Journal
LANGMUIR
Volume 27, Issue 19, Pages 11767-11772Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la202640a
Keywords
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Funding
- Liquid Crystal Materials Research Center (NSF MRSEC) [DMR-0455490]
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [0820579] Funding Source: National Science Foundation
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Nematic liquid crystals (LC) were exposed to isolated DNA molecules extended on a surface that imparted a negligible influence on the LC orientation. Although single-stranded DNA aligned the LC in the extension direction, double-stranded DNA (dsDNA) caused alignment at an oblique angle, providing a characteristic response to the chiral dsDNA helix that was readily observed optically. The intrinsic amplification due to LC orientational correlations enabled a macroscopic visible response to a single molecule of extended dsDNA.
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