Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses against Human Cytomegalovirus in Mice

Epitope-Specific Humoral Responses to Human Cytomegalovirus Glycoprotein-B Vaccine With MF59: Anti-AD2 Levels Correlate With Protection From Viremia

(2018) Ilona Baraniak et al.   JOURNAL OF INFECTIOUS DISEASES

Exploiting 2A peptides to elicit potent neutralizing antibodies by a multi-subunit herpesvirus glycoprotein complex

(2018) Felix Wussow et al.   JOURNAL OF VIROLOGICAL METHODS

Advancing Our Understanding of Protective Maternal Immunity as a Guide for Development of Vaccines To Reduce Congenital Cytomegalovirus Infections

(2018) Sallie R. Permar et al.   JOURNAL OF VIROLOGY

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions

(2018) Cody S. Nelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity

(2018) Shinu John et al.   VACCINE

Effects of pre-existing orthopoxvirus-specific immunity on the performance of Modified Vaccinia virus Ankara-based influenza vaccines

(2018) Arwen F. Altenburg et al.   Scientific Reports

Congenital Human Cytomegalovirus Infection and the Enigma of Maternal Immunity

(2017) William J. Britt   JOURNAL OF VIROLOGY

Identification of a Continuous Neutralizing Epitope within UL128 of Human Cytomegalovirus

(2017) Flavia Chiuppesi et al.   JOURNAL OF VIROLOGY

Maternal immune correlates of protection against placental transmission of cytomegalovirus

(2017) Hannah L. Itell et al.   PLACENTA

Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

(2017) Flavia Chiuppesi et al.   PLoS One

Polyfunctional T-Cell Signatures to Predict Protection from Cytomegalovirus after Lung Transplantation

(2016) Laurie D. Snyder et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

(2016) Corinna La Rosa et al.   BLOOD

Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector

(2016) Mark R. Schleiss et al.   Clinical and Vaccine Immunology

Cytomegalovirus Vaccines: Current Status and Future Prospects

(2016) K. M. Anderholm et al.   DRUGS

A replication-defective human cytomegalovirus vaccine for prevention of congenital infection

(2016) D. Wang et al.   Science Translational Medicine

Safety and efficacy of a cytomegalovirus glycoprotein B (gB) vaccine in adolescent girls: A randomized clinical trial

(2016) David I. Bernstein et al.   VACCINE

Expression of the human cytomegalovirus pentamer complex for vaccine use in a CHO system

(2015) Irmgard Hofmann et al.   BIOTECHNOLOGY AND BIOENGINEERING

Reduced Frequencies of Polyfunctional CMV-Specific T Cell Responses in Infants with Congenital CMV Infection

(2015) Laura Gibson et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection

(2015) Flavia Chiuppesi et al.   JOURNAL OF VIROLOGY

The history of vaccination against cytomegalovirus

(2015) Stanley Plotkin   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Maternal CD4+T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

(2015) Kristy M. Bialas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional patterns of cytomegalovirus (CMV) pp65 and immediate early-1-specific CD8+T cells that are associated with protection from and control of CMV DNAemia after allogeneic stem cell transplantation

(2015) E. Giménez et al.   Transplant Infectious Disease

Crystal Structure of the Human Cytomegalovirus Glycoprotein B

(2015) Heidi G. Burke et al.   PLoS Pathogens

A Randomized Trial of Hyperimmune Globulin to Prevent Congenital Cytomegalovirus

(2014) Maria Grazia Revello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies

(2014) Anna Kabanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human cytomegalovirus gH/gL/UL128/UL130/UL131A complex elicits potently neutralizing antibodies in mice

(2014) Yingxia Wen et al.   VACCINE

A Neutralizing Anti-gH/gL Monoclonal Antibody Is Protective in the Guinea Pig Model of Congenital CMV Infection

(2014) Marcy R. Auerbach et al.   PLoS Pathogens

Human Cytomegalovirus Vaccine Based on the Envelope gH/gL Pentamer Complex

(2014) Felix Wussow et al.   PLoS Pathogens

The “Silent” Global Burden of Congenital Cytomegalovirus

(2013) Sheetal Manicklal et al.   CLINICAL MICROBIOLOGY REVIEWS

Fetal Human Cytomegalovirus Transmission Correlates with Delayed Maternal Antibodies to gH/gL/pUL128-130-131 Complex during Primary Infection

(2013) Daniele Lilleri et al.   PLoS One

Recombinant MVA vaccines: dispelling the myths

(2013) Matthew G. Cottingham et al.   VACCINE

Utilizing poxviral vectored vaccines for antibody induction—Progress and prospects

(2013) Simon J. Draper et al.   VACCINE

Clinical development of Modified Vaccinia virus Ankara vaccines

(2013) Sarah C. Gilbert   VACCINE

The immune response to human CMV

(2012) Corinna La Rosa et al.   Future Virology

Antibodies Against Neutralization Epitopes of Human Cytomegalovirus gH/gL/pUL128-130-131 Complex and Virus Spreading May Correlate with Virus Control In Vivo

(2012) Daniele Lilleri et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A Vaccine Based on the Rhesus Cytomegalovirus UL128 Complex Induces Broadly Neutralizing Antibodies in Rhesus Macaques

(2012) Felix Wussow et al.   JOURNAL OF VIROLOGY

Antibodies against the gH/gL/UL128/UL130/UL131 Complex Comprise the Majority of the Anti-Cytomegalovirus (Anti-CMV) Neutralizing Antibody Response in CMV Hyperimmune Globulin

(2012) A. E. Fouts et al.   JOURNAL OF VIROLOGY

A Myeloid Progenitor Cell Line Capable of Supporting Human Cytomegalovirus Latency and Reactivation, Resulting in Infectious Progeny

(2012) Christine M. O'Connor et al.   JOURNAL OF VIROLOGY

Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay

(2012) Bhavin S. Parekh et al.   mAbs

Restoration of viral epithelial tropism improves immunogenicity in rabbits and rhesus macaques for a whole virion vaccine of human cytomegalovirus

(2012) Tong-Ming Fu et al.   VACCINE

Vectored co-delivery of human cytomegalovirus gH and gL proteins elicits potent complement-independent neutralizing antibodies

(2012) Rebecca J. Loomis et al.   VACCINE

Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice

(2012) Devon J. Shedlock et al.   Human Vaccines & Immunotherapeutics

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

(2011) S. F. Lacey et al.   BLOOD

Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial

(2011) Paul D Griffiths et al.   LANCET

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Attribution of Congenital Cytomegalovirus Infection to Primary Versus Non-Primary Maternal Infection

(2010) C. Wang et al.   CLINICAL INFECTIOUS DISEASES

Rapid generation of markerless recombinant MVA vaccines by en passant recombineering of a self-excising bacterial artificial chromosome

(2010) Matthew G. Cottingham et al.   JOURNAL OF VIROLOGICAL METHODS

Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses

(2010) Edwin R. Manuel et al.   VIROLOGY

Elucidating and Minimizing the Loss by Recombinant Vaccinia Virus of Human Immunodeficiency Virus Gene Expression Resulting from Spontaneous Mutations and Positive Selection

(2009) L. S. Wyatt et al.   JOURNAL OF VIROLOGY

Isolation of Human Monoclonal Antibodies That Potently Neutralize Human Cytomegalovirus Infection by Targeting Different Epitopes on the gH/gL/UL128-131A Complex

(2009) A. Macagno et al.   JOURNAL OF VIROLOGY

Vaccine Prevention of Maternal Cytomegalovirus Infection

(2009) Robert F. Pass et al.   NEW ENGLAND JOURNAL OF MEDICINE

Red-Mediated Transposition and Final Release of the Mini-F Vector of a Cloned Infectious Herpesvirus Genome

(2009) Felix Wussow et al.   PLoS One

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines

(2009) Zhongde Wang et al.   VACCINE

A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models

(2008) A KRISHNAN et al.   IMMUNOLOGY LETTERS

Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

(2008) Matthew G. Cottingham et al.   PLoS One

Induction of Pluripotent Protective Immunity Following Immunisation with a Chimeric Vaccine against Human Cytomegalovirus

(2008) Jie Zhong et al.   PLoS One