In silicomutational studies of Hsp70 disclose sites with distinct functional attributes

Protein Sectors: Statistical Coupling Analysis versus Conservation

(2015) Tiberiu Teşileanu et al.   PLoS Computational Biology

ATPase Subdomain IA Is a Mediator of Interdomain Allostery in Hsp70 Molecular Chaperones

(2014) Ignacio J. General et al.   PLoS Computational Biology

Parallel dynamics and evolution: Protein conformational fluctuations and assembly reflect evolutionary changes in sequence and structure

(2013) Joseph A. Marsh et al.   BIOESSAYS

ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function

(2013) Gershon Celniker et al.   ISRAEL JOURNAL OF CHEMISTRY

Plasmodium falciparumHsp70-x: a heat shock protein at the host–parasite interface

(2013) Rowan Hatherley et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Site-Specific Structural Constraints on Protein Sequence Evolutionary Divergence: Local Packing Density versus Solvent Exposure

(2013) So-Wei Yeh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

(2013) R. Rosenzweig et al.   SCIENCE

Hsp70 chaperone dynamics and molecular mechanism

(2013) Matthias P. Mayer   TRENDS IN BIOCHEMICAL SCIENCES

Identification of Key Hinge Residues Important for Nucleotide-Dependent Allostery in E. coli Hsp70/DnaK

(2013) Peter Man-Un Ung et al.   PLoS Computational Biology

Decipher the Mechanisms of Protein Conformational Changes Induced by Nucleotide Binding through Free-Energy Landscape Analysis: ATP Binding to Hsp70

(2013) Adrien Nicolaï et al.   PLoS Computational Biology

Network-Based Models as Tools Hinting at Nonevident Protein Functionality

(2012) Canan Atilgan et al.   Annual Review of Biophysics

Structural and dynamical analysis of biological networks

(2012) Cecilia Klein et al.   Briefings in Functional Genomics

Local motifs in proteins combine to generate global functional moves

(2012) A. R. Atilgan et al.   Briefings in Functional Genomics

Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones

(2012) Roman Kityk et al.   MOLECULAR CELL

The spatial architecture of protein function and adaptation

(2012) Richard N. McLaughlin Jr et al.   NATURE

Insights into the Fold Organization of TIM Barrel from Interaction Energy Based Structure Networks

(2012) M. S. Vijayabaskar et al.   PLoS Computational Biology

Hot Spots for Allosteric Regulation on Protein Surfaces

(2011) Kimberly A. Reynolds et al.   CELL

The Four Hydrophobic Residues on the Hsp70 Inter-Domain Linker Have Two Distinct Roles

(2011) Divya Prasanna Kumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

(2011) A. Zhuravleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutagenesis Reveals the Complex Relationships between ATPase Rate and the Chaperone Activities ofEscherichia coliHeat Shock Protein 70 (Hsp70/DnaK)

(2010) Lyra Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Directed Evolution of the DnaK Chaperone: Mutations in the Lid Domain Result in Enhanced Chaperone Activity

(2010) Raphael A. Aponte et al.   JOURNAL OF MOLECULAR BIOLOGY

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

An interdomain sector mediating allostery in Hsp70 molecular chaperones

(2010) Robert G Smock et al.   Molecular Systems Biology

Assortative Mixing in Close-Packed Spatial Networks

(2010) Deniz Turgut et al.   PLoS One

Role of Hsp70 ATPase Domain Intrinsic Dynamics and Sequence Evolution in Enabling its Functional Interactions with NEFs

(2010) Ying Liu et al.   PLoS Computational Biology

Protein Sectors: Evolutionary Units of Three-Dimensional Structure

(2009) Najeeb Halabi et al.   CELL

Hsp70 Structure, Function, Regulation and Influence on Yeast Prions

(2009) Deepak Sharma et al.   PROTEIN AND PEPTIDE LETTERS

The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin

(2008) Jorge Cuéllar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY