Role of Toll-Like Receptor 4 in Mediating Multiorgan Dysfunction in Mice With Acetaminophen Induced Acute Liver Failure

Reduced Hepatic Injury in Toll-Like Receptor 4–Deficient Mice Following D-Galactosamine/Lipopolysaccharide-Induced Fulminant Hepatic Failure

(2012) Ziv Ben Ari et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure

(2012) James E. Fisher et al.   JOURNAL OF SURGICAL RESEARCH

The Unfolding Web of Innate Immune Dysregulation in Alcoholic Liver Injury

(2011) G. Szabo et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The systemic inflammatory response syndrome and sequential organ failure assessment scores are effective triage markers following paracetamol (acetaminophen) overdose

(2011) D. G. N. Craig et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The role of toll-like receptor-4 in the development of multi-organ failure following traumatic haemorrhagic shock and resuscitation

(2011) Lee J. McGhan et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Epidemiology of liver failure

(2011) Philippe Ichai et al.   Clinics and Research in Hepatology and Gastroenterology

Acute liver failure

(2010) William Bernal et al.   LANCET

Admission levels and early changes in serum interleukin-10 are predictive of poor outcome in acute liver failure and decompensated cirrhosis

(2010) P. A. Berry et al.   LIVER INTERNATIONAL

Toll-like Receptor 4 and Hepatic Fibrogenesis

(2010) Jean-Philippe Pradere et al.   SEMINARS IN LIVER DISEASE

Role of monocytes and macrophages in experimental and human acute liver failure

(2010) Lucia A Possamai   WORLD JOURNAL OF GASTROENTEROLOGY

Therapeutic approach to regulate innate immune response by Toll-like receptor 4 antagonist E5564 in rats with D-galactosamine-induced acute severe liver injury

(2009) Toshiyuki Kitazawa et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Salvage effect of E5564, Toll-like receptor 4 antagonist on d-galactosamine and lipopolysaccharide-induced acute liver failure in rats

(2009) Toshiyuki Kitazawa et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Bone Marrow Chimeras and c-fms Conditional Ablation (Mafia) Mice Reveal an Essential Role for Resident Myeloid Cells in Lipopolysaccharide/TLR4-Induced Corneal Inflammation

(2009) H. R. Chinnery et al.   JOURNAL OF IMMUNOLOGY

HMGB1 loves company

(2009) Marco E. Bianchi   JOURNAL OF LEUKOCYTE BIOLOGY

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

(2009) Brittany V. Martin-Murphy et al.   TOXICOLOGY LETTERS

A novel TLR4-binding peptide that inhibits LPS-induced activation of NF-κB and in vivo toxicity

(2008) Kei-ichi Sugiyama et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The importance of immune dysfunction in determining outcome in acute liver failure

(2008) Charalambos Gustav Antoniades et al.   JOURNAL OF HEPATOLOGY