标题
Parkinson’s disease mouse models in translational research
作者
关键词
-
出版物
MAMMALIAN GENOME
Volume 22, Issue 7-8, Pages 401-419
出版商
Springer Nature
发表日期
2011-05-10
DOI
10.1007/s00335-011-9330-x
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Drosophila melanogaster in the Study of Human Neurodegeneration
- (2012) Frank Hirth CNS & Neurological Disorders-Drug Targets
- Parkinsonian Rotenone Mouse Model: Reevaluation of Long-Term Administration of Rotenone in C57BL/6 Mice
- (2011) Masatoshi Inden et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background
- (2011) Kavita Prasad et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease
- (2011) Cameron H. Good et al. FASEB JOURNAL
- When Does Parkinson Disease Start?
- (2010) Rodolfo Savica et al. ARCHIVES OF NEUROLOGY
- Altered expression of neuronal nitric oxide synthase in weaver mutant mice
- (2010) Roberta Cavalcanti-Kwiatkoski et al. BRAIN RESEARCH
- Deep Brain Stimulation in Clinical Practice and in Animal Models
- (2010) C Hamani et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Diseases as network perturbations
- (2010) Antonio del Sol et al. CURRENT OPINION IN BIOTECHNOLOGY
- Trichloroethylene and Parkinson’s disease: dissolving the puzzle
- (2010) Samuel M Goldman Expert Review of Neurotherapeutics
- Proteomics in Parkinson’s disease: current trends, translational snags and future possibilities
- (2010) Garima Srivastava et al. Expert Review of Proteomics
- Understanding the molecular basis of Parkinson’s disease, identification of biomarkers and routes to therapy
- (2010) Philip A Robinson Expert Review of Proteomics
- Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network
- (2010) Atsushi Tanaka FEBS LETTERS
- Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes
- (2010) Yien-Ming Kuo et al. HUMAN MOLECULAR GENETICS
- Hyperexcitable Substantia Nigra Dopamine Neurons in PINK1- and HtrA2/Omi-Deficient Mice
- (2010) Matthew W. Bishop et al. JOURNAL OF NEUROPHYSIOLOGY
- Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S
- (2010) X. Li et al. JOURNAL OF NEUROSCIENCE
- QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains
- (2010) Akinori Nishi et al. MAMMALIAN GENOME
- Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
- (2010) Coro Paisán-Ruiz et al. MOVEMENT DISORDERS
- The role of parkin in familial and sporadic Parkinson's disease
- (2010) Ted M. Dawson et al. MOVEMENT DISORDERS
- Molecular and clinical prodrome of Parkinson disease: implications for treatment
- (2010) Anthony H. V. Schapira et al. Nature Reviews Neurology
- Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
- (2010) H.L. Melrose et al. NEUROBIOLOGY OF DISEASE
- Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
- (2010) B. Winner et al. NEUROBIOLOGY OF DISEASE
- Single-Photon Emission Computed Tomography in Diagnosis and Differential Diagnosis of Parkinson’s Disease
- (2010) Ioannis U. Isaias et al. Neurodegenerative Diseases
- Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus
- (2010) E.- K. Tan et al. NEUROLOGY
- Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism
- (2010) H. Yoshino et al. NEUROLOGY
- -Synuclein triple knockout mice reveal age-dependent neuronal dysfunction
- (2010) B. Greten-Harrison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- An energy systems approach to Parkinson's disease
- (2010) Peter Wellstead et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Predictive, preventive, personalized and participatory medicine: back to the future
- (2010) Charles Auffray et al. Genome Medicine
- Pro-Survival Role for Parkinson's Associated Gene DJ-1 Revealed in Trophically Impaired Dopaminergic Neurons
- (2010) Liviu Aron et al. PLOS BIOLOGY
- Threonine 53 in α-synuclein is conserved in long-living non-primate animals
- (2009) Knud Larsen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- G protein-coupled receptor kinase 5, overexpressed in the α-synuclein up-regulation model of Parkinson's disease, regulates bcl-2 expression
- (2009) Peng Liu et al. BRAIN RESEARCH
- Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
- (2009) Vanessa A. Morais et al. EMBO Molecular Medicine
- Dopamine Transporter Genetic Variants and Pesticides in Parkinson’s Disease
- (2009) Beate R. Ritz et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Perspectives on recent advances in the understanding and treatment of Parkinson’s disease
- (2009) A. H. Schapira et al. EUROPEAN JOURNAL OF NEUROLOGY
- Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein
- (2009) Franz Marxreiter et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Forebrain overexpression of α-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption
- (2009) Youngshin Lim et al. EXPERIMENTAL NEUROLOGY
- Lovastatin ameliorates α-synuclein accumulation and oxidation in transgenic mouse models of α-synucleinopathies
- (2009) Andrew O. Koob et al. EXPERIMENTAL NEUROLOGY
- Molecular pathogenesis of Parkinson disease: insights from genetic studies
- (2009) Thomas Gasser EXPERT REVIEWS IN MOLECULAR MEDICINE
- MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease
- (2009) D. Galter et al. GENES BRAIN AND BEHAVIOR
- GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling
- (2009) B. Giovannone et al. HUMAN MOLECULAR GENETICS
- Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons
- (2009) Dong-Youn Hwang et al. JOURNAL OF NEUROCHEMISTRY
- Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice
- (2009) Tohru Kitada et al. JOURNAL OF NEUROCHEMISTRY
- Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats
- (2009) Mei Liu et al. JOURNAL OF NEUROCHEMISTRY
- Lewy Body Pathology in Normal Elderly Subjects
- (2009) William R. Markesbery et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
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- (2009) A. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Nonmotor Symptoms of Parkinson's Disease Revealed in an Animal Model with Reduced Monoamine Storage Capacity
- (2009) T. N. Taylor et al. JOURNAL OF NEUROSCIENCE
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- (2009) X.-H. Lu et al. JOURNAL OF NEUROSCIENCE
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- (2009) R. Nass et al. MOLECULAR INTERVENTIONS
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- (2009) João Daher et al. Molecular Neurodegeneration
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
- (2009) Yanping Li et al. NATURE NEUROSCIENCE
- Selective noradrenergic vulnerability in alpha-synuclein transgenic mice
- (2009) Evangelos Sotiriou et al. NEUROBIOLOGY OF AGING
- Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease
- (2009) Dietrich Haubenberger et al. NEUROBIOLOGY OF AGING
- Genomic and proteomic biomarkers for Parkinson disease
- (2009) T. Gasser NEUROLOGY
- "Disease-modification" trials in Parkinson disease: Target populations, endpoints and study design
- (2009) O. Rascol NEUROLOGY
- The Parkinson chimera
- (2009) A. J. Lees NEUROLOGY
- Course in Parkinson disease subtypes: A 39-year clinicopathologic study
- (2009) A. H. Rajput et al. NEUROLOGY
- Diagnosis and the premotor phase of Parkinson disease
- (2009) E. Tolosa et al. NEUROLOGY
- Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
- (2009) Xian Lin et al. NEURON
- Abnormal colonic motility in mice overexpressing human wild-type α-synuclein
- (2009) Lixin Wang et al. NEUROREPORT
- Nuclear and neuritic distribution of serine-129 phosphorylated α-synuclein in transgenic mice
- (2009) H. Schell et al. NEUROSCIENCE
- Alterations in corticostriatal synaptic plasticity in mice overexpressing human α-synuclein
- (2009) J.B. Watson et al. NEUROSCIENCE
- Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity
- (2009) Xiaomin Su et al. NEUROTOXICITY RESEARCH
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- The MitoPark Mouse – An animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons
- (2009) Mats I. Ekstrand et al. PARKINSONISM & RELATED DISORDERS
- A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P+A53T transgenic mice
- (2009) Kazuhiko Ono et al. PARKINSONISM & RELATED DISORDERS
- A timeline for Parkinson's disease
- (2009) Christopher H. Hawkes et al. PARKINSONISM & RELATED DISORDERS
- Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration
- (2009) Suzana Gispert et al. PLoS One
- R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
- (2009) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arvid Carlsson: An Early Pioneer in Translational Medicine
- (2009) J. K. Andersen Science Translational Medicine
- A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice—as a mouse model for Parkinson’s disease
- (2008) Chisato Takazawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Motor impairment and aberrant production of neurochemicals in human α-synuclein A30P+A53T transgenic mice with α-synuclein pathology
- (2008) Masaki Ikeda et al. BRAIN RESEARCH
- Fine-mapping and candidate gene investigation within the PARK10 locus
- (2008) Kristoffer Haugarvoll et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Olfactory deficits in mice overexpressing human wildtype -synuclein
- (2008) Sheila M. Fleming et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- α-Synuclein transgenic mice exhibit reduced anxiety-like behaviour
- (2008) Sonia George et al. EXPERIMENTAL NEUROLOGY
- Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin
- (2008) G. Martella et al. EXPERIMENTAL NEUROLOGY
- Genomewide association study for susceptibility genes contributing to familial Parkinson disease
- (2008) Nathan Pankratz et al. HUMAN GENETICS
- Transgenic Mice Overexpressing Tyrosine-to-Cysteine Mutant Human α-Synuclein
- (2008) Wenbo Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuroproteomics as a promising tool in Parkinson’s disease research
- (2008) Ilse S. Pienaar et al. JOURNAL OF NEURAL TRANSMISSION
- Aging and α-synuclein affect synaptic plasticity in the dentate gyrus
- (2008) Irina Gureviciene et al. JOURNAL OF NEURAL TRANSMISSION
- Effects of UCH-L1 on α-synuclein over-expression mouse model of Parkinson’s disease
- (2008) Toru Yasuda et al. JOURNAL OF NEUROCHEMISTRY
- Parkinson's disease: clinical features and diagnosis
- (2008) J Jankovic JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease
- (2008) S. Nuber et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation and Oxidation/Nitration of -Synuclein Linked to Dopaminergic Neurodegeneration
- (2008) H.-M. Gao et al. JOURNAL OF NEUROSCIENCE
- Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
- (2008) T. C. Frank-Cannon et al. JOURNAL OF NEUROSCIENCE
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease
- (2008) Hiroshige Fujishiro et al. MOVEMENT DISORDERS
- The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?
- (2008) Christopher H. Hawkes MOVEMENT DISORDERS
- FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome
- (2008) A. D. Fonzo et al. NEUROLOGY
- Behavioural and neurochemical response of α-synuclein A30P transgenic mice to the effects of L-DOPA
- (2008) Mari Oksman et al. NEUROPHARMACOLOGY
- Modeling PD pathogenesis in mice: Advantages of a chronic MPTP protocol
- (2008) Gloria E. Meredith et al. PARKINSONISM & RELATED DISORDERS
- Strengths and limitations of genetic mouse models of Parkinson's disease
- (2008) Marie-Francoise Chesselet et al. PARKINSONISM & RELATED DISORDERS
- PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
- (2008) Alison Wood-Kaczmar et al. PLoS One
- Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
- (2008) C. A. Gautier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity
- (2007) Don M. Gash et al. ANNALS OF NEUROLOGY
- Dopamine receptor agonists reverse behavioral abnormalities of α-synuclein transgenic mouse, a new model of Parkinson's disease
- (2007) Masaki Wakamatsu et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Mutant α-synuclein exacerbates age-related decrease of neurogenesis
- (2007) Beate Winner et al. NEUROBIOLOGY OF AGING
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
- Transcriptional dysregulation in a transgenic model of Parkinson disease
- (2007) Talene A. Yacoubian et al. NEUROBIOLOGY OF DISEASE
- The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK–PD experiments
- (2007) Paulien G.M. Ravenstijn et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
- (2006) Masaki Wakamatsu et al. NEUROBIOLOGY OF AGING
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