Drafting the proteome landscape of myeloid-derived suppressor cells

Top–down analysis of low mass proteins in exosomes shed by murine myeloid-derived suppressor cells

(2015) Lucía Geis-Asteggiante et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Therapy-induced tumour secretomes promote resistance and tumour progression

(2015) Anna C. Obenauf et al.   NATURE

Compartment resolved reference proteome map from highly purified naïve, activated, effector, and memory CD8+murine immune cells

(2015) Damien Zanker et al.   PROTEOMICS

Quantitative mass spectrometry of posttranslational modifications: Keys to confidence

(2015) Marco Leo Hennrich et al.   Science Signaling

Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer

(2015) Inès Dufait et al.   Oncotarget

Quantitative mass spectrometry of posttranslational modifications: Keys to confidence

(2015) Marco Leo Hennrich et al.   Science Signaling

Establishment of lal-/- Myeloid Lineage Cell Line That Resembles Myeloid-Derived Suppressive Cells

(2015) Xinchun Ding et al.   PLoS One

Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer

(2015) Alexander M. Aliper et al.   Oncotarget

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice

(2015) Therese Liechtenstein et al.   Oncotarget

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity

(2015) Kevin Van der Jeught et al.   Oncotarget

Myeloid-derived suppressor cell heterogeneity in human cancers

(2014) Samantha Solito et al.   Annals of the New York Academy of Sciences

Chemotherapeutic Targeting of Cancer-Induced Immunosuppressive Cells

(2014) D. Alizadeh et al.   CANCER RESEARCH

System level dynamics of post-translational modifications

(2014) Aaron S Gajadhar et al.   CURRENT OPINION IN BIOTECHNOLOGY

Complexity and challenges in defining myeloid-derived suppressor cells

(2014) Vera Damuzzo et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis

(2014) Thomas Condamine et al.   JOURNAL OF CLINICAL INVESTIGATION

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Ubiquitinated Proteins in Exosomes Secreted by Myeloid-Derived Suppressor Cells

(2014) Meghan C. Burke et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative shotgun proteomics: considerations for a high-quality workflow in immunology

(2014) Felix Meissner et al.   NATURE IMMUNOLOGY

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells

(2014) Emmanuelle Thinon et al.   Nature Communications

Location, location, location: functional and phenotypic heterogeneity between tumor-infiltrating and non-infiltrating myeloid-derived suppressor cells

(2014) Sarah K Maenhout et al.   OncoImmunology

Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized usingex vivomyeloid-derived suppressor cells as a readout of therapeutic efficacy

(2014) Therese Liechtenstein et al.   OncoImmunology

Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma

(2013) Jedd D. Wolchok et al.   Annals of the New York Academy of Sciences

Methodologies to decipher the cell secretome

(2013) Paromita Mukherjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer

(2013) D. Alizadeh et al.   CANCER RESEARCH

Advances in characterizing ubiquitylation sites by mass spectrometry

(2013) Kathrine B Sylvestersen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Phosphoproteomics in drug discovery

(2013) Melody K. Morris et al.   DRUG DISCOVERY TODAY

Enhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared with their peripheral counterparts

(2013) Sarah K. Maenhout et al.   INTERNATIONAL JOURNAL OF CANCER

The ubiquitin code and its decoding machinery in the endocytic pathway

(2013) H. Tanno et al.   JOURNAL OF BIOCHEMISTRY

T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes

(2013) Isabel Bochmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exosomes from Myeloid-Derived Suppressor Cells Carry Biologically Active Proteins

(2013) Meghan Burke et al.   JOURNAL OF PROTEOME RESEARCH

Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry

(2013) Jesper V. Olsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

(2013) Jean-Philippe Lambert et al.   NATURE METHODS

Direct Proteomic Quantification of the Secretome of Activated Immune Cells

(2013) F. Meissner et al.   SCIENCE

Mass spectrometry-driven phosphoproteomics: patterning the systems biology mosaic

(2013) Martin A. Jünger et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Assessing T-cell responses in anticancer immunotherapy

(2013) David Escors et al.   OncoImmunology

Selective Activation of Intracellular Signalling Pathways in Dendritic Cells for Cancer Immunotherapy

(2012) Frederick Arce et al.   Anti-Cancer Agents in Medicinal Chemistry

Advances in the proteomic investigation of the cell secretome

(2012) Kristy J Brown et al.   Expert Review of Proteomics

Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III

(2012) Paul C. Schröder et al.   Journal of Proteomics

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

To label or not to label: Applications of quantitative proteomics in neuroscience research

(2012) Michaela D. Filiou et al.   PROTEOMICS

Profiling of the human monocytic cell secretome by quantitative label-free mass spectrometry identifies stimulus-specific cytokines and proinflammatory proteins

(2012) M. Groessl et al.   PROTEOMICS

Dendritic Cells for Active Anti-Cancer Immunotherapy: Targeting Activation Pathways Through Genetic Modification

(2012) Karine Breckpot et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

PD-L1 co-stimulation, ligand-induced TCR down-modulation and anti-tumor immunotherapy

(2012) Katarzyna Karwacz et al.   OncoImmunology

Strategies and tools to explore protein S-nitrosylation

(2011) Karthik Raju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells

(2011) N. Obermajer et al.   BLOOD

Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis

(2011) Angela M. Boutté et al.   FASEB JOURNAL

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

(2011) Shitao Li et al.   IMMUNITY

Proteomic databases and tools to decipher post-translational modifications

(2011) Karthik S. Kamath et al.   Journal of Proteomics

Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics

(2011) Angela M. Boutté et al.   PLoS One

Less label, more free: Approaches in label-free quantitative mass spectrometry

(2011) Karlie A. Neilson et al.   PROTEOMICS

Endosomal transport via ubiquitination

(2011) Robert C. Piper et al.   TRENDS IN CELL BIOLOGY

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers

(2010) K. N. Kodumudi et al.   CLINICAL CANCER RESEARCH

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

Proteomic Pathway Analysis Reveals Inflammation Increases Myeloid-Derived Suppressor Cell Resistance to Apoptosis

(2010) Olesya Chornoguz et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass Spectrometry Based Glycoproteomics—From a Proteomics Perspective

(2010) Sheng Pan et al.   MOLECULAR & CELLULAR PROTEOMICS

Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS

(2010) Richard D Unwin et al.   Nature Protocols

Screening of Human Tumor Antigens for CD4+ T Cell Epitopes by Combination of HLA-Transgenic Mice, Recombinant Adenovirus and Antigen Peptide Libraries

(2010) Wolfram Osen et al.   PLoS One

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

(2010) Thomas Condamine et al.   TRENDS IN IMMUNOLOGY

bioDBnet: the biological database network

(2009) Uma Mudunuri et al.   BIOINFORMATICS

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

(2009) Johanna K. Morales et al.   BREAST CANCER RESEARCH AND TREATMENT

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL4Rα + Myeloid-Derived Suppressor Cell Expansion in Cancer Patients

(2009) Susanna Mandruzzato et al.   JOURNAL OF IMMUNOLOGY

Cancer immunoediting and “spontaneous” tumor regression

(2009) Neel Sengupta et al.   PATHOLOGY RESEARCH AND PRACTICE

Immunosuppressive CD14+HLA-DRlow/−monocytes in prostate cancer

(2009) Stanimir Vuk-Pavlović et al.   PROSTATE

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Induction of myeloid-derived suppressor cells by tumor exosomes

(2008) Xiaoyu Xiang et al.   INTERNATIONAL JOURNAL OF CANCER