A Vaccine Based on the Rhesus Cytomegalovirus UL128 Complex Induces Broadly Neutralizing Antibodies in Rhesus Macaques

Antibodies against the gH/gL/UL128/UL130/UL131 Complex Comprise the Majority of the Anti-Cytomegalovirus (Anti-CMV) Neutralizing Antibody Response in CMV Hyperimmune Globulin

(2012) A. E. Fouts et al.   JOURNAL OF VIROLOGY

A novel therapeutic cytomegalovirus DNA vaccine in allogeneic haemopoietic stem-cell transplantation: a randomised, double-blind, placebo-controlled, phase 2 trial

(2012) Mohamed A Kharfan-Dabaja et al.   LANCET INFECTIOUS DISEASES

Human cytomegalovirus entry into cells

(2012) Adam L Vanarsdall et al.   Current Opinion in Virology

Serum antibody response to the gH/gL/pUL128–131 five-protein complex of human cytomegalovirus (HCMV) in primary and reactivated HCMV infections

(2011) Emilia Genini et al.   JOURNAL OF CLINICAL VIROLOGY

Open Reading Frames Carried on UL/b' Are Implicated in Shedding and Horizontal Transmission of Rhesus Cytomegalovirus in Rhesus Monkeys

(2011) K. L. Oxford et al.   JOURNAL OF VIROLOGY

Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial

(2011) Paul D Griffiths et al.   LANCET

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

(2011) Frances M. Saccoccio et al.   VACCINE

Quantitative analysis of neutralizing antibody response to human cytomegalovirus in natural infection

(2011) Dai Wang et al.   VACCINE

Cytomegalovirus vaccines and methods of production (WO20009049138): the emerging recognition of the importance of virus neutralization at the epithelial/endothelial interface

(2010) Mark R Schleiss   EXPERT OPINION ON THERAPEUTIC PATENTS

Vaccine-Induced Control of Viral Shedding following Rhesus Cytomegalovirus Challenge in Rhesus Macaques

(2010) K. Abel et al.   JOURNAL OF VIROLOGY

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implications

(2010) M. Grazia Revello et al.   REVIEWS IN MEDICAL VIROLOGY

Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses

(2010) Edwin R. Manuel et al.   VIROLOGY

Birth Prevalence and Natural History of Congenital Cytomegalovirus Infection in a Highly Seroimmune Population

(2009) Marisa M. Mussi‐Pinhata et al.   CLINICAL INFECTIOUS DISEASES

Cytomegalovirus Reinfections in Healthy Seroimmune Women

(2009) Shannon A. Ross et al.   JOURNAL OF INFECTIOUS DISEASES

Human Cytomegalovirus TR Strain Glycoprotein O Acts as a Chaperone Promoting gH/gL Incorporation into Virions but Is Not Present in Virions

(2009) B. J. Ryckman et al.   JOURNAL OF VIROLOGY

Elucidating and Minimizing the Loss by Recombinant Vaccinia Virus of Human Immunodeficiency Virus Gene Expression Resulting from Spontaneous Mutations and Positive Selection

(2009) L. S. Wyatt et al.   JOURNAL OF VIROLOGY

Isolation of Human Monoclonal Antibodies That Potently Neutralize Human Cytomegalovirus Infection by Targeting Different Epitopes on the gH/gL/UL128-131A Complex

(2009) A. Macagno et al.   JOURNAL OF VIROLOGY

A Human Cytomegalovirus gO-Null Mutant Fails To Incorporate gH/gL into the Virion Envelope and Is Unable To Enter Fibroblasts and Epithelial and Endothelial Cells

(2009) P. T. Wille et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus Glycoprotein B Is Required for Virus Entry and Cell-to-Cell Spread but Not for Virion Attachment, Assembly, or Egress

(2009) M. K. Isaacson et al.   JOURNAL OF VIROLOGY

Vaccine Prevention of Maternal Cytomegalovirus Infection

(2009) Robert F. Pass et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers

(2009) David I. Bernstein et al.   VACCINE

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines

(2009) Zhongde Wang et al.   VACCINE

Human cytomegalovirus serum neutralizing antibodies block virus infection of endothelial/epithelial cells, but not fibroblasts, early during primary infection

(2008) G. Gerna et al.   JOURNAL OF GENERAL VIROLOGY

Human Cytomegalovirus Glycoproteins gB and gH/gL Mediate Epithelial Cell-Cell Fusion When Expressed either in cis or in trans

(2008) A. L. Vanarsdall et al.   JOURNAL OF VIROLOGY

Evaluation of recombinant modified vaccinia Ankara virus-based rhesus cytomegalovirus vaccines in rhesus macaques

(2008) Yujuan Yue et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

(2008) Matthew G. Cottingham et al.   PLoS One

Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types

(2008) A. E. Lilja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCMV gH/gL/UL128-131 interferes with virus entry into epithelial cells: Evidence for cell type-specific receptors

(2008) B. J. Ryckman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A heterologous DNA prime/protein boost immunization strategy for rhesus cytomegalovirus

(2008) Kristina Abel et al.   VACCINE

Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection

(2008) Xiaohong Cui et al.   VACCINE

Protein coding content of the ULb′ region of wild-type rhesus cytomegalovirus

(2008) Kristie L. Oxford et al.   VIROLOGY