Understanding the Impact of 2D and 3D Fibroblast Cultures on In Vitro Breast Cancer Models

Enabling screening in 3D microenvironments: probing matrix and stromal effects on the morphology and proliferation of T47D breast carcinoma cells

(2013) Sara I. Montanez-Sauri et al.   Integrative Biology

HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop

(2011) Zanobia A Syed et al.   BMC CANCER

3D trumps 2D when studying endothelial cells

(2010) C. P. Blobel   BLOOD

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

(2010) Kyung Eun Sung et al.   Integrative Biology

Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival

(2010) Virginia Espina et al.   PLoS One

Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

(2010) K. D. Grugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocrine TGF-  and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

(2010) Y. Kojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices

(2009) Kyung Eun Sung et al.   BIOMATERIALS

Gain in cellular organization of inflammatory breast cancer: A 3D in vitro model that mimics the in vivo metastasis

(2009) Jorge Morales et al.   BMC CANCER

Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ

(2009) M. Sharma et al.   BREAST CANCER RESEARCH AND TREATMENT

Decreased TGFβ signaling and increased COX2 expression in high risk women with increased mammographic breast density

(2009) Wei Tse Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Fibroblast Hepatocyte Growth Factor Promotes Invasion of Human Mammary Ductal Carcinoma In situ

(2009) C. Jedeszko et al.   CANCER RESEARCH

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cellular observations enabled by microculture: paracrine signaling and population demographics

(2009) Maribella Domenech et al.   Integrative Biology

Extracting diagnostic stromal organization features based on intrinsic two-photon excited fluorescence and second-harmonic generation signals

(2009) Shuangmu Zhuo et al.   JOURNAL OF BIOMEDICAL OPTICS

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: Inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma

(2009) C.-F. Gao et al.   MOLECULAR CANCER THERAPEUTICS

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

(2009) Pierre Farmer et al.   NATURE MEDICINE

Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast

(2009) M. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

(2009) C. Fischbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments

(2008) Amy P. Wong et al.   BIOMATERIALS

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Regulation of In Situ to Invasive Breast Carcinoma Transition

(2008) Min Hu et al.   CANCER CELL

Cyclooxygenase-2 Expression during Immortalization and Breast Cancer Progression

(2008) X. Zhao et al.   CANCER RESEARCH

Three-dimensional context regulation of metastasis

(2008) Janine T. Erler et al.   CLINICAL & EXPERIMENTAL METASTASIS

Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging

(2008) Cyrus M. Ghajar et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Second-harmonic generation in collagen as a potential cancer diagnostic parameter

(2008) Tord Hompland et al.   JOURNAL OF BIOMEDICAL OPTICS

Managing evaporation for more robust microscale assays : Part 2. Characterization of convection and diffusion for cell biology

(2008) Erwin Berthier et al.   LAB ON A CHIP

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

(2008) Seok Chung et al.   LAB ON A CHIP

Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma

(2008) Xiaoxing Han et al.   OPTICS EXPRESS

Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs

(2008) Y. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA