13-Acetoxysarcocrassolide Induces Apoptosis on Human Gastric Carcinoma Cells Through Mitochondria-Related Apoptotic Pathways: p38/JNK Activation and PI3K/AKT Suppression

NVP-BEZ235, a dual PI3K/mTOR inhibitor, induces cell death through alternate routes in prostate cancer cells depending on the PTEN genotype

(2014) Seung-Woo Hong et al.   APOPTOSIS

Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells

(2014) MIN LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Management ofHelicobacter pyloriinfection after gastric surgery

(2014) Yang-Sheng Lin   WORLD JOURNAL OF GASTROENTEROLOGY

Doxorubicin Caused Apoptosis of Mesenchymal Stem Cells via p38, JNK and p53 Pathway

(2013) Fan Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Diverse Mechanisms of AKT Pathway Activation in Human Malignancy

(2013) Mitchell Cheung et al.   CURRENT CANCER DRUG TARGETS

Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells

(2013) Haitao Shen et al.   FOOD AND CHEMICAL TOXICOLOGY

Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway

(2013) Yi-Jen Chen et al.   MOLECULES

Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK

(2013) HE-QI BU et al.   ONCOLOGY REPORTS

Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways

(2013) Chien-Chih Chiu et al.   PLoS One

Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway

(2013) C Lv et al.   Cell Death & Disease

Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells

(2012) Tzu-Rong Su et al.   ELECTROPHORESIS

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

(2012) Luigi Leanza et al.   EMBO Molecular Medicine

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Gastric Cancer: Basic Aspects

(2012) Alexandra Thiel et al.   HELICOBACTER

PI3K/AKT/mTOR Inhibitors in Patients With Breast and Gynecologic Malignancies HarboringPIK3CAMutations

(2012) Filip Janku et al.   JOURNAL OF CLINICAL ONCOLOGY

Can the incidence of gastric cancer be reduced in the new century?

(2012) Ye Hu et al.   Journal of Digestive Diseases

Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9–22: Effects on the cell apoptosis through mitochondrial-related and ER stress pathway

(2012) Chih-I Liu et al.   Journal of Proteomics

Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells

(2012) Choo-Aun Neoh et al.   Marine Drugs

Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

(2012) Tzu-Rong Su et al.   Marine Drugs

MAP kinases and histone modification

(2012) T. Suganuma et al.   Journal of Molecular Cell Biology

Pituitary adenylate cyclase-activating polypeptide protects astroglial cells against oxidative stress-induced apoptosis

(2011) Olfa Masmoudi-Kouki et al.   JOURNAL OF NEUROCHEMISTRY

Proteomic Analysis of Anti-Tumor Effects of 11-Dehydrosinulariolide on CAL-27 Cells

(2011) Chih-I Liu et al.   Marine Drugs

An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells

(2011) Ching-Chyuan Su et al.   Marine Drugs

Role of Bcl-2 family proteins and caspases in the regulation of apoptosis

(2011) Mohammad Shamsul Ola et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

IRF-2 is over-expressed in pancreatic cancer and promotes the growth of pancreatic cancer cells

(2011) Lei Cui et al.   TUMOR BIOLOGY

Trend in gastric cancer: 35 years of surgical experience in Japan

(2011) Keishi Yamashita   WORLD JOURNAL OF GASTROENTEROLOGY

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft CoralCladiella pachyclados

(2010) Hossam M. Hassan et al.   JOURNAL OF NATURAL PRODUCTS

Effects of Pituitary Adenylate Cyclase Activating Polypeptide on the Survival and Signal Transduction Pathways in Human Choriocarcinoma Cells

(2009) A. Boronkai et al.   Annals of the New York Academy of Sciences

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Mechanisms of neuronal death in disease: defining the models and the players

(2008) Elena M. Ribe et al.   BIOCHEMICAL JOURNAL

Tumour cell survival signalling by the ERK1/2 pathway

(2008) K Balmanno et al.   CELL DEATH AND DIFFERENTIATION

MAPKs as Mediators of Cell Fate Determination: an Approach to Neurodegenerative Diseases

(2008) G. Tredici et al.   CURRENT MEDICINAL CHEMISTRY

Involvement of endoplasmic reticulum in paclitaxel‐induced apoptosis

(2008) Pei‐Chun Liao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Isolation, Biological Significance, Synthesis, and Cytotoxic Evaluation of New Natural Parathiosteroids A−C and Analogues from the Soft CoralParagorgiasp.

(2008) Javier Jesús Poza et al.   JOURNAL OF ORGANIC CHEMISTRY

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory

(2003) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY