I. Cazzonelli   FUNCTIONAL PLANT BIOLOGY

The allenic carotenoid fucoxanthin, a novel marine nutraceutical from brown seaweeds

(2011) Kazuo Miyashita et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Carotenoid β-Ring Hydroxylase and Ketolase from Marine Bacteria—Promiscuous Enzymes for Synthesizing Functional Xanthophylls

(2011) Norihiko Misawa   Marine Drugs

Carotenoids in Algae: Distributions, Biosyntheses and Functions

(2011) Shinichi Takaichi   Marine Drugs

Microalgae as Sources of Carotenoids

(2011) Ana Catarina Guedes et al.   Marine Drugs

Marine Carotenoids: Biological Functions and Commercial Applications

(2011) Carlos Vílchez et al.   Marine Drugs

Carotenoids in Marine Animals

(2011) Takashi Maoka   Marine Drugs

Reiterative Recombination for the in vivo assembly of libraries of multigene pathways

(2011) L. M. Wingler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial production of farnesol (FOH): Current states and beyond

(2011) Chonglong Wang et al.   PROCESS BIOCHEMISTRY

In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production

(2010) H. S. Choi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of zeaxanthin in recombinant Pseudomonas putida

(2010) Holger Beuttler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Xanthophyllomyces dendrorhous for the industrial production of astaxanthin

(2010) Marta Rodríguez-Sáiz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biotechnological production of lutein and its applications

(2010) José M. Fernández-Sevilla et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enzymes of the mevalonate pathway of isoprenoid biosynthesis

(2010) Henry M. Miziorko   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biosynthetic Pathway for  -Cyclic Sarcinaxanthin in Micrococcus luteus: Heterologous Expression and Evidence for Diverse and Multiple Catalytic Functions of C50 Carotenoid Cyclases

(2010) R. Netzer et al.   JOURNAL OF BACTERIOLOGY

Enhanced Productivity of a Lutein-Enriched Novel Acidophile Microalga Grown on Urea

(2010) Carlos Casal et al.   Marine Drugs

Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides

(2010) Joseph R Warner et al.   NATURE BIOTECHNOLOGY

Carotenoid biosynthesis in diatoms

(2010) Martine Bertrand   PHOTOSYNTHESIS RESEARCH

Anti-angiogenic effect of siphonaxanthin from green alga, Codium fragile

(2010) Ponesakki Ganesan et al.   PHYTOMEDICINE

Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control

(2010) E. Leonard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Novel approaches and achievements in biosynthesis of functional isoprenoids in Escherichia coli

(2009) Hisashi Harada et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Carotenoid production in Bacillus subtilis achieved by metabolic engineering

(2009) Kazuyuki Yoshida et al.   BIOTECHNOLOGY LETTERS

The Biosynthetic Pathway for Myxol-2' Fucoside (Myxoxanthophyll) in the Cyanobacterium Synechococcus sp. Strain PCC 7002

(2009) J. E. Graham et al.   JOURNAL OF BACTERIOLOGY

Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli

(2009) Sang-Hwal Yoon et al.   JOURNAL OF BIOTECHNOLOGY

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Metabolic engineering without plasmids

(2009) Aashiq H Kachroo et al.   NATURE BIOTECHNOLOGY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Uncovering the gene knockout landscape for improved lycopene production in E. coli

(2008) Hal Alper et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biomass and lutein productivity of Scenedesmus almeriensis: influence of irradiance, dilution rate and temperature

(2008) J. F. Sánchez et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evolution of carotene desaturation: The complication of a simple pathway

(2008) Gerhard Sandmann   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Replicon-free and markerless methods for genomic insertion of DNAs in phage attachment sites and controlled expression of chromosomal genes inEscherichia coli

(2008) Chung-Jen Chiang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution

(2008) Julian N Rosenberg et al.   CURRENT OPINION IN BIOTECHNOLOGY

New C37Skeletal Carotenoid from the Clam, Paphia amabillis

(2008) Takashi Maoka et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Isorenieratene Biosynthesis in Green Sulfur Bacteria Requires the Cooperative Actions of Two Carotenoid Cyclases

(2008) J. A. Maresca et al.   JOURNAL OF BACTERIOLOGY

Biochemical and Structural Insights into Bacterial Organelle Form and Biogenesis

(2008) Joshua B. Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary Origins and Functions of the Carotenoid Biosynthetic Pathway in Marine Diatoms

(2008) Sacha Coesel et al.   PLoS One

A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence

(2008) C.-I Liu et al.   SCIENCE

Exploring and exploiting carotenoid accumulation in Dunaliella salina for cell-factory applications

(2008) Packo P. Lamers et al.   TRENDS IN BIOTECHNOLOGY

Increased β-Carotene Production in Recombinant Escherichia coli Harboring an Engineered Isoprenoid Precursor Pathway with Mevalonate Addition

(2007) Sang-Hwal Yoon et al.   BIOTECHNOLOGY PROGRESS