Targeted therapies in systemic lupus erythematosus

B-cell-depleting Therapy in Systemic Lupus Erythematosus

(2012) Manuel Ramos-Casals et al.   AMERICAN JOURNAL OF MEDICINE

Treatment of systemic lupus erythematosus: new advances in targeted therapy

(2012) Mindy S. Lo et al.   Annals of the New York Academy of Sciences

Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study

(2012) Brad H. Rovin et al.   ARTHRITIS AND RHEUMATISM

Abatacept for lupus nephritis: Alternative definitions of complete response support conflicting conclusions

(2012) David Wofsy et al.   ARTHRITIS AND RHEUMATISM

Emerging therapies for systemic lupus erythematosus — Focus on targeting interferon-alpha

(2012) Eben I. Lichtman et al.   CLINICAL IMMUNOLOGY

Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial

(2012) Ellen M Ginzler et al.   ARTHRITIS RESEARCH & THERAPY

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon   monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

(2011) J. T. Merrill et al.   ANNALS OF THE RHEUMATIC DISEASES

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Belimumab: A BLyS-Specific Inhibitor for the Treatment of Systemic Lupus Erythematosus

(2011) G J Dennis   CLINICAL PHARMACOLOGY & THERAPEUTICS

Current and novel therapeutics in the treatment of systemic lupus erythematosus

(2011) Cagri Yildirim-Toruner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Assessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER)

(2011) JT Merrill et al.   LUPUS

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade

(2010) G. K. Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

(2010) J. T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

(2010) Gabor G. Illei et al.   ARTHRITIS AND RHEUMATISM

Anti-CD40L Immune Complexes Potently Activate Platelets In Vitro and Cause Thrombosis in FCGR2A Transgenic Mice

(2010) L. Robles-Carrillo et al.   JOURNAL OF IMMUNOLOGY

Rituximab and lupus: Good in real life, bad in controlled trials. comment on the article by Lu et al

(2009) Manuel Ramos-Casals et al.   ARTHRITIS AND RHEUMATISM

A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus

(2009) Daniel J. Wallace et al.   ARTHRITIS AND RHEUMATISM

Novel evidence-based systemic lupus erythematosus responder index

(2009) Richard A. Furie et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

An exploratory dose-escalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus

(2009) C Pena-Rossi et al.   LUPUS

Rituximab in systemic lupus erythematosusA systematic review of off-label use in 188 cases

(2009) M Ramos-Casals et al.   LUPUS

Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus

(2009) Guillermo J. Pons-Estel et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-α–producing antigen-presenting cells

(2008) Bing Yan et al.   ARTHRITIS AND RHEUMATISM

Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: Are patients with systemic lupus erythematosus at particular risk?

(2008) Eamonn S. Molloy et al.   AUTOIMMUNITY REVIEWS

Novel molecular targets in the treatment of systemic lupus erythematosus

(2007) José C. Crispín et al.   AUTOIMMUNITY REVIEWS