☆ 4.2 Editorial Material

Arterial spin labeling: its time is now

MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE (2012)

Journal

MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Volume 25, Issue 2, Pages 75-77

Publisher

SPRINGER

DOI: 10.1007/s10334-012-0309-8

Keywords

-

Categories

Radiology, Nuclear Medicine & Medical Imaging

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Radiology, Nuclear Medicine & Medical Imaging

Time-encoded pseudo-continuous arterial spin labeling: Increasing SNR in ASL dynamic angiography

Joseph G. Woods, S. Sophie Schauman, Mark Chiew, Michael A. Chappell, Thomas W. Okell

Summary: This study investigates the use of time-encoded arterial spin labeling (ASL) angiography to improve signal-to-noise ratio (SNR) by using larger flip angles. The results show that the time-encoded protocol significantly increases SNR compared to conventional protocols, and the use of variable flip angles further improves SNR. Optimization of background suppression can lead to additional improvements in SNR.

MAGNETIC RESONANCE IN MEDICINE (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Arterial Transit Time-Based Multidelay Combination Strategy Improves Arterial Spin Labeling Cerebral Blood Flow Measurement Accuracy in Severe Steno-Occlusive Diseases

Shiori Amemiya, Yusuke Watanabe, Naoyuki Takei, Tsuyoshi Ueyama, Satoru Miyawaki, Satoshi Koizumi, Seiji Kato, Hidemasa Takao, Osamu Abe, Nobuhito Saito

Summary: The study found that in severe steno-occlusive diseases, the Combo strategy using ATT correction can improve CBF measurement accuracy, and VS significantly enhances CBF measurement accuracy in standard protocol and in moyamoya patients for the Combo.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2022)

Add to Collection

Article Clinical Neurology

Arterial Spin-Labeling Perfusion for PHACE Syndrome

M. D. Mamlouk, A. Vossough, L. Caschera, M. Maheshwari, C. P. Hess

Summary: This study reviewed arterial spin-labeling imaging in 41 patients with PHACE syndrome and found that 24% of patients had decreased CBF signal. The most common pattern of CBF signal decrease was in the anterior circulation, with all patients showing corresponding arterial anomalies.

AMERICAN JOURNAL OF NEURORADIOLOGY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Histogram-Based Analysis of Low- and High-Grade Glioma and Its Surrounding Edema Using Arterial Spin Labeling Magnetic Resonance Imaging

Thomas Lindner, Lasse Duehrsen, Anna Andriana Kyselyova, Wiebke Entelmann, Luis Hau, Jens Fiehler

Summary: This study aimed to find biomarkers for the pathological diagnosis, grading, MGMT, and mutation status of gliomas as well as the analysis of tumor-surrounding edema through histogram analysis of ASL data. The results showed significant findings for pathological diagnosis and grading, but not for MGMT status or mutation. The differentiation between tumor and edema showed highly significant results, but no differences were found between edema and perfusion on the contralateral hemisphere.

APPLIED SCIENCES-BASEL (2023)

Add to Collection

Review Oncology

Pseudocontinuous Arterial Spin Labeling: Clinical Applications and Usefulness in Head and Neck Entities

Fumine Tanaka, Maki Umino, Masayuki Maeda, Ryohei Nakayama, Katsuhiro Inoue, Ryota Kogue, Makoto Obara, Hajime Sakuma

Summary: This article introduces the clinical value of arterial spin labeling (ASL) techniques in the diagnosis of head and neck lesions, highlighting the advantages of pseudocontinuous arterial spin labeling (pCASL) with a three-dimensional readout method for the diagnosis of inflammatory lesions, hypervascular lesions, and neoplasms, as well as for evaluating squamous cell carcinoma (SCC) treatment responses and predicting SCC prognosis.

CANCERS (2022)

Add to Collection

Review Radiology, Nuclear Medicine & Medical Imaging

Arterial Spin Labeling Applications in Pediatric and Adult Neurologic Disorders

Sven Bambach, Mark Smith, P. Pearse Morris, Norbert G. Campeau, Mai-Lan Ho

Summary: Arterial spin labeling (ASL) is a noncontrast MRI technique used for quantitative evaluation of brain perfusion. This article discusses advanced applications of ASL across the lifespan, presenting case examples from children and adults with various pathologies. The article highlights the subtleties and pitfalls of ASL interpretation.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Automated generation of cerebral blood flow and arterial transit time maps from multiple delay arterial spin-labeled MRI

Nicholas J. Luciw, Zahra Shirzadi, Sandra E. Black, Maged Goubran, Bradley J. MacIntosh

Summary: This study developed and evaluated a deep learning approach to estimate CBF and ATT from multiple PLD ASL MRI. Different convolutional neural network architectures were trained and compared, and the U-Net model showed better performance. The U-Net model had lower MAE on both training and test data, and demonstrated good generalizability.

MAGNETIC RESONANCE IN MEDICINE (2022)

Add to Collection

Article Neurosciences

Global Functional Connectivity at Rest Is Associated with Attention: An Arterial Spin Labeling Study

Shichun Chen, Yakun Zhang, Zongpai Zhang, Tony D. Zhou, Wenna Duan, George Weinschenk, Wen-Ming Luh, Adam K. Anderson, Weiying Dai

Summary: Markers of attention vary among individuals and understanding their neural mechanisms is important for studying attention-related brain disorders. This study examined the relationship between brain connectivity and attention markers using resting-state MRI and event-related potentials.

BRAIN SCIENCES (2023)

Add to Collection

Article Neurosciences

Affine image registration of arterial spin labeling MRI using deep learning networks

Zongpai Zhang, Huiyuan Yang, Yanchen Guo, Nicolas R. Bolo, Matcheri Keshavan, Eve DeRosa, Adam K. Anderson, David C. Alsop, Lijun Yin, Weiying Dai

Summary: In this study, a CNN-based affine registration network (ARN) was proposed for registration of low-SNR 3D ASL perfusion image time series, and its performance was compared with the state-of-the-art SPM algorithm. The results showed that the ARN method outperformed SPM in terms of registration accuracy and speed, and can be generalized to different scanners and image resolutions of ASL perfusion images.

NEUROIMAGE (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Arterial spin labeling of nasopharyngeal carcinoma shows early therapy response

Jun Liu, Juan Zhu, Yaxian Wang, Fei Wang, Hualin Yang, Nan Wang, Qingyun Chu, Qing Yang

Summary: This study demonstrates the value of arterial spin labeling (ASL) perfusion imaging in assessing the early efficacy of chemoradiotherapy for nasopharyngeal carcinoma (NPC). By investigating tumor blood flow parameters and their correlation with tumor atrophy rate, it is possible to predict the sensitivity to chemoradiotherapy and the presence of residual tumors.

INSIGHTS INTO IMAGING (2022)

Add to Collection

Review Radiology, Nuclear Medicine & Medical Imaging

Arterial Spin Labeling-Based MR Angiography for Cerebrovascular Diseases: Principles and Clinical Applications

Osamu Togao, Makoto Obara, Koji Yamashita, Kazufumi Kikuchi, Tatsuhiro Wada, Hiroo Murazaki, Koichi Arimura, Ataru Nishimura, Nobutaka Horie, Kim van de Ven, Marc Van Cauteren, Kousei Ishigami

Summary: Arterial spin labeling (ASL) is a noninvasive imaging technique used for brain perfusion imaging and intracranial magnetic resonance angiography (MRA). It does not require contrast agents and overcomes some disadvantages of other imaging techniques. Various ASL techniques are available, including pulsed ASL and pseudo-continuous ASL. New methods such as velocity-selective ASL and acceleration-selective ASL have also been developed. Silent MRA and ultrashort echo-time MRA are suitable for patients with metallic devices. Vessel-selective 4D ASL MRA can provide DSA-like images.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Blood-Brain Barrier Permeability to Water Measured Using Multiple Echo Time Arterial Spin Labeling MRI in the Aging Human Brain

Amnah Mahroo, Simon Konstandin, Matthias Guenther

Summary: This study used noninvasive multiple-echo-time arterial spin labeling MRI to investigate age-related changes in the blood-brain barrier permeability to water. The results showed that older individuals have increased permeability of the blood-brain barrier compared to younger individuals, suggesting a decline in barrier integrity with aging.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Arterial transit artifacts on arterial spin labeling MRI can predict cerebral hyperperfusion after carotid endarterectomy: an initial study

Xiaoyuan Fan, Zhentao Zuo, Tianye Lin, Zhichao Lai, Hui You, Jianxun Qu, Juan Wei, Bao Liu, Feng Feng

Summary: The study aimed to investigate whether preoperative arterial spin labeling (ASL) MRI can predict cerebral hyperperfusion after carotid endarterectomy (CEA) in patients with carotid stenosis. The study found that ASL can non-invasively predict cerebral hyperperfusion after CEA in patients with carotid stenosis based on the presence of arterial transit artifacts (ATAs).

EUROPEAN RADIOLOGY (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Estimation of Cerebral Blood Flow and Arterial Transit Time From Multi-Delay Arterial Spin Labeling MRI Using a Simulation-Based Supervised Deep Neural Network

Shota Ishida, Makoto Isozaki, Yasuhiro Fujiwara, Naoyuki Takei, Masayuki Kanamoto, Hirohiko Kimura, Tetsuya Tsujikawa

Summary: Using simulation-based supervised DNNs can reduce the effects of Rician noise on ASL parameter estimation and compute unbiased CBF and ATT values. The study found that DNN outperforms conventional methods in terms of accuracy, precision, and noise immunity.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2023)

Add to Collection

Article Medicine, General & Internal

Using arterial spin labeling blood flow and its histogram analysis to distinguish early-stage nasopharyngeal carcinoma from lymphoid hyperplasia

Bohan Xiao, Peiguo Wang, Yingru Zhao, Ying Liu, Zhaoxiang Ye

Summary: Arterial spin labeling (ASL) blood flow and its histogram analysis can differentiate early-stage nasopharyngeal carcinoma from nasopharyngeal lymphoid hyperplasia. In this study, variance in the BF histogram parameters was identified as the unique independent predictor of outcome.

MEDICINE (2021)

Add to Collection

Article Endocrinology & Metabolism

Regional and depth-dependence of cortical blood-flow assessed with high-resolution Arterial Spin Labeling (ASL)

Manuel Taso, Fanny Munsch, Li Zhao, David C. Alsop

Summary: High-resolution imaging methods using ASL and T-1 mapping highlight the importance of spatial resolution and tissue heterogeneity in measuring cortical cerebral blood flow. Regional analysis reveals significant differences across cortical regions, with depth-dependent T-1 variation complicating interpretation of ASL signal. This has implications for accurate CBF quantification, especially at lower resolutions.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2021)

Add to Collection

Article Gastroenterology & Hepatology

Priming of Sorafenib Prior to Radiofrequency Ablation Does Not Increase Treatment Effect in Hepatocellular Carcinoma

Bruno Bockorny, Andrea J. Bullock, Thomas A. Abrams, Salomao Faintuch, David C. Alsop, S. Nahum Goldberg, Muneeb Ahmed, Rebecca A. Miksad

Summary: The study evaluated the efficacy of short-course sorafenib prior to RFA for HCC tumors and found that sorafenib did not increase the size of the ablation zone achieved with RFA, but significantly decreased tumor blood perfusion. Sorafenib was well-tolerated with no grade 4 toxicity observed. Future research should investigate alternative antiangiogenic strategies to enhance RFA efficacy.

DIGESTIVE DISEASES AND SCIENCES (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

T-1D-weighted ihMT imaging - Part II. Investigating the long- and short-T-1D components correlation with myelin content. Comparison with R-1 and the macromolecular proton fraction

Andreea Hertanu, Lucas Soustelle, Julie Buron, Julie Le Priellec, Myriam Cayre, Arnaud Le Troter, Gopal Varma, David C. Alsop, Pascale Durbec, Olivier M. Girard, Guillaume Duhamel

Summary: This study investigated the correlation between long- and short-T-1D components and myelin content using ihMT high-pass and band-pass T-1D filters, and compared the specificity of ihMT, R-1, and MPF for myelin specific imaging. The results showed that long-T(1D) components had higher specificity to myelination compared to short components. In contrast, focusing on short-T(1D) components within a narrow range led to lower specificity. The study suggests that ihMT high-pass T-1D filters could be used as an MRI biomarker for myelin content.

MAGNETIC RESONANCE IN MEDICINE (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

A strategy to reduce the sensitivity of inhomogeneous magnetization transfer (ihMT) imaging to radiofrequency transmit field variations at 3 T

Lucas Soustelle, Thomas Troalen, Andreea Hertanu, Samira Mchinda, Jean-Philippe Ranjeva, Maxime Guye, Gopal Varma, David C. Alsop, Guillaume Duhamel, Olivier M. Girard

Summary: Concentrating RF saturation energy in ihMT-GRE sequences mitigates the sensitivity of ihMTR to B1+ variations, allowing for clinical-ready ihMT imaging at 3 T. Under optimal conditions, 73% of WM voxels presented delta(ihMTR) below 10%. Reproducibility analysis showed minimal systematic bias and high correlation between test and retest experiments.

MAGNETIC RESONANCE IN MEDICINE (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

T1D-weighted ihMT imaging - Part I. Isolation of long- and short-T1D components by T1D-filtering

Andreea Hertanu, Lucas Soustelle, Arnaud Le Troter, Julie Buron, Julie Le Priellec, Victor N. D. Carvalho, Myriam Cayre, Pascale Durbec, Gopal Varma, David C. Alsop, Olivier M. Girard, Guillaume Duhamel

Summary: This study investigated T-1D-filtering methods for isolating different ranges of T-1D components based on their microstructural properties. The results showed that high RF power and low duty-cycle ihMT filters could successfully isolate long-T-1D and short-T-1D components in the brain.

MAGNETIC RESONANCE IN MEDICINE (2022)

Add to Collection

Meeting Abstract Endocrinology & Metabolism

Imaging Pancreatic Blood Flow during Stimulation of Insulin Secretion in Humans

Donald C. Simonson, Manuel Taso, Colleen Mcgrath, Stephanie A. Waldman, Fotini Papadopoulou, David C. Alsop

DIABETES (2022)

Add to Collection

Review Radiology, Nuclear Medicine & Medical Imaging

Velocity-selective arterial spin labeling perfusion MRI: A review of the state of the art and recommendations for clinical implementation

Qin Qin, David C. Alsop, Divya S. Bolar, Luis Hernandez-Garcia, James Meakin, Dapeng Liu, Krishna S. Nayak, Sophie Schmid, Matthias J. P. van Osch, Eric C. Wong, Joseph G. Woods, Greg Zaharchuk, Moss Y. Zhao, Zungho Zun, Jia Guo

Summary: This review article provides an overview of the current status of velocity-selective arterial spin labeling (VSASL) perfusion MRI and discusses its concepts, implementation, clinical applications, and technical challenges.

MAGNETIC RESONANCE IN MEDICINE (2022)

Add to Collection

Review Biophysics

Inhomogeneous magnetization transfer imaging: Concepts and directions for further development

David C. Alsop, Ece Ercan, Olivier M. Girard, Alex L. Mackay, Carl A. Michal, Gopal Varma, Elena Vinogradov, Guillaume Duhamel

Summary: Off-resonance radio frequency irradiation can induce the ordering of proton spins in the dipolar fields of their neighbors, in molecules with restricted mobility. This dipolar order decays with a characteristic relaxation time, T-1D, that is very different from the T-1 and T-2 relaxation of the nuclear alignment with the main magnetic field. Inhomogeneous magnetization transfer (ihMT) imaging is a refinement of magnetization transfer (MT) imaging that isolates the MT signal dependence on dipolar order relaxation times within motion-constrained molecules.

NMR IN BIOMEDICINE (2023)

Add to Collection

Article Clinical Neurology

The Boston ASL Template and Simulator: Initial development and implementation

Manuel Taso, Fanny Munsch, David C. Alsop

Summary: This study proposes an initial development of an ASL adult template based on high-resolution fast spin echo acquisitions and builds a multi-contrast template. Examples of data registration using ASL data acquired with different sequences are provided, and a simulator allowing the generation of synthetic ASL contrasts is proposed.

JOURNAL OF NEUROIMAGING (2022)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Fast-spin-echo versus rapid gradient-echo for 3D magnetization-prepared acquisitions: Application to inhomogeneous magnetization transfer

Manuel Taso, Fanny Munsch, Olivier M. Girard, Guillaume Duhamel, David C. Alsop, Gopal Varma

Summary: This study compared the benefits of fast spin echo (FSE) imaging with rapid gradient-echo (RAGE) in magnetization-prepared inhomogeneous magnetization transfer (ihMT) imaging. The results showed that FSE imaging generally has higher signal-to-noise ratio (SNR) compared to gradient-echo imaging, but it also has higher physiological noise. However, an inversion-recovery-based cerebrospinal fluid (CSF) suppression was shown to be efficient in mitigating the effects of CSF motion.

MAGNETIC RESONANCE IN MEDICINE (2023)

Add to Collection

Review Radiology, Nuclear Medicine & Medical Imaging

Primary Multiparametric Quantitative Brain MRI: State-of-the-Art Relaxometric and Proton Density Mapping Techniques

Hernan Jara, Osamu Sakai, Ezequiel Farrher, Ana-Maria Oros-Peusquens, N. Jon Shah, David C. Alsop, Kathryn E. Keenan

Summary: This review focuses on the primary subset of quantitative MRI parameters in brain multiparametric quantitative MRI (MP-qMRI) and summarizes the advances and areas that need further investigation. It also introduces three emerging applications of MP-qMRI.

RADIOLOGY (2022)

Add to Collection

Article Multidisciplinary Sciences

ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Patricia Clement, Marco Castellaro, Thomas W. Okell, David L. Thomas, Pieter Vandemaele, Sara Elgayar, Aaron Oliver-Taylor, Thomas Kirk, Joseph G. Woods, Sjoerd B. Vos, Joost P. A. Kuijer, Eric Achten, Matthias J. P. van Osch, John A. Detre, Hanzhang Lu, David C. Alsop, Michael A. Chappell, Luis Hernandez-Garcia, Jan Petr, Henk J. M. M. Mutsaerts

Summary: ASL-BIDS is a standardized method for ASL data storage that can improve the reproducibility and data sharing of ASL research.

SCIENTIFIC DATA (2022)

Add to Collection

Article Neurosciences

Inhomogeneous Magnetization Transfer (ihMT) imaging in the acute cuprizone mouse model of demyelination/remyelination

Andreea Hertanu, Lucas Soustelle, Julie Buron, Julie Le Priellec, Myriam Cayre, Arnaud Le Troter, Valentin H. Prevost, Jean-Philippe Ranjeva, Gopal Varma, David C. Alsop, Pascale Durbec, Olivier M. Girard, Guillaume Duhamel

Summary: This study investigated the association of ihMT signals with demyelination and remyelination in the acute cuprizone mouse model using multimodal MRI. The results showed that the ihMT high-pass T1D-filters were sensitive markers of demyelination and remyelination, and correlated well with histology. The ihMT band-pass T1D-filter was less sensitive to myelin changes and may be influenced by other pathological processes.

NEUROIMAGE (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Quantitative magnetization transfer MRI unbiased by on-resonance saturation and dipolar order contributions

Lucas Soustelle, Thomas Troalen, Andreea Hertanu, Jean-Philippe Ranjeva, Maxime Guye, Gopal Varma, David C. Alsop, Guillaume Duhamel, Olivier M. Girard

Summary: The purpose of this study is to demonstrate the bias in quantitative MT (qMT) measures caused by dipolar order and on-resonance saturation (ONRS) effects in MT spoiled gradient-recalled (SPGR) acquisitions. The researchers propose changes to the acquisition and analysis strategies to remove these biases and improve the accuracy and reproducibility of qMT-SPGR studies.

MAGNETIC RESONANCE IN MEDICINE (2023)

Add to Collection

Article Clinical Neurology

Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging

Yuta Katsumi, Bonnie Wong, Michele Cavallari, Tamara G. Fong, David C. Alsop, Joseph M. Andreano, Nicole Carvalho, Michael Brickhouse, Richard Jones, Towia A. Libermann, Edward R. Marcantonio, Eva Schmitt, Mouhsin M. Shafi, Alvaro Pascual-Leone, Thomas Travison, Lisa Feldman Barrett, Sharon K. Inouye, Bradford C. Dickerson, Alexandra Touroutoglou

Summary: This study investigates the factors that may confer resilience to postoperative delirium in older adults and finds that SuperAging, characterized by superior memory function, is associated with a lower incidence and severity of delirium. It also suggests that the baseline cortical thickness of the anterior mid-cingulate cortex may serve as a potential biomarker of resilience to delirium.

BRAIN COMMUNICATIONS (2022)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.