Cryo-EM structure of fatty acid synthase (FAS) fromRhodosporidium toruloidesprovides insights into the evolutionary development of fungal FAS

Modular Polyketide Synthases (PKSs): A New Model Fits All?

(2014) Alexander Rittner et al.   CHEMBIOCHEM

Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems

(2014) Martin Grininger   CURRENT OPINION IN STRUCTURAL BIOLOGY

Architectures of Whole-Module and Bimodular Proteins from the 6-Deoxyerythronolide B Synthase

(2014) Andrea L. Edwards et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a modular polyketide synthase

(2014) Somnath Dutta et al.   NATURE

Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase

(2014) Habib S.T. Bukhari et al.   STRUCTURE

Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector

(2014) Matteo Allegretti et al.   eLife

Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

(2013) Joseph A. Marsh et al.   CELL

7.5-Å Cryo-EM Structure of the Mycobacterial Fatty Acid Synthase

(2013) Daniel Boehringer et al.   JOURNAL OF MOLECULAR BIOLOGY

The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life

(2013) Joris Beld et al.   NATURAL PRODUCT REPORTS

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Solution Structure of the Tandem Acyl Carrier Protein Domains from a Polyunsaturated Fatty Acid Synthase Reveals Beads-on-a-String Configuration

(2013) Uldaeliz Trujillo et al.   PLoS One

Structure and Conformational Variability of the Mycobacterium tuberculosis Fatty Acid Synthase Multienzyme Complex

(2013) Luciano Ciccarelli et al.   STRUCTURE

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

(2013) Xiao-chen Bai et al.   eLife

Microbial conversion of biodiesel byproduct glycerol to triacylglycerols by oleaginous yeast Rhodosporidium toruloides and the individual effect of some impurities on lipid production

(2012) Jingyang Xu et al.   BIOCHEMICAL ENGINEERING JOURNAL

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

The structures of type I polyketide synthases

(2012) Adrian T. Keatinge-Clay   NATURAL PRODUCT REPORTS

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides

(2012) Zhiwei Zhu et al.   Nature Communications

Mechanism of Substrate Shuttling by the Acyl-Carrier Protein within the Fatty Acid Mega-Synthase

(2010) Claudio Anselmi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy

(2010) P. Gipson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and function of eukaryotic fatty acid synthases

(2010) Timm Maier et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Multimeric Options for the Auto-Activation of the Saccharomyces cerevisiae FAS Type I Megasynthase

(2009) Patrik Johansson et al.   STRUCTURE

The effect of glycerol as a sole and secondary substrate on the growth and fatty acid composition of Rhodotorula glutinis

(2008) Emily R. Easterling et al.   BIORESOURCE TECHNOLOGY

The Role of Tandem Acyl Carrier Protein Domains in Polyunsaturated Fatty Acid Biosynthesis

(2008) Hui Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of the fungal fatty acid synthase type I multienzyme complex

(2008) P. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of a Mammalian Fatty Acid Synthase

(2008) T. Maier et al.   SCIENCE