Aging Exacerbates Obesity-Induced Oxidative Stress and Inflammation in Perivascular Adipose Tissue in Mice: A Paracrine Mechanism Contributing to Vascular Redox Dysregulation and Inflammation

Long-term Assessment of Inflammation and Healthy Aging in Late Life: The Cardiovascular Health Study All Stars

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Immunological complications of obesity

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High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production

(2011) Christine Ruggiero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

(2011) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response

(2011) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice

(2011) M.K. Öhman et al.   ATHEROSCLEROSIS

Epicardial perivascular adipose tissue as a therapeutic target in obesity-related coronary artery disease

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Translational evidence of endothelial damage in obese individuals: inflammatory and prothrombotic responses

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Linking the inflammasome to obesity-related disease

(2011) Tiffany Horng et al.   NATURE MEDICINE

Oxidative Stress Accumulates in Adipose Tissue during Aging and Inhibits Adipogenesis

(2011) Hannes M. Findeisen et al.   PLoS One

Weight loss in obese C57BL/6 mice limits adventitial expansion of established angiotensin II-induced abdominal aortic aneurysms

(2010) Sara B. Police et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Monocyte Chemoattractant Protein-1 Deficiency Protects Against Visceral Fat-Induced Atherosclerosis

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Epicardial Perivascular Adipose-Derived Leptin Exacerbates Coronary Endothelial Dysfunction in Metabolic Syndrome via a Protein Kinase C-β Pathway

(2010) Gregory A. Payne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Perivascular adipose tissue as a cause of atherosclerosis

(2010) Sandra N. Verhagen et al.   ATHEROSCLEROSIS

Periadventitial Adipose Tissue Promotes Endothelial Dysfunction via Oxidative Stress in Diet-Induced Obese C57Bl/6 Mice

(2010) Juha Ketonen et al.   CIRCULATION JOURNAL

Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue-Derived Microvascular Endothelial Cells

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NOX activity in brain aging: Exacerbation by high fat diet

(2010) Annadora J. Bruce-Keller et al.   FREE RADICAL BIOLOGY AND MEDICINE

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

(2010) Christopher D. Morrison et al.   JOURNAL OF NEUROCHEMISTRY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Augmented Superoxide Production By Nox2-Containing NADPH Oxidase Causes Cerebral Artery Dysfunction During Hypercholesterolemia

(2010) Alyson A. Miller et al.   STROKE

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Obesity Promotes Inflammation in Periaortic Adipose Tissue and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation

(2009) Sara B. Police et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial Nitric Oxide Synthase Uncoupling and Perivascular Adipose Oxidative Stress and Inflammation Contribute to Vascular Dysfunction in a Rodent Model of Metabolic Syndrome

(2009) Chiara Marchesi et al.   HYPERTENSION

Early-onset GH deficiency results in spatial memory impairment in mid-life and is prevented by GH supplementation

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Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1

(2009) Anna Csiszar et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Obesity Increases Vascular Senescence and Susceptibility to Ischemic Injury Through Chronic Activation of Akt and mTOR

(2009) C.-Y. Wang et al.   Science Signaling

Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats

(2008) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms Underlying Caloric Restriction and Lifespan Regulation

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