Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2-containing membranes
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Title
Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2-containing membranes
Authors
Keywords
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Journal
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Volume 83, Issue 5, Pages 952-969
Publisher
Wiley
Online
2015-03-05
DOI
10.1002/prot.24792
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Related references
Note: Only part of the references are listed.- Structure and Regulatory Interactions of the Cytoplasmic Terminal Domains of Serotonin Transporter
- (2014) Cristina Fenollar-Ferrer et al. BIOCHEMISTRY
- Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood
- (2014) Joanne Ng et al. BRAIN
- Missense dopamine transporter mutations associate with adult parkinsonism and ADHD
- (2014) Freja H. Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Microsecond Molecular Dynamics Simulations of Lipid Mixing
- (2014) Chunkit Hong et al. LANGMUIR
- PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein
- (2014) Peter J Hamilton et al. Nature Chemical Biology
- OpenStructure: an integrated software framework for computational structural biology
- (2013) M. Biasini et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The cost of living in the membrane: A case study of hydrophobic mismatch for the multi-segment protein LeuT
- (2013) Sayan Mondal et al. CHEMISTRY AND PHYSICS OF LIPIDS
- De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder
- (2013) P J Hamilton et al. MOLECULAR PSYCHIATRY
- X-ray structure of dopamine transporter elucidates antidepressant mechanism
- (2013) Aravind Penmatsa et al. NATURE
- Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate
- (2013) F. Buchmayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chloride binding site of neurotransmitter sodium symporters
- (2013) A. K. Kantcheva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutational Analysis of the High-Affinity Zinc Binding Site Validates a Refined Human Dopamine Transporter Homology Model
- (2013) Thomas Stockner et al. PLoS Computational Biology
- Phosphatidylinositol 4,5-Biphosphate (PIP2) Lipids Regulate the Phosphorylation of Syntaxin N-Terminus by Modulating Both Its Position and Local Structure
- (2012) George Khelashvili et al. BIOCHEMISTRY
- Ion-Controlled Conformational Dynamics in the Outward-Open Transition from an Occluded State of LeuT
- (2012) Chunfeng Zhao et al. BIOPHYSICAL JOURNAL
- The solute carrier 6 family of transporters
- (2012) Stefan Bröer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue
- (2012) Hui Wang et al. EMBO REPORTS
- Phosphorylation of Dopamine Transporter Serine 7 Modulates Cocaine Analog Binding
- (2012) Amy E. Moritz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dopamine Transporter Phosphorylation Site Threonine 53 Regulates Substrate Reuptake and Amphetamine-stimulated Efflux
- (2012) James D. Foster et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
- (2012) Robert B. Best et al. Journal of Chemical Theory and Computation
- Attention Deficit/Hyperactivity Disorder-Derived Coding Variation in the Dopamine Transporter Disrupts Microdomain Targeting and Trafficking Regulation
- (2012) D. Sakrikar et al. JOURNAL OF NEUROSCIENCE
- Structural Intermediates in a Model of the Substrate Translocation Path of the Bacterial Glutamate Transporter Homologue GltPh
- (2012) Sebastian Stolzenberg et al. JOURNAL OF PHYSICAL CHEMISTRY B
- X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
- (2012) Harini Krishnamurthy et al. NATURE
- Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context
- (2012) Hui Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Insights into transport mechanism from LeuT engineered to transport tryptophan
- (2011) Chayne L Piscitelli et al. EMBO JOURNAL
- PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions
- (2011) Mats H. M. Olsson et al. Journal of Chemical Theory and Computation
- MATCH: An atom-typing toolset for molecular mechanics force fields
- (2011) Joseph D. Yesselman et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT
- (2011) M Laura Cremona et al. NATURE NEUROSCIENCE
- The Substrate-Driven Transition to an Inward-Facing Conformation in the Functional Mechanism of the Dopamine Transporter
- (2011) Jufang Shan et al. PLoS One
- OpenStructure: a flexible software framework for computational structural biology
- (2010) Marco Biasini et al. BIOINFORMATICS
- A Molecular Dynamics Investigation of Lipid Bilayer Perturbation by PIP2
- (2010) Dmitry Lupyan et al. BIOPHYSICAL JOURNAL
- The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines
- (2010) Sonja Sucic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder
- (2010) E. Bowton et al. JOURNAL OF NEUROSCIENCE
- Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types
- (2010) Jeffery B. Klauda et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site
- (2010) Chayne L. Piscitelli et al. NATURE
- CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes
- (2009) Sunhwan Jo et al. BIOPHYSICAL JOURNAL
- Modeling Membrane Deformations and Lipid Demixing upon Protein-Membrane Interaction: The BAR Dimer Adsorption
- (2009) George Khelashvili et al. BIOPHYSICAL JOURNAL
- A Closer Look at Amphetamine-Induced Reverse Transport and Trafficking of the Dopamine and Norepinephrine Transporters
- (2009) S. D. Robertson et al. MOLECULAR NEUROBIOLOGY
- Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods
- (2009) Kalyaneswar Mandal et al. PROTEIN SCIENCE
- Macromolecular Modeling with Rosetta
- (2008) Rhiju Das et al. Annual Review of Biochemistry
- Sodium-Coupled Neurotransmitter Transporters
- (2008) Baruch I. Kanner et al. CHEMICAL REVIEWS
- An Intracellular Interaction Network Regulates Conformational Transitions in the Dopamine Transporter
- (2008) Julie Kniazeff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant
- (2008) M. S. Mazei-Robison et al. JOURNAL OF NEUROSCIENCE
- A Juxtamembrane Mutation in the N Terminus of the Dopamine Transporter Induces Preference for an Inward-Facing Conformation
- (2008) B. Guptaroy et al. MOLECULAR PHARMACOLOGY
- Syntaxin 1A Interaction with the Dopamine Transporter Promotes Amphetamine-Induced Dopamine Efflux
- (2008) F. Binda et al. MOLECULAR PHARMACOLOGY
- The binding sites for cocaine and dopamine in the dopamine transporter overlap
- (2008) Thijs Beuming et al. NATURE NEUROSCIENCE
- NCBI BLAST: a better web interface
- (2008) M. Johnson et al. NUCLEIC ACIDS RESEARCH
- A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation
- (2008) S. K. Singh et al. SCIENCE
- Protein Diffusion on Charged Membranes: A Dynamic Mean-Field Model Describes Time Evolution and Lipid Reorganization
- (2007) George Khelashvili et al. BIOPHYSICAL JOURNAL
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