Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma

Multiple facets of p53 in senescence induction and maintenance

(2016) Yoshikazu Johmura et al.   CANCER SCIENCE

Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

(2016) Miika Mehine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Mediates Tumor Suppression via Cellular Senescence

(2016) Lorenzo Galluzzi et al.   TRENDS IN CELL BIOLOGY

SCFFbxo22-KDM4A targets methylated p53 for degradation and regulates senescence

(2016) Yoshikazu Johmura et al.   Nature Communications

Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas

(2016) V. Vidimar et al.   Science Advances

Detection ofWIPI1mRNA as an indicator of autophagosome formation

(2014) Satoshi Tsuyuki et al.   Autophagy

Inactivation of AKT Induces Cellular Senescence in Uterine Leiomyoma

(2014) Xiaofei Xu et al.   ENDOCRINOLOGY

Down-Regulation of miR-29b Is Essential for Pathogenesis of Uterine Leiomyoma

(2014) Wenan Qiang et al.   ENDOCRINOLOGY

Fibroid growth and medical options for treatment

(2014) Nathalie Chabbert-Buffet et al.   FERTILITY AND STERILITY

Characterization of novel markers of senescence and their prognostic potential in cancer

(2014) M Althubiti et al.   Cell Death & Disease

Uterine Fibroids

(2013) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Expression analysis of MIR182 and its associated target genes in advanced ovarian carcinoma

(2012) Brian D McMillen et al.   MODERN PATHOLOGY

Induction of Cellular Senescence by Doxorubicin Is Associated with Upregulated miR-375 and Induction of Autophagy in K562 Cells

(2012) Ming-Yu Yang et al.   PLoS One

Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium

(2012) Dominique N Markowski et al.   BMC Womens Health

Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

(2011) Vilde D Haakensen et al.   BMC CANCER

WIPI1 Coordinates Melanogenic Gene Transcription and Melanosome Formation via TORC1 Inhibition

(2011) Hsiang Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

(2011) Alyssa L. Kennedy et al.   MOLECULAR CELL

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

AMPK-independent induction of autophagy by cytosolic Ca2+ increase

(2010) Antje Grotemeier et al.   CELLULAR SIGNALLING

Progesterone Is Essential for Maintenance and Growth of Uterine Leiomyoma

(2010) Hiroshi Ishikawa et al.   ENDOCRINOLOGY

Cellular senescence in usual type uterine leiomyoma

(2009) Jordan Laser et al.   FERTILITY AND STERILITY

Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells

(2009) Wolfgang Wagner et al.   PLoS One

Growth of uterine leiomyomata among premenopausal black and white women

(2008) S. D. Peddada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA