Modulation of excitatory neurotransmission by neuronal/glial signalling molecules: interplay between purinergic and glutamatergic systems

Chronic Caffeine Consumption Prevents Memory Disturbance in Different Animal Models of Memory Decline

(2017) Rodrigo A. Cunha et al.   JOURNAL OF ALZHEIMERS DISEASE

Allosteric mechanisms within the adenosine A2A–dopamine D2 receptor heterotetramer

(2016) Sergi Ferré et al.   NEUROPHARMACOLOGY

Purinergic neurone-glia signalling in cognitive-related pathologies

(2016) Peter Illes et al.   NEUROPHARMACOLOGY

An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration

(2016) Geoffrey Burnstock   NEUROPHARMACOLOGY

Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation

(2015) Ana M. Sebastião et al.   BRAIN RESEARCH

Allosteric modulators of NMDA receptors: multiple sites and mechanisms

(2015) Shujia Zhu et al.   CURRENT OPINION IN PHARMACOLOGY

Adenosine A2Areceptors permit mGluR5-evoked tyrosine phosphorylation of NR2B (Tyr1472) in rat hippocampus: a possible key mechanism in NMDA receptor modulation

(2015) Konstantinos Sarantis et al.   JOURNAL OF NEUROCHEMISTRY

Inactivation of adenosine A 2A receptors reverses working memory deficits at early stages of Huntington's disease models

(2015) Wei Li et al.   NEUROBIOLOGY OF DISEASE

Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a

(2015) Tsvetan Serchov et al.   NEURON

Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons

(2015) In-Sun Choi et al.   NEUROPHARMACOLOGY

Caffeine acts through neuronal adenosine A2Areceptors to prevent mood and memory dysfunction triggered by chronic stress

(2015) Manuella P. Kaster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP as a multi-target danger signal in the brain

(2015) Ricardo J. Rodrigues et al.   Frontiers in Neuroscience

Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review

(2015) Nicolas D. Iadarola et al.   Therapeutic Advances in Chronic Disease

Gliotransmission: focus on exocytotic release of L-glutamate and D-serine from astrocytes

(2015) Magalie Martineau   BIOCHEMICAL SOCIETY TRANSACTIONS

Adenosine A2A-D2 Receptor-Receptor Interactions in Putative Heteromers in the Regulation of the Striato-Pallidal GABA Pathway: Possible Relevance for Parkinson’s Disease and its Treatment

(2014) Sarah Beggiato et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Activation of α1-adrenoceptors enhances excitatory synaptic transmission via a pre- and postsynaptic protein kinase C-dependent mechanism in the medial prefrontal cortex of rats

(2014) Fei Luo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species

(2014) Christoph Ficker et al.   GLIA

Phenylephrine enhances glutamate release in the medial prefrontal cortex through interaction with N-type Ca2+channels and release machinery

(2014) Fei Luo et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of Ser1166 on GluN2B by PKA Is Critical to Synaptic NMDA Receptor Function and Ca 2+ Signaling in Spines

(2014) Jessica A. Murphy et al.   JOURNAL OF NEUROSCIENCE

Activation of Neuronal NMDA Receptors Triggers Transient ATP-Mediated Microglial Process Outgrowth

(2014) L. Dissing-Olesen et al.   JOURNAL OF NEUROSCIENCE

Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases: A review

(2014) Marla Rivera-Oliver et al.   LIFE SCIENCES

Modulation of the NMDA Receptor Through Secreted Soluble Factors

(2014) Waldo Cerpa et al.   MOLECULAR NEUROBIOLOGY

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons

(2014) Johan-Till Pougnet et al.   NEURON

Looks Can Be Deceiving: Reconsidering the Evidence for Gliotransmission

(2014) Steven A. Sloan et al.   NEURON

Slow Neuromodulation Mediated by ATP P2X Receptors

(2014) Ji Xu et al.   NEURON

Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens

(2014) Alessia Salamone et al.   NEUROPHARMACOLOGY

Impaired Cognition after Stimulation of P2Y1 Receptors in the Rat Medial Prefrontal Cortex

(2014) Holger Koch et al.   NEUROPSYCHOPHARMACOLOGY

Dopamine Preferentially Inhibits NMDA Receptor-Mediated EPSCs by Acting on Presynaptic D1 Receptors in Nucleus Accumbens during Postnatal Development

(2014) Liming Zhang et al.   PLoS One

P2X7 receptor: an emerging target in central nervous system diseases

(2014) Beáta Sperlágh et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbens

(2014) Stefania Zappettini et al.   Frontiers in Cellular Neuroscience

Neuron-glia networks: integral gear of brain function

(2014) Gertrudis Perea et al.   Frontiers in Cellular Neuroscience

The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity

(2014) Thomas E. Chater et al.   Frontiers in Cellular Neuroscience

CaMKII-dependent phosphorylation of GluK5 mediates plasticity of kainate receptors

(2013) Mario Carta et al.   EMBO JOURNAL

Microglia release ATP by exocytosis

(2013) Yoshio Imura et al.   GLIA

Astrocyte-derived ATP modulates depressive-like behaviors

(2013) Xiong Cao et al.   NATURE MEDICINE

Cornichon Proteins Determine the Subunit Composition of Synaptic AMPA Receptors

(2013) Bruce E. Herring et al.   NEURON

Kainate Receptors in Health and Disease

(2013) Juan Lerma et al.   NEURON

Nucleotide signaling in astrogliosis

(2013) Heike Franke et al.   NEUROSCIENCE LETTERS

Regulation of Dopamine D1 Receptor Dynamics within the Postsynaptic Density of Hippocampal Glutamate Synapses

(2013) Laurent Ladepeche et al.   PLoS One

Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors

(2013) L. Ladepeche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine: setting the stage for plasticity

(2013) Raquel B. Dias et al.   TRENDS IN NEUROSCIENCES

GluN2A versus GluN2B: twins, but quite different

(2013) Xiao-Min Zhang et al.   Neuroscience Bulletin

Mechanisms of glycine release, which build up synaptic and extrasynaptic glycine levels: The role of synaptic and non-synaptic glycine transporters

(2012) Laszlo G. Harsing et al.   BRAIN RESEARCH BULLETIN

Activation of extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1 neurons

(2012) Dan-dan Liu et al.   BRAIN RESEARCH BULLETIN

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Synaptic plasticity of NMDA receptors: mechanisms and functional implications

(2012) David L Hunt et al.   CURRENT OPINION IN NEUROBIOLOGY

Heterosynaptic long-term depression mediated by ATP released from astrocytes

(2012) Jiadong Chen et al.   GLIA

The “quad-partite” synapse: Microglia-synapse interactions in the developing and mature CNS

(2012) Dorothy P. Schafer et al.   GLIA

Artifact versus reality-How astrocytes contribute to synaptic events

(2012) Maiken Nedergaard et al.   GLIA

Synaptic NMDA Receptors Mediate Hypoxic Excitotoxic Death

(2012) C. M. Wroge et al.   JOURNAL OF NEUROSCIENCE

Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators

(2012) Daniel T. Monaghan et al.   NEUROCHEMISTRY INTERNATIONAL

Neuromodulation by Extracellular ATP and P2X Receptors in the CNS

(2012) Baljit S. Khakh et al.   NEURON

Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus

(2012) Motoki Tanaka et al.   NEUROPHARMACOLOGY

The NMDA receptor as a target for cognitive enhancement

(2012) Graham L. Collingridge et al.   NEUROPHARMACOLOGY

Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity

(2012) D. Lovatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role for purinergic receptors in memory processing in young chicks

(2011) Catherine Cronin et al.   BEHAVIOURAL BRAIN RESEARCH

The regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits

(2011) Christoph Straub et al.   CURRENT OPINION IN NEUROBIOLOGY

The Role of Extracellular Adenosine in Chemical Neurotransmission in the Hippocampus and Basal Ganglia: Pharmacological and Clinical Aspects

(2011) Beata Sperlagh et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Adenosine and ATP Receptors in the Brain

(2011) Geoffrey Burnstock et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases

(2011) Kai Yang et al.   EMBO JOURNAL

Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons

(2011) Andrew W. Baxter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing

(2011) Ana R. Costenla et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway

(2011) Qiudong Deng et al.   GLIA

Synaptic Targeting and Functional Modulation of GluK1 Kainate Receptors by the Auxiliary Neuropilin and Tolloid-Like (NETO) Proteins

(2011) B. A. Copits et al.   JOURNAL OF NEUROSCIENCE

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

(2011) Rita Z. Goldstein et al.   NATURE REVIEWS NEUROSCIENCE

Purinergic modulation of the excitatory synaptic input onto rat striatal neurons

(2011) Michael Tautenhahn et al.   NEUROPHARMACOLOGY

Chronic caffeine consumption prevents cognitive decline from young to middle age in rats, and is associated with increased length, branching, and spine density of basal dendrites in CA1 hippocampal neurons

(2011) S. Vila-Luna et al.   NEUROSCIENCE

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purinergic signalling: From normal behaviour to pathological brain function

(2011) Geoffrey Burnstock et al.   PROGRESS IN NEUROBIOLOGY

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

ATP: A ubiquitous gliotransmitter integrating neuron–glial networks

(2011) Arthur M. Butt   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Neurosteroid modulation of N-methyl-d-aspartate receptors: Molecular mechanism and behavioral effects

(2011) Miloslav Korinek et al.   STEROIDS

Adenosine receptors and brain diseases: Neuroprotection and neurodegeneration

(2010) Catarina V. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Rodent Cortical Astroglia Express In Situ Functional P2X7 Receptors Sensing Pathologically High ATP Concentrations

(2010) João Filipe Oliveira et al.   CEREBRAL CORTEX

Enhancement of AMPA currents and GluR1 membrane expression through PKA-coupled adenosine A2A receptors

(2010) Raquel B. Dias et al.   HIPPOCAMPUS

The Muscarinic Long-Term Enhancement of NMDA and AMPA Receptor-Mediated Transmission at Schaffer Collateral Synapses Develop through Different Intracellular Mechanisms

(2010) D. F. de Sevilla et al.   JOURNAL OF NEUROSCIENCE

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95

(2010) Jihoon Jo et al.   NATURE NEUROSCIENCE

Hippocampal AMPA Receptor Gating Controlled by Both TARP and Cornichon Proteins

(2010) Akihiko S. Kato et al.   NEURON

Casein Kinase 2 Regulates the NR2 Subunit Composition of Synaptic NMDA Receptors

(2010) Antonio Sanz-Clemente et al.   NEURON

P2Y1 receptors inhibit long-term depression in the prefrontal cortex

(2010) Segundo J. Guzman et al.   NEUROPHARMACOLOGY

Metabotropic glutamate receptors: From the workbench to the bedside

(2010) F. Nicoletti et al.   NEUROPHARMACOLOGY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Influence of the NR3A subunit on NMDA receptor functions

(2010) Maile A. Henson et al.   PROGRESS IN NEUROBIOLOGY

Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors

(2010) Roghayeh Khakpay et al.   Purinergic Signalling

Gliotransmission: Exocytotic release from astrocytes

(2009) Vladimir Parpura et al.   BRAIN RESEARCH REVIEWS

Tuning and Fine-Tuning of Synapses with Adenosine

(2009) A. Sebastiao et al.   Current Neuropharmacology

Characterization of the Potent and Highly Selective A2A Receptor Antagonists Preladenant and SCH 412348 [7-[2-[4-2,4-Difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in Rodent Models of Movement Disorders and Depression

(2009) R. A. Hodgson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Activity-dependent synaptic plasticity of NMDA receptors

(2009) Nelson Rebola et al.   JOURNAL OF PHYSIOLOGY-LONDON

Remodeling of striatal NMDA receptors by chronic A2A receptor blockade in Huntington's disease mice

(2009) Alberto Martire et al.   NEUROBIOLOGY OF DISEASE

Dual Palmitoylation of NR2 Subunits Regulates NMDA Receptor Trafficking

(2009) Takashi Hayashi et al.   NEURON

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON

Adenosine A2A Receptor Modulation of Hippocampal CA3-CA1 Synapse Plasticity During Associative Learning in Behaving Mice

(2009) Bruno M Fontinha et al.   NEUROPSYCHOPHARMACOLOGY

Synergistic interactions of dopamine D1 and glutamate NMDA receptors in rat hippocampus and prefrontal cortex: Involvement of ERK1/2 signaling

(2009) K. Sarantis et al.   NEUROSCIENCE

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders

(2009) Rodrigo Machado-Vieira et al.   NEUROSCIENTIST

Endogenous nonneuronal modulators of synaptic transmission control cortical slow oscillations in vivo

(2009) T. Fellin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presynaptic and postsynaptic modulation of glutamatergic synaptic transmission by activation of α1- and β-adrenoceptors in layer V pyramidal neurons of rat cerebral cortex

(2009) Masayuki Kobayashi et al.   SYNAPSE

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons

(2008) Matthew Edward Pamenter et al.   BRAIN RESEARCH

Potential Therapeutic Interest of Adenosine A2A Receptors in Psychiatric Disorders

(2008) Rodrigo Cunha et al.   CURRENT PHARMACEUTICAL DESIGN

Plasmin Potentiates SynapticN-Methyl-D-aspartate Receptor Function in Hippocampal Neurons through Activation of Protease-activated Receptor-1

(2008) Guido Mannaioni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of 5-HT2A/CReceptors Counteracts 5-HT1ARegulation ofN-Methyl-D-aspartate Receptor Channels in Pyramidal Neurons of Prefrontal Cortex

(2008) Eunice Y. Yuen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Critical Role of the Adenosine A2A Receptor in Extrastriatal Neurons in Modulating Psychomotor Activity as Revealed by Opposite Phenotypes of Striatum and Forebrain A2A Receptor Knock-Outs

(2008) H.-Y. Shen et al.   JOURNAL OF NEUROSCIENCE

Assembly and forward trafficking of NMDA receptors (Review)

(2008) F. Anne Stephenson et al.   MOLECULAR MEMBRANE BIOLOGY

Shuffling the Deck Anew: How NR3 Tweaks NMDA Receptor Function

(2008) Nora A. Cavara et al.   MOLECULAR NEUROBIOLOGY

Purinergic signalling and disorders of the central nervous system

(2008) Geoffrey Burnstock   NATURE REVIEWS DRUG DISCOVERY

Adenosine A2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

(2008) Nelson Rebola et al.   NEURON

Blockade of glutamate transporters leads to potentiation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex via group II metabotropic glutamate receptor activation

(2008) Joao F. Oliveira et al.   NEUROPHARMACOLOGY

Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine

(2008) B.M. Fontinha et al.   NEUROPHARMACOLOGY

P2X receptors and synaptic plasticity

(2008) Y. Pankratov et al.   NEUROSCIENCE

Prefrontal cortex–nucleus accumbens interaction: In vivo modulation by dopamine and glutamate in the prefrontal cortex

(2008) Alberto Del Arco et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Purinergic signalling in the nervous system: an overview

(2008) Maria P. Abbracchio et al.   TRENDS IN NEUROSCIENCES

Adenosine as a neuromodulator in neurological diseases

(2007) D BOISON   CURRENT OPINION IN PHARMACOLOGY

Long-term potentiation inhibition by low-levelN-methyl-D-aspartate receptor activation involves calcineurin, nitric oxide, and p38 mitogen-activated protein kinase

(2007) Yukitoshi Izumi et al.   HIPPOCAMPUS