Members of the receptor for advanced glycation end products axis as potential therapeutic targets in patients with lupus nephritis

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

(2014) Y. Sha et al.   JOURNAL OF IMMUNOLOGY

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-  Production in Human Monocytes

(2014) J. H. Youn et al.   JOURNAL OF IMMUNOLOGY

Immune complexes activate human endothelium involving the cell-signaling HMGB1-RAGE axis in the pathogenesis of lupus vasculitis

(2013) Wenping Sun et al.   LABORATORY INVESTIGATION

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies

(2013) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus

(2013) H. Tyden et al.   RHEUMATOLOGY

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

The Plasma Level of Soluble Receptor for Advanced Glycation End Products is Decreased in Patients with Systemic Lupus Erythematosus

(2012) C.-Y. Ma et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis

(2012) Agneta Zickert et al.   ARTHRITIS RESEARCH & THERAPY

HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation

(2011) José Augusto Nogueira-Machado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

High-mobility group box 1 represents a potential marker of disease activity and novel therapeutic target in systemic lupus erythematosus

(2011) V. Urbonaviciute et al.   JOURNAL OF INTERNAL MEDICINE

Clinical significance of serum sRAGE and esRAGE in women with normal pregnancy and preeclampsia

(2011) Jae-Hyun Kwon et al.   JOURNAL OF PERINATAL MEDICINE

Down-Regulated NOD2 by Immunosuppressants in Peripheral Blood Cells in Patients with SLE Reduces the Muramyl Dipeptide-Induced IL-10 Production

(2011) Shui-Lian Yu et al.   PLoS One

High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus

(2011) Deena A Abdulahad et al.   ARTHRITIS RESEARCH & THERAPY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

What Is the Significance of Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products in Liver Steatosis in Obese Prepubertal Children?

(2010) Ebe D'Adamo et al.   ANTIOXIDANTS & REDOX SIGNALING

HMGB1 in systemic lupus Erythematosus: Its role in cutaneous lesions development

(2010) D.A. Abdulahad et al.   AUTOIMMUNITY REVIEWS

Enhanced expression of receptor for advanced glycation end-products is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes

(2010) Xystus H. L. Tam et al.   CLINICAL SCIENCE

High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

(2010) Isabel García-Arnandis et al.   ARTHRITIS RESEARCH & THERAPY

Soluble Forms of RAGE in Human Diseases: Clinical and Therapeutical Implications

(2009) Francesca Santilli et al.   CURRENT MEDICINAL CHEMISTRY

RAGE signaling in inflammation and arterial aging

(2009) Li Lin   Frontiers in Bioscience-Landmark

Soluble forms of RAGE in internal medicine

(2009) Natale Vazzana et al.   Internal and Emergency Medicine

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

(2009) Edward Parkin et al.   JOURNAL OF NEUROCHEMISTRY

RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation

(2009) Louis J Sparvero et al.   Journal of Translational Medicine

Accuracy of the Flow Convergence Method for Quantification of Aortic Regurgitation in Patients With Central Versus Eccentric Jets

(2008) Anne-Catherine Pouleur et al.   AMERICAN JOURNAL OF CARDIOLOGY

Calcium-regulated intramembrane proteolysis of the RAGE receptor

(2008) Arnaud Galichet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

(2008) Angela Raucci et al.   FASEB JOURNAL

Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases

(2008) Ling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts

(2008) H. L. Nienhuis et al.   RHEUMATOLOGY