ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

(2011) Luis I Toledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

p53 Prevents Entry into Mitosis with Uncapped Telomeres

(2010) Maria Thanasoula et al.   CURRENT BIOLOGY

TPP1 Is Required for TERT Recruitment, Telomere Elongation during Nuclear Reprogramming, and Normal Skin Development in Mice

(2010) Agueda M. Tejera et al.   DEVELOPMENTAL CELL

Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase

(2010) Halfdan Beck et al.   JOURNAL OF CELL BIOLOGY

MiR-322/424 and -503 Are Induced during Muscle Differentiation and Promote Cell Cycle Quiescence and Differentiation by Down-Regulation of Cdc25A

(2010) Sukumar Sarkar et al.   MOLECULAR BIOLOGY OF THE CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation

(2009) Sophie Badie et al.   JOURNAL OF CELL BIOLOGY

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint

(2009) Marina Melixetian et al.   NATURE CELL BIOLOGY

Differential Roles for Checkpoint Kinases in DNA Damage-dependent Degradation of the Cdc25A Protein Phosphatase

(2008) Jianping Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Dissection of Human and Mouse POT1 Proteins

(2008) W. Palm et al.   MOLECULAR AND CELLULAR BIOLOGY