Conversion of psychological stress into cellular stress response: Roles of the sigma-1 receptor in the process

The -116C/G polymorphism inXBP1gene is associated with psychiatric illness in Asian population: A meta-analysis

(2014) Dan Cheng et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update

(2014) Serge N. Manié et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis

(2014) Hideaki Tagashira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Aberrant neuronal differentiation and inhibition of dendrite outgrowth resulting from endoplasmic reticulum stress

(2014) Koichi Kawada et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and Longevity

(2014) E. S. Epel et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

0073 PTSD and Cognitive Impairment among Rescue and Recovery Workers exposed to the 9/11 World Trade Centre Disaster

(2014) Sadie Sanchez et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Pregnenolone treatment reduces severity of negative symptoms in recent-onset schizophrenia: An 8-week, double-blind, randomized add-on two-center trial

(2014) Michael S. Ritsner et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Comparative study of cognitive impairment between medicated and medication-free patients with remitted major depression: Class-specific influence by tricyclic antidepressants and newer antidepressants

(2014) Akiko Nagane et al.   PSYCHIATRY RESEARCH

Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study

(2014) Lisa Nevell et al.   PSYCHONEUROENDOCRINOLOGY

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor

(2014) T Omi et al.   Cell Death & Disease

Integrated Neurobiology of Bipolar Disorder

(2014) Vladimir Maletic et al.   Frontiers in Psychiatry

Dynamic Interaction between Sigma-1 Receptor and Kv1.2 Shapes Neuronal and Behavioral Responses to Cocaine

(2013) Saïd Kourrich et al.   CELL

Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population

(2013) Malgorzata Kowalczyk et al.   CELL STRESS & CHAPERONES

Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions

(2013) Jose Luis Ortega-Roldan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

(2013) Marco Peviani et al.   NEUROBIOLOGY OF DISEASE

Role of hydrogen sulfide in secondary neuronal injury

(2013) Jun-Feng Wang et al.   NEUROCHEMISTRY INTERNATIONAL

Lack of sigma-1 receptor exacerbates ALS progression in mice

(2013) T.A. Mavlyutov et al.   NEUROSCIENCE

SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models

(2013) Yoko Ono et al.   NEUROSCIENCE LETTERS

Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival

(2013) Tomohisa Mori et al.   PLoS One

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

(2013) L. Hedskog et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Psychological stress, immune response, and atherosclerosis

(2012) Hong-feng Gu et al.   ATHEROSCLEROSIS

Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic Pathways: Therapeutic Effects

(2012) Henry A. Lester et al.   BIOLOGICAL PSYCHIATRY

The Lifetime of UDP-galactose:Ceramide Galactosyltransferase Is Controlled by a Distinct Endoplasmic Reticulum-associated Degradation (ERAD) Regulated by Sigma-1 Receptor Chaperones

(2012) Teruo Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological parainflammation and endoplasmic reticulum stress in depression: potential translational targets through the CNS insulin, klotho and PPAR-γ systems

(2012) P W Gold et al.   MOLECULAR PSYCHIATRY

MicroRNAs miR-144/144* and miR-16 in peripheral blood are potential biomarkers for naturalistic stress in healthy Japanese medical students

(2012) Sakurako Katsuura et al.   NEUROSCIENCE LETTERS

Sigma-1R Agonist Improves Motor Function and Motoneuron Survival in ALS Mice

(2012) Renzo Mancuso et al.   Neurotherapeutics

Effects of the Sigma-1 Receptor Agonist 1-(3,4-Dimethoxyphenethyl)-4-(3-Phenylpropyl)-Piperazine Dihydro-Chloride on Inflammation after Stroke

(2012) Karsten Ruscher et al.   PLoS One

A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis

(2011) Amr Al-Saif et al.   ANNALS OF NEUROLOGY

Sigma-1Rs are upregulated via PERK/eIF2α/ATF4 pathway and execute protective function in ER stress

(2011) Teruhiko Mitsuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors

(2011) Karin Weigelt et al.   BRAIN BEHAVIOR AND IMMUNITY

Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats

(2011) Mohammad Allahtavakoli et al.   BRAIN RESEARCH BULLETIN

Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

(2011) Teruo Hayashi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Pharmacological Interaction With the Sigma1 (σ1)-Receptor in the Acute Behavioral Effects of Antidepressants

(2011) Vanessa Villard et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity

(2011) Vittorio Calabrese et al.   MOLECULAR ASPECTS OF MEDICINE

Signaling pathways underlying the rapid antidepressant actions of ketamine

(2011) Ronald S. Duman et al.   NEUROPHARMACOLOGY

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Insights into the Sigma-1 receptor Chaperone's cellular functions: A microarray report

(2011) Shang-Yi Tsai et al.   SYNAPSE

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

(2011) Jinbin Xu et al.   Nature Communications

Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease

(2010) Agnes A. Luty et al.   ANNALS OF NEUROLOGY

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

(2010) Riccardo Bernasconi et al.   CURRENT OPINION IN CELL BIOLOGY

An integrated genomic analysis of gene-function correlation on schizophrenia susceptibility genes

(2010) Tearina T Chu et al.   JOURNAL OF HUMAN GENETICS

Elevated Delta-6 desaturase (FADS2) gene expression in the prefrontal cortex of patients with bipolar disorder

(2010) Yanhong Liu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

DHEA prevents Aβ25–35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling

(2010) Liang Li et al.   NEUROPHARMACOLOGY

Association analysis of SIGMAR1 with major depressive disorder and SSRI response

(2010) Taro Kishi et al.   NEUROPHARMACOLOGY

The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study

(2010) T.A. Mavlyutov et al.   NEUROSCIENCE

The sigma-1 receptor chaperone as an inter-organelle signaling modulator

(2010) Tsung-Ping Su et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Sigma-1 Receptors Regulate Bcl-2 Expression by Reactive Oxygen Species-Dependent Transcriptional Regulation of Nuclear Factor  B

(2009) J. Meunier et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression

(2009) Tuerhong Tuerxun et al.   NEUROSCIENCE LETTERS

Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1·GTP pathway

(2009) Shang-Yi Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agonistic encounters and cellular angst: social interactions induce heat shock proteins in juvenile salmonid fish

(2009) S. Currie et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders

(2009) Byungsu Kim et al.   PSYCHIATRY RESEARCH

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

Sigma-1 receptor knockout mice display a depressive-like phenotype

(2008) Valentina Sabino et al.   BEHAVIOURAL BRAIN RESEARCH

Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1

(2008) Akiko Hayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder

(2008) Akiko Hayashi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth by Fluvoxamine: Role of Sigma-1 Receptors, IP3 Receptors and Cellular Signaling Pathways

(2008) Tomoko Nishimura et al.   PLoS One

Mitochondria in multiple sclerosis

(2007) Pedram Ghafourifar   Frontiers in Bioscience-Landmark