Article
Nanoscience & Nanotechnology
Jihyuk Yang, Mojun Chen, Heekwon Lee, Zhaoyi Xu, Zhiwen Zhou, Shien-Ping Feng, Ji Tae Kim
Summary: Peptide-based materials are being used as smart building blocks for nanobiodevices due to their programmable properties, with recent advancements allowing for the fabrication of freeform, crystalline peptide structures using a combination of meniscus-guided 3D printing and molecular self-assembly. This approach enables layer-by-layer, crystalline 3D printing with high spatial resolution and the potential for piezoelectric behavior, suggesting promising applications in bioelectronic devices.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Hironaga Noguchi, Yoshiki Nakamura, Sayaka Tezuka, Takakazu Seki, Kazuki Yatsu, Takuma Narimatsu, Yasuaki Nakata, Yuhei Hayamizu
Summary: Biosensors with two-dimensional materials have gained wide interest due to their high sensitivity. Among them, single-layer MoS2 has become a new class of biosensing platform owing to its semiconducting property. Immobilization of bioprobes directly onto the MoS2 surface with chemical bonding or random physisorption has been widely studied. However, these approaches potentially cause a reduction of conductivity and sensitivity of the biosensor.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Ji Hoon Kim, Ji Min Kim, Gil Won Lee, Gyu Hyeon Shim, Sun Taek Lim, Koung Moon Kim, Thi To Nguyen Vo, Boyeon Kweon, Somchai Wongwises, Dong Wook Jerng, Moo Hwan Kim, Ho Seon Ahn
Summary: Researchers have developed a simple method for the formation of large-scale 3D graphene networks, with the structural morphology of the network being modifiable by controlling vaporization rate, surface temperature of the target substrate, and amount of discharged colloids. The self-assembled graphene possesses excellent electrical and mechanical properties, making it suitable for mass production of graphene-based materials.
Article
Chemistry, Multidisciplinary
Wei Kang, Xiao Ma, Deepika Kakarla, Huawei Zhang, Yunming Fang, Baizhu Chen, Kongfu Zhu, Danni Zheng, Zhiyue Wu, Bo Li, Chuang Xue
Summary: Cells use self-assembled biomaterials to coordinate reactions, but mimicking such spatial organization in engineered systems is challenging. This study demonstrates that protein cages can enhance cascade reactions by organizing enzymes, leading to increased productivity. This versatile system offers a powerful tool for enzyme spatial organization in biocatalysis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Baoyu Yang, Fan Liu, Yanxia Liu, Jiayu Dong, Muhao Liu, Shuang Wang, Lan Zhang
Summary: Silicon-based anode materials for lithium batteries face significant challenges with regard to structural instability and insufficient electron/ion conductivity. In this study, a three-dimensional silicon/carbon framework (CHSP) is proposed to address these issues. By effectively fixing nano-Si particles in an interconnected porous conducting network, the CHSP material enhances ion/electron transport and buffers the volume change of silicon. The resulting CHSP demonstrates satisfactory rate performance and high reversible capacity, making it a promising approach to improve the performance of silicon anodes.
JOURNAL OF POWER SOURCES
(2023)
Article
Biotechnology & Applied Microbiology
Elena Johanna Weigl, Salih Demir, Tanja Schmid, Alina Hotes, Oliver Muensterer, Roland Kappler
Summary: This study established a reliable 3D testing platform for hepatoblastoma (HB) using liver-derived scaffolds and HB cell lines. The newly generated biological scaffolds consisted of liver-specific extracellular matrix components, and the cultivation of HB cell lines on these scaffolds led to the formation of 3D tumor structures. Analyses showed reliable reproducibility of drug response in HB models.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Yiyuan Shi, Sisi Li, Zhimiao Tian, Xiansen Yang, Yubing Dong, Yaofeng Zhu, Yaqin Fu
Summary: The study prepared 3D hierarchically porous Ti3C2Tx MXene@polyaniline hybrids via self-assembly process, showing excellent microwave absorption performance and providing an efficient design strategy for microwave absorption.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Tsuyoshi Mashima, Bas J. H. M. Rosier, Koji Oohora, Tom F. A. de Greef, Takashi Hayashi, Luc Brunsveld
Summary: Hexameric hemoprotein (HTHP) is used as a scaffold protein for the assembly and activation of the apoptotic signalling enzyme caspase-9, employing short DNA elements for modular recruitment domains. This allows for advanced control over protein assembly and activity state.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Aaron Michelson, Honghu Zhang, Shuting Xiang, Oleg Gang
Summary: This study demonstrates a method for creating nanoengineered 3D SiC architectures using DNA-based self-assembly and templating processes, resulting in highly structured and spatially prescribed SiC nanoarchitectures with significant enhancements in electrical conductivity.
Article
Chemistry, Multidisciplinary
Hee Uk Lee, Ho Yeon Lee, Joon-Hyung Jin, Bong Geun Chung
Summary: This study developed a wireless rechargeable supercapacitor by integrating a commercial wireless charger and charging receptor with three-dimensional printed supercapacitors. A cost-effective 3D-printed supercapacitor was fabricated using a polylactic acid-based plastic substrate and MnO2 and V2O5 composite inks. The addition of poly(3,4-ethylenedioxythiophene)@graphene flake enhanced the electrical conductivity and catalytic activity of the supercapacitor. The results showed high specific capacitance, energy density, and cycling stability. The effect of electrolyte cations on the electrochemical performance was also investigated.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Samiran Morang, Ashutosh Bandyopadhyay, Jay Hind Rajput, Biman B. Mandal, Atharva Poundarik, Niranjan Karak
Summary: Waterborne polyurethanes with smart attributes like self-healing, shape-memory, reprocessability, and excellent mechanical properties are achieved through the triple synergistic effect of dynamic hard domains, asymmetric IPDI-IPDA architecture, and shape memory effect. This strategy leads to the synthesis of robust self-healable WPUs with high healing efficiency, shape recovery, and outstanding mechanical strength. The SHWPU elastomer exhibits all characteristics of advanced materials with smart attributes and eco-friendly nature.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Multidisciplinary Sciences
Pawel W. Majewski, Aaron Michelson, Marco A. L. Cordeiro, Cheng Tian, Chunli Ma, Kim Kisslinger, Ye Tian, Wenyan Liu, Eric A. Stach, Kevin G. Yager, Oleg Gang
Summary: The rapid development of DNA-based assembly methods allows for the creation of organized nanomaterials with versatile capabilities. By creating inorganic, silica-based replicas of 3D periodic DNA-NP structures, the formed nanomaterials demonstrate excellent resiliency and stability under extreme conditions. This approach opens up new possibilities for the use of DNA assembly strategies in creating organized nanomaterials for a broad range of operational conditions.
Article
Chemistry, Multidisciplinary
Ulyana Shimanovich, Aviad Levin, Dror Eliaz, Thomas Michaels, Zenon Toprakcioglu, Birgitto Frohm, Erwin De Genst, Sara Linsey, Karin S. Akerfeldt, Tuomas P. J. Knowles
Summary: Peptides and proteins can self-assemble into supramolecular entities through non-covalent interactions, providing the functional basis of life. Environmental conditions, such as pH, can modulate these assembly processes, inspiring the development of responsive functional materials based on peptide building blocks. The stimuli-responsive assembly of amyloidogenic peptide can be used to create environmentally responsive microcapsules for controlled release of biomolecules like antibodies.
Article
Nanoscience & Nanotechnology
Joshy Joseph, Sajena K. Saraswathi
Summary: This study reports the hydrogen-bonding-directed self-assembly of AIE-active TPE chromophores into one-dimensional fibers and hierarchical organogels, and demonstrates the control of their properties through the molecular recognition property of thymine nucleobase.
ACS APPLIED NANO MATERIALS
(2022)
Article
Multidisciplinary Sciences
Kunhao Yu, Zhangzhengrong Feng, Haixu Du, An Xin, Kyung Hoon Lee, Ketian Li, Yipin Su, Qiming Wang, Nicholas X. Fang, Chiara Daraio
Summary: The study achieved hybrid materials that use photosynthesis of embedded chloroplasts to remodel microstructures, enhancing mechanical properties and enabling 3D printing of functional structures. The remodeling behavior can be suspended by freezing chloroplasts, regulated by mechanical preloads, and reversed by environmental cues.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Electrochemistry
Leonardo Ciogli, Rosaceleste Zumpano, Andrey A. Poloznikov, Dmitry M. Hushpulian, Vladimir I. Tishkov, Rafael Andreu, Lo Gorton, Franco Mazzei, Gabriele Favero, Paolo Bollella
Summary: A novel electrode platform for H2O2 detection was developed by immobilizing r-TOP on p-PD/MWCNTs/G modified graphite electrodes, enhancing sensitivity, stability, and selectivity while preventing enzyme inactivation due to the electro-Fenton reaction. The electrode exhibited a lower limit of detection of 1.8 mu M H2O2, an extended linear range between 6 and 900 mu M H2O2, and increased sensitivity compared to previous work based on TOP.
Article
Biochemical Research Methods
Rosaceleste Zumpano, Manuela Manghisi, Francesca Polli, Cristine D'Agostino, Federica Ietto, Gabriele Favero, Franco Mazzei
Summary: This study developed a label-free electrochemical immunosensor for the quick, cheap, and straightforward determination of atrazine, achieving detection through a technological platform and specific treatment methods. Under optimal experimental conditions, the immunosensor exhibited good linearity range, limit of detection, reproducibility, and stability, making it suitable for successful application in the detection and monitoring of atrazine in real water samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Polymer Science
Valeria Gabrielli, Roberto Baretta, Roberto Pilot, Alberta Ferrarini, Marco Frasconi
Summary: Metal-coordination complexes are used as supramolecular cross-linkers to develop hydrogels with tunable and dynamic mechanical properties. However, the understanding of the mechanism behind the structure and properties of these hydrogels is limited. This study combines NMR spectroscopy and MD simulations to investigate the formation of cellulose-based hydrogels induced by metal-ligand interactions. The results uncover the coordination network between the metal center and polymer chain, and reveal the structuration of water and different orientations of the chains within the hydrogel. This understanding will advance the exploitation of metal-coordinated hydrogels for various biomedical applications.
Article
Chemistry, Multidisciplinary
V. Gabrielli, E. Missale, M. Cattelan, M. F. Pantano, M. Frasconi
Summary: Cellulose nanocrystal (CNC) is a promising building block for the assembly of lightweight renewable materials. This article demonstrates how the assembly and mechanical properties of cellulose thin films can be controlled by manipulating the interfacial interactions of cellulose nanocrystals.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Roberto Baretta, Valeria Gabrielli, Marco Frasconi
Summary: This study presents an efficient one-pot method for preparing an enzyme-nanozyme hydrogel composite. The composite not only exhibits peroxidase-like activity but also demonstrates enhanced cascade catalytic performance due to the proximity effect of the enzyme-nanozyme system. Compared to enzyme mixture in solution, the composite hydrogel shows improved glucose detection and stability. The developed colorimetric assay has the potential for clinical diagnosis.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Physical
B. Kalinic, L. Girardi, P. Ragonese, A. Faramawy, G. Mattei, M. Frasconi, R. Baretta, S. Bogialli, M. Roverso, G. A. Rizzi, C. Maurizio
Summary: This study sheds new light on the formation mechanism of Co3O4 nanopetals on Si-based photoanodes and their applications in the rapid chemisorption, photoelectrochemical detection, and removal of fenitrothion (FNT). The nanopetals exhibit high photoelectrocatalytic activity due to their increased active area. Under visible light, the nanostructured film efficiently removes the pesticide in water through direct coordination.
APPLIED SURFACE SCIENCE
(2022)
Review
Chemistry, Analytical
Valeria Gabrielli, Marco Frasconi
Summary: This review discusses the application of cellulose as a sensor material, introduces the properties and functionalization methods of cellulose derivatives, and explores the recent advances of cellulose-based functional materials in optical and electrochemical sensors for biomedical and environmental monitoring.
Article
Chemistry, Analytical
Roberto Baretta, Ada Raucci, Stefano Cinti, Marco Frasconi
Summary: Hydrogels are promising porous soft materials for biosensing platforms due to their versatility and ability to immobilize enzymes and nanomaterials. However, stable hydrogel films integrating catalytic nanomaterials and enzymes on electrode surfaces are necessary for electrochemical biosensors. In this study, hydrogel films embedding Prussian Blue nanoparticles and enzymes were prepared using a one-pot synthesis method. The resulting hydrogel composites showed high electrocatalytic activity and were used to fabricate amperometric biosensors for the rapid detection of glucose and ethanol in serum. This approach holds great promise for the development of portable electrochemical sensors for various analytes.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Francesca Polli, Cristine D'Agostino, Rosaceleste Zumpano, Viviana De Martino, Gabriele Favero, Luciano Colangelo, Salvatore Minisola, Franco Mazzei
Summary: We report a new sensitive label-free electrochemical immunosensor that can accurately detect Vitamin D-3 in untreated serum samples. The immunosensor showed high sensitivity and a wide linear range, and showed good agreement with the reference method, suggesting its potential use for rapid monitoring of low Vitamin D levels.
Article
Chemistry, Multidisciplinary
M. F. Pantano, E. Missale, L. Gazzato, R. Pilot, F. Sedona, G. Speranza, M. Frasconi
Summary: In this study, a method for synthesizing, transferring, and mechanically characterizing large-area freestanding 2D COF films is reported. The developed method enables the direct transfer of COF nanofilms onto patterned substrates for mechanical characterization. The experimental results demonstrate the high stiffness and strength of COF nanofilms, making them suitable for applications that require high mechanical performance. The study also provides a foundation for understanding the relationship between the structures and macroscopic mechanical properties of 2D COFs.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yanchao Lyu, Lucia Morillas Becerril, Mirko Vanzan, Stefano Corni, Mattia Cattelan, Gaetano Granozzi, Marco Frasconi, Piu Rajak, Pritam Banerjee, Regina Ciancio, Fabrizio Mancin, Paolo Scrimin
Summary: Understanding the interaction between amines and gold nanoparticles is crucial for stabilizing nanosystems, forming protein corona, and preparing semi-synthetic nanozymes. Various techniques, including fluorescence spectroscopy and molecular simulation, are used to investigate these interactions. The results reveal that amines interact with surface Au(0) atoms of the nanoparticles through their lone electron pair in a manner correlated with their basicity. The kinetics and mode of binding depend on the position of gold atoms and can involve either a single or two Au(0) atoms with nitrogen.
ADVANCED MATERIALS
(2023)
Article
Biochemical Research Methods
Andrea Calcaterra, Francesca Polli, Lara Lamelza, Cristina Del Plato, Silvia Cammarone, Francesca Ghirga, Bruno Botta, Franco Mazzei, Deborah Quaglio
Summary: Recent efforts have focused on the development of selective, sensitive, fast response, and miniaturized immunosensors for analyte monitoring. However, the complexity of immobilizing antibodies to the sensor surface remains a challenge. Supramolecular chemistry has emerged as a suitable tool to preorganize artificial receptors and improve the properties of self-assembled monolayers, enabling the development of sensitive label-free electrochemical immunosensors.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Francesca Polli, Gabriele Cianfoni, Rem Elnahas, Laura Mangiardi, Francesca A. Scaramuzzo, Silvia Cammarone, Deborah Quaglio, Andrea Calcaterra, Marco Pierini, Franco Mazzei, Robertino Zanoni, Bruno Botta, Francesca Ghirga
Summary: A practical supramolecular Ab conjugation strategy based on resorc[4]arene modifiers was developed to immobilize antibodies onto the surface of carbon nanotubes (CNTs) for selective binding to target antigens (Ags). The study utilized host-guest approach and synthesized resorc[4]arene linkers R1 and R2 to improve the orientation of antibodies on CNTs and optimize the Ab/Ag interaction, showing potential applicability in label-free immunosensor development.
Article
Biochemistry & Molecular Biology
Cristine D'Agostino, Claudia Chillocci, Francesca Polli, Luca Surace, Federica Simonetti, Marco Agostini, Sergio Brutti, Franco Mazzei, Gabriele Favero, Rosaceleste Zumpano
Summary: This study aimed to develop a user-friendly smartphone-based electrochemical biosensor for the rapid assessment of total polyphenols content in coffee blends. The biosensor, based on modified carbon-based screen-printed electrode, demonstrated high sensitivity and a wide linear range, and was validated for quantifying polyphenols in coffee blends.
Article
Electrochemistry
Juan Pinuela-Noval, Daniel Fernandez-Gonzalez, Sergio Brutti, Marta Suarez, Franco Mazzei, Maria Assunta Navarra, Luis Felipe Verdeja, Adolfo Fernandez, Marco Agostini
Summary: This study proposes for the first time the use of molybdenum and chromium carbides as additives to stabilize graphite/silicon composites. Spark plasma sintering technology is utilized to sinter the electrode powders. It is demonstrated that the presence of molybdenum or chromium carbides enhances the performance of C/Si electrodes, improving the cycling stability in lithium cells.