The role ofATMmutations and 11q deletions in disease progression in chronic lymphocytic leukemia
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The role ofATMmutations and 11q deletions in disease progression in chronic lymphocytic leukemia
Authors
Keywords
-
Journal
LEUKEMIA & LYMPHOMA
Volume 55, Issue 6, Pages 1227-1239
Publisher
Informa UK Limited
Online
2013-08-02
DOI
10.3109/10428194.2013.829919
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin
- (2013) V. Navrkalova et al. HAEMATOLOGICA
- Clinical implications of the molecular genetics of chronic lymphocytic leukemia
- (2013) R. Foa et al. HAEMATOLOGICA
- Overview of available p53 function tests in relation toTP53andATMgene alterations and chemoresistance in chronic lymphocytic leukemia
- (2013) G. Doreen te Raa et al. LEUKEMIA & LYMPHOMA
- Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
- (2012) A. Schuh et al. BLOOD
- Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
- (2012) D. Rossi et al. BLOOD
- The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
- (2012) D. G. Oscier et al. BLOOD
- Chronic lymphocytic leukemia: A tale of one or two signals?
- (2012) Nicholas Chiorazzi et al. CELL RESEARCH
- Functional Analysis of the ATM-p53-p21 Pathway in the LRF CLL4 Trial: Blockade at the Level of p21 Is Associated with Short Response Duration
- (2012) K. Lin et al. CLINICAL CANCER RESEARCH
- ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres
- (2012) Maria Thanasoula et al. EMBO JOURNAL
- Incidence and clinical implications of ATM aberrations in chronic lymphocytic leukemia
- (2012) Peter Ouillette et al. GENES CHROMOSOMES & CANCER
- Clinical heterogeneity ofde novo11q deletion chronic lymphocytic leukaemia: prognostic relevance of extent of 11q deleted nuclei inside leukemic clone
- (2012) Roberto Marasca et al. HEMATOLOGICAL ONCOLOGY
- Biallelic ATM Inactivation Significantly Reduces Survival in Patients Treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 Trial
- (2012) Anna Skowronska et al. JOURNAL OF CLINICAL ONCOLOGY
- Trisomy 12 CLLs progress through NOTCH1 mutations
- (2012) V Balatti et al. LEUKEMIA
- Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study
- (2012) Gerard Lozanski et al. LEUKEMIA & LYMPHOMA
- The biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemia
- (2012) S N Malek ONCOGENE
- Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
- (2011) P. Ouillette et al. BLOOD
- Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL
- (2011) X. C. Badoux et al. BLOOD
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- Importance of genetics in chronic lymphocytic leukemia
- (2011) Thorsten Zenz et al. BLOOD REVIEWS
- ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression
- (2011) A. Guarini et al. HAEMATOLOGICA
- ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele
- (2011) A. Skowronska et al. HAEMATOLOGICA
- Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
- (2011) R. Gunnarsson et al. HAEMATOLOGICA
- Multivariable Model for Time to First Treatment in Patients With Chronic Lymphocytic Leukemia
- (2011) William G. Wierda et al. JOURNAL OF CLINICAL ONCOLOGY
- Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage
- (2011) B Britt-Compton et al. LEUKEMIA
- A new minimal deleted region at 11q22.3 reveals the importance of interpretation of diminished FISH signals and the choice of probe for ATM deletion screening in chronic lymphocytic leukemia
- (2011) Anne Gardiner et al. LEUKEMIA RESEARCH
- Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
- (2011) Philip M Reaper et al. Nature Chemical Biology
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clinical and diagnostic implications of monoclonal B-cell lymphocytosis
- (2010) Andy C. Rawstron et al. BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Moving from prognostic to predictive factors in chronic lymphocytic leukaemia (CLL)
- (2010) Thorsten Zenz et al. BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
- (2010) V. J. Weston et al. BLOOD
- DNA damage-induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing
- (2010) J. Mohr et al. BLOOD
- Aggressive Chronic Lymphocytic Leukemia with Elevated Genomic Complexity Is Associated with Multiple Gene Defects in the Response to DNA Double-Strand Breaks
- (2010) P. Ouillette et al. CLINICAL CANCER RESEARCH
- Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation
- (2010) D. Oscier et al. HAEMATOLOGICA
- Autophosphorylation and ATM Activation
- (2010) Sergei V. Kozlov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TP53Mutation and Survival in Chronic Lymphocytic Leukemia
- (2010) Thorsten Zenz et al. JOURNAL OF CLINICAL ONCOLOGY
- Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial
- (2010) M Hallek et al. LANCET
- ATM Activation by Oxidative Stress
- (2010) Z. Guo et al. SCIENCE
- How I treat CLL up front
- (2009) J. G. Gribben BLOOD
- Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia
- (2009) Apostolia-Maria Tsimberidou et al. CANCER
- A Novel Type of p53 Pathway Dysfunction in Chronic Lymphocytic Leukemia Resulting from Two Interacting Single Nucleotide Polymorphisms within the p21 Gene
- (2009) G. G. Johnson et al. CANCER RESEARCH
- The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness
- (2009) D. Rossi et al. CLINICAL CANCER RESEARCH
- Predictive value of 2-microglobulin ( 2-m) levels in chronic lymphocytic leukemia since Binet A stages
- (2009) M. Gentile et al. HAEMATOLOGICA
- E2F1 transcription is induced by genotoxic stress through ATM/ATR activation
- (2009) Abel L. Carcagno et al. IUBMB LIFE
- Characteristics Associated With Important Clinical End Points in Patients With Chronic Lymphocytic Leukemia at Initial Treatment
- (2009) William G. Wierda et al. JOURNAL OF CLINICAL ONCOLOGY
- Subcutaneous Alemtuzumab in Fludarabine-Refractory Chronic Lymphocytic Leukemia: Clinical Results and Prognostic Marker Analyses From the CLL2H Study of the German Chronic Lymphocytic Leukemia Study Group
- (2009) Stephan Stilgenbauer et al. JOURNAL OF CLINICAL ONCOLOGY
- Atypical 11q deletions identified by array CGH may be missed by FISH panels for prognostic markers in chronic lymphocytic leukemia
- (2009) S R Gunn et al. LEUKEMIA
- CtIP Links DNA Double-Strand Break Sensing to Resection
- (2009) Zhongsheng You et al. MOLECULAR CELL
- Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia
- (2008) L. Kujawski et al. BLOOD
- Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
- (2008) A. Ferrajoli et al. BLOOD
- Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up
- (2008) T. Zenz et al. BLOOD
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- New prognostic markers in chronic lymphocytic leukemia
- (2008) Carol Moreno et al. BLOOD REVIEWS
- Genetic Variants in Apoptosis and Immunoregulation-Related Genes Are Associated with Risk of Chronic Lymphocytic Leukemia
- (2008) A. Enjuanes et al. CANCER RESEARCH
- Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair
- (2008) R. Scott Williams et al. CELL
- The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
- (2008) F Dicker et al. LEUKEMIA
- A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL
- (2008) O G Best et al. LEUKEMIA
- A Novel Tel1/ATM N-Terminal Motif, TAN, Is Essential for Telomere Length Maintenance and a DNA Damage Response
- (2008) J. J. Seidel et al. MOLECULAR AND CELLULAR BIOLOGY
- ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
- (2008) Aaron A. Goodarzi et al. MOLECULAR CELL
- -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
- (2008) A. Kinner et al. NUCLEIC ACIDS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started