Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4
Authors
Keywords
-
Journal
LEUKEMIA
Volume 26, Issue 1, Pages 34-53
Publisher
Springer Nature
Online
2011-09-02
DOI
10.1038/leu.2011.197
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Crosstalk between CXCR4/Stromal Derived Factor-1 and VLA-4/VCAM-1 Pathways Regulates Neutrophil Retention in the Bone Marrow
- (2014) J. M. Petty et al. JOURNAL OF IMMUNOLOGY
- Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches
- (2011) Stephanie Smith-Berdan et al. Cell Stem Cell
- The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
- (2011) Armin Ehninger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice
- (2011) Matthew J. Christopher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
- (2011) Andrew Chow et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cooperation of β2- and β3-adrenergic receptors in hematopoietic progenitor cell mobilization
- (2010) Simón Méndez-Ferrer et al. Annals of the New York Academy of Sciences
- Comparison of Unmobilized and Mobilized Graft Characteristics and the Implications of Cell Subsets on Autologous and Allogeneic Transplantation Outcomes
- (2010) Stefan Fruehauf et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo
- (2010) S. Lymperi et al. BLOOD
- Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
- (2010) I. G. Winkler et al. BLOOD
- CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function
- (2010) D Jing et al. BONE MARROW TRANSPLANTATION
- A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II study
- (2010) Stefan Fruehauf et al. CYTOTHERAPY
- Essential roles of VLA-4 in the hematopoietic system
- (2010) Yoichi Imai et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- S1P1 receptor directs the release of immature B cells from bone marrow into blood
- (2010) Maria L. Allende et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication
- (2010) Renato T. Skerlj et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex
- (2010) M Z Ratajczak et al. LEUKEMIA
- Endothelial precursors in vascular repair
- (2010) John Paul Kirton et al. MICROVASCULAR RESEARCH
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
- (2010) Ulrike Naumann et al. PLoS One
- CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction
- (2010) K. Jujo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Can inhibition of the SDF-1/CXCR4 axis eradicate acute leukemia?
- (2010) Sigal Tavor et al. SEMINARS IN CANCER BIOLOGY
- Review: Anti-adhesion molecule therapy for inflammatory bowel disease
- (2010) Subrata Ghosh et al. Therapeutic Advances in Gastroenterology
- The Novel CXCR4 Antagonist KRH-3955 Is an Orally Bioavailable and Extremely Potent Inhibitor of Human Immunodeficiency Virus Type 1 Infection: Comparative Studies with AMD3100
- (2009) T. Murakami et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Blockade of X4-Tropic HIV-1 Cellular Entry by GSK812397, a Potent Noncompetitive CXCR4 Receptor Antagonist
- (2009) S. Jenkinson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Integrins during evolution: Evolutionary trees and model organisms
- (2009) Mark S. Johnson et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Successful Stem Cell Remobilization Using Plerixafor (Mozobil) Plus Granulocyte Colony-Stimulating Factor in Patients with Non-Hodgkin Lymphoma: Results from the Plerixafor NHL Phase 3 Study Rescue Protocol
- (2009) Ivana N. Micallef et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Treatment with Plerixafor in non-Hodgkin's Lymphoma and Multiple Myeloma Patients to Increase the Number of Peripheral Blood Stem Cells When Given a Mobilizing Regimen of G-CSF: Implications for the Heavily Pretreated Patient
- (2009) Patrick Stiff et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma
- (2009) Douglas A. Stewart et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells
- (2009) P. Ramirez et al. BLOOD
- Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34+ cell populations based on global gene and microRNA expression signatures
- (2009) R. E. Donahue et al. BLOOD
- Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization
- (2009) M. J. Christopher et al. BLOOD
- The leukemic stem cell niche: current concepts and therapeutic opportunities
- (2009) S. W. Lane et al. BLOOD
- Improving stem cell mobilization strategies: future directions
- (2009) W Bensinger et al. BONE MARROW TRANSPLANTATION
- The CXCL12-3′A allele is associated with a higher mobilization yield of CD34 progenitors to the peripheral blood of healthy donors for allogeneic transplantation
- (2009) K Bogunia-Kubik et al. BONE MARROW TRANSPLANTATION
- Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: an open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization
- (2009) M J Dugan et al. BONE MARROW TRANSPLANTATION
- Rescue from failed growth factor and/or chemotherapy HSC mobilization with G-CSF and plerixafor (AMD3100): an institutional experience
- (2009) C J Fowler et al. BONE MARROW TRANSPLANTATION
- Integrins
- (2009) Malgorzata Barczyk et al. CELL AND TISSUE RESEARCH
- Differential Mobilization of Subsets of Progenitor Cells from the Bone Marrow
- (2009) Simon C. Pitchford et al. Cell Stem Cell
- Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4‐Tropic HIV Type 1
- (2009) Graeme Moyle et al. CLINICAL INFECTIOUS DISEASES
- Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
- (2009) S. G. Sayyed et al. DIABETOLOGIA
- S1066 Oral Alpha-4 Integrin Inhibitor (AJM300) in Patients with Active Crohn's Disease — A Randomized, Double-Blind, Placebo-Controlled Trial
- (2009) Masakazu Takazoe et al. GASTROENTEROLOGY
- Linking integrin conformation to function
- (2009) J. A. Askari et al. JOURNAL OF CELL SCIENCE
- Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma
- (2009) John F. DiPersio et al. JOURNAL OF CLINICAL ONCOLOGY
- Discovery oftrans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid: An Orally Active, Selective Very Late Antigen-4 Antagonist
- (2009) Fumihito Muro et al. JOURNAL OF MEDICINAL CHEMISTRY
- First Results for Agents Targeting Cancer-Related Inflammation
- (2009) Ken Garber JNCI-Journal of the National Cancer Institute
- The CXCR4 antagonist 4F-benzoyl-TN14003 stimulates the recovery of the bone marrow after transplantation
- (2009) M Abraham et al. LEUKEMIA
- Concurrent Blockade of α4-Integrin and CXCR4 in Hematopoietic Stem/Progenitor Cell Mobilization
- (2009) Halvard Bonig et al. STEM CELLS
- Impact of Mobilization and Remobilization Strategies on Achieving Sufficient Stem Cell Yields for Autologous Transplantation
- (2008) Iskra Pusic et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma
- (2008) Amanda Cashen et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction
- (2008) S. M. Devine et al. BLOOD
- The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases
- (2008) I. L. Weissman et al. BLOOD
- The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans
- (2008) F. Zohren et al. BLOOD
- Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab
- (2008) H. Bonig et al. BLOOD
- Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
- (2008) Z. Zeng et al. BLOOD
- Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
- (2008) B. Nervi et al. BLOOD
- Control of Chemokine-Guided Cell Migration by Ligand Sequestration
- (2008) Bijan Boldajipour et al. CELL
- Peripheral blood stem cell mobilization: new regimens, new cells, where do we stand
- (2008) Louis M Pelus CURRENT OPINION IN HEMATOLOGY
- The design, structures and therapeutic potential of protein epitope mimetics
- (2008) John A. Robinson et al. DRUG DISCOVERY TODAY
- Very small embryonic-like stem cells: Characterization, developmental origin, and biological significance
- (2008) Mariusz Z. Ratajczak et al. EXPERIMENTAL HEMATOLOGY
- Secreted Trefoil Factor 2 Activates the CXCR4 Receptor in Epithelial and Lymphocytic Cancer Cell Lines
- (2008) Zinaida Dubeykovskaya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CXCR4 is required for the quiescence of primitive hematopoietic cells
- (2008) Yuchun Nie et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
- (2008) Tanja Nicole Hartmann et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Blocking α4-integrins — A small molecule approach to treatment of multiple sclerosis
- (2008) Richard J. Davenport et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis
- (2008) Ping Jin et al. Journal of Translational Medicine
- CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
- (2008) J A Burger et al. LEUKEMIA
- Anti-HIV Activity and Resistance Profile of the CXC Chemokine Receptor 4 Antagonist POL3026
- (2008) G. Moncunill et al. MOLECULAR PHARMACOLOGY
- Haematopoietic stem cell release is regulated by circadian oscillations
- (2008) Simón Méndez-Ferrer et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started