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Title
Parkinson’s disease mouse models in translational research
Authors
Keywords
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Journal
MAMMALIAN GENOME
Volume 22, Issue 7-8, Pages 401-419
Publisher
Springer Nature
Online
2011-05-10
DOI
10.1007/s00335-011-9330-x
References
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Note: Only part of the references are listed.- Drosophila melanogaster in the Study of Human Neurodegeneration
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