Thinking big by thinking small: application of microfluidic technology to improve ART

Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?

(2012) Marcos Meseguer et al.   FERTILITY AND STERILITY

Three-Dimensional Rotation of Mouse Embryos

(2012) Clement Leung et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

High-throughput optofluidic system for the laser microsurgery of oocytes

(2012) Charlie Chandsawangbhuwana et al.   JOURNAL OF BIOMEDICAL OPTICS

It is Time for a Change: Petri Dishes Weaken Cells

(2012) Andrei P. Sommer et al.   Journal of Bionic Engineering

Lab-on-a-chip biophotonics: its application to assisted reproductive technologies

(2012) David Lai et al.   Journal of Biophotonics

Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation

(2012) Yun Seok Heo et al.   LAB ON A CHIP

Miniaturized Embryo Array for Automated Trapping, Immobilization and Microperfusion of Zebrafish Embryos

(2012) Jin Akagi et al.   PLoS One

Effect of Substrate Stiffness on Early Mouse Embryo Development

(2012) Kevin S. Kolahi et al.   PLoS One

Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

(2012) Shawn L. Chavez et al.   Nature Communications

In Vitro Fertilization on a Single-Oocyte Positioning System Integrated with Motile Sperm Selection and Early Embryo Development

(2011) Rui Ma et al.   ANALYTICAL CHEMISTRY

Mechanical stimulation of bovine embryos in a microfluidic culture platform

(2011) Chae Yun Bae et al.   BioChip Journal

Rethinking In Vitro Embryo Culture: New Developments in Culture Platforms and Potential to Improve Assisted Reproductive Technologies1

(2011) Gary D. Smith et al.   BIOLOGY OF REPRODUCTION

Microfluidic dynamic embryo culture increases the production of top quality human embryos through reduction in embryo fragmentation

(2011) J.R. Alegretti et al.   FERTILITY AND STERILITY

Development of a microfluidic device for automated vitrification human embryo

(2011) L. Meng et al.   FERTILITY AND STERILITY

Advances in embryo culture platforms: novel approaches to improve preimplantation embryo development through modifications of the microenvironment

(2011) J. E. Swain et al.   HUMAN REPRODUCTION UPDATE

Robotic ICSI (Intracytoplasmic Sperm Injection)

(2011) Zhe Lu et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform

(2011) Yun Seok Heo et al.   LAB ON A CHIP

On-chip magnetically actuated robot with ultrasonic vibration for single cell manipulations

(2011) Masaya Hagiwara et al.   LAB ON A CHIP

In-vitro culture of human embryos with mechanical micro-vibration increases implantation rates

(2011) Vladimir Isachenko et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Screening of sperm velocity by fluid mechanical characteristics of a cyclo-olefin polymer microfluidic sperm-sorting device

(2011) Koji Matsuura et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Integration of Sperm Motility and Chemotaxis Screening with a Microchannel-Based Device

(2010) L. Xie et al.   CLINICAL CHEMISTRY

Comet assay on mouse oocytes: an improved technique to evaluate genotoxic risk on female germ cells

(2010) Anais Berthelot-Ricou et al.   FERTILITY AND STERILITY

Dynamic microfunnel culture enhances mouse embryo development and pregnancy rates

(2010) Y.S. Heo et al.   HUMAN REPRODUCTION

On-Chip Single Embryo Coculture With Microporous-Membrane-Supported Endometrial Cells

(2010) H. Kimura et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

In-vitro Culture with a Tilting Device in Chemically Defined Media During Meiotic Maturation and Early Development Improves the Quality of Blastocysts Derived from In-vitro Matured and Fertilized Porcine Oocytes

(2010) Takayuki KOIKE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Enhancement of Cytoplasmic Maturation of In Vitro-Matured Pig Oocytes by Mechanical Vibration

(2010) Yamato MIZOBE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

On-chip determination of spermatozoa concentration using electrical impedance measurements

(2010) Loes I. Segerink et al.   LAB ON A CHIP

Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device

(2010) Chao Han et al.   LAB ON A CHIP

Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage

(2010) Connie C Wong et al.   NATURE BIOTECHNOLOGY

Application of a microfluidic sperm sorter to the in-vitro fertilization of porcine oocytes reduced the incidence of polyspermic penetration

(2010) Hikaru Sano et al.   THERIOGENOLOGY

A microfluidicin vitrocultivation system for mechanical stimulation of bovine embryos

(2009) Minseok S. Kim et al.   ELECTROPHORESIS

Blastocyst Microinjection Automation

(2009) L.S. Mattos et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

Improved development of mouse and human embryos using a tilting embryo culture system

(2009) Koji Matsuura et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Noninvasive Metabolic Profiling Using Microfluidics for Analysis of Single Preimplantation Embryos

(2008) John Paul Urbanski et al.   ANALYTICAL CHEMISTRY

Sperm motion in a microfluidic fertilization device

(2008) M. d. C. Lopez-Garcia et al.   BIOMEDICAL MICRODEVICES