Gradient generation platforms: new directions for an established microfluidic technology

A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

(2014) Simone Bersini et al.   BIOMATERIALS

Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis

(2014) S. P. Cavnar et al.   Integrative Biology

A microfluidic coculture and multiphoton FAD analysis assay provides insight into the influence of the bone microenvironment on prostate cancer cells

(2014) Lauren L. Bischel et al.   Integrative Biology

Lymphocyte Electrotaxis In Vitro and In Vivo

(2014) F. Lin et al.   JOURNAL OF IMMUNOLOGY

The present and future role of microfluidics in biomedical research

(2014) Eric K. Sackmann et al.   NATURE

Characterizing asthma from a drop of blood using neutrophil chemotaxis

(2014) E. K.-H. Sackmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On-Chip Evaluation of Neutrophil Activation and Neutrophil–Endothelial Cell Interaction during Neutrophil Chemotaxis

(2013) Donghyuk Kim et al.   ANALYTICAL CHEMISTRY

A microfluidic device mimicking acinar concentration gradients across the liver acinus

(2013) Ming-Cheng Shih et al.   BIOMEDICAL MICRODEVICES

Gradient sensing during chemotaxis

(2013) Tian Jin   CURRENT OPINION IN CELL BIOLOGY

Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels

(2013) Bashar Hamza et al.   Integrative Biology

Investigating Axonal Guidance with Microdevice-Based Approaches

(2013) I. Dupin et al.   JOURNAL OF NEUROSCIENCE

Understanding the Impact of 2D and 3D Fibroblast Cultures on In Vitro Breast Cancer Models

(2013) Kyung Eun Sung et al.   PLoS One

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct cell shapes determine accurate chemotaxis

(2013) Luke Tweedy et al.   Scientific Reports

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

(2013) Erwin Berthier et al.   PLoS Pathogens

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels

(2012) Lauren L. Bischel et al.   BIOMATERIALS

Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays

(2012) E. K. Sackmann et al.   BLOOD

Multiscale mechanisms of cell migration during development: theory and experiment

(2012) R. McLennan et al.   DEVELOPMENT

Kit-On-A-Lid-Assays for accessible self-contained cell assays

(2012) Erwin Berthier et al.   LAB ON A CHIP

Blood vessels on a chip

(2012) Claudio Franco et al.   NATURE

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Chemoattractant Signaling in Dictyostelium: Adaptation and Amplification

(2012) P. A. Iglesias   Science Signaling

Gradient biomaterials for soft-to-hard interface tissue engineering

(2011) Azadeh Seidi et al.   Acta Biomaterialia

Hax1 regulates neutrophil adhesion and motility through RhoA

(2011) Peter J. Cavnar et al.   JOURNAL OF CELL BIOLOGY

Image-based analysis of primary human neutrophil chemotaxis in an automated direct-viewing assay

(2011) Ivar Meyvantsson et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Phospholipase C- 3 Is a Key Modulator of IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells

(2011) V. Bezzerri et al.   JOURNAL OF IMMUNOLOGY

Fluid forces control endothelial sprouting

(2011) J. W. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular matrix determinants of proteolytic and non-proteolytic cell migration

(2011) Katarina Wolf et al.   TRENDS IN CELL BIOLOGY

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Microfluidic Technologies for Temporal Perturbations of Chemotaxis

(2010) Daniel Irimia   Annual Review of Biomedical Engineering

Eukaryotic Chemotaxis: A Network of Signaling Pathways Controls Motility, Directional Sensing, and Polarity

(2010) Kristen F. Swaney et al.   Annual Review of Biophysics

A microfluidic platform for generation of sharp gradients in open-access culture

(2010) David M. Cate et al.   Biomicrofluidics

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

An arrayed high-content chemotaxis assay for patient diagnosis

(2010) Erwin Berthier et al.   Integrative Biology

Directional decisions during neutrophil chemotaxis inside bifurcating channels

(2010) Vijayakrishnan Ambravaneswaran et al.   Integrative Biology

Clinical microfluidics for neutrophil genomics and proteomics

(2010) Kenneth T Kotz et al.   NATURE MEDICINE

Burn Injury Reduces Neutrophil Directional Migration Speed in Microfluidic Devices

(2010) Kathryn L. Butler et al.   PLoS One

An Improved Chamber for Direct Visualisation of Chemotaxis

(2010) Andrew J. Muinonen-Martin et al.   PLoS One

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Spontaneous migration of cancer cells under conditions of mechanical confinement

(2009) Daniel Irimia et al.   Integrative Biology

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Selective and tunable gradient device for cell culture and chemotaxis study

(2009) Dongshin Kim et al.   LAB ON A CHIP

Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient

(2009) Joong Yull Park et al.   STEM CELLS

Chemotaxis: finding the way forward with Dictyostelium

(2009) Jason S. King et al.   TRENDS IN CELL BIOLOGY

Directional sensing during chemotaxis

(2008) Christopher Janetopoulos et al.   FEBS LETTERS

Neutrophil migration assay from a drop of blood

(2008) Nitin Agrawal et al.   LAB ON A CHIP

A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment

(2008) Vinay V. Abhyankar et al.   LAB ON A CHIP

Managing evaporation for more robust microscale assays : Part 1. Volume loss in high throughput assays

(2008) Erwin Berthier et al.   LAB ON A CHIP

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP

A multi-purpose microfluidic perfusion system with combinatorial choice of inputs, mixtures, gradient patterns, and flow rates

(2008) Gregory A. Cooksey et al.   LAB ON A CHIP

Surface-Bound Soft Matter Gradients

(2008) Jan Genzer et al.   LANGMUIR

Biomolecular gradients in cell culture systems

(2007) Thomas M. Keenan et al.   LAB ON A CHIP